Primary Care

Preventive Care

Latest AI and machine learning research in preventive care for healthcare professionals.

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Deep learning model applied to real-time delineation of colorectal polyps.

BACKGROUND: Deep learning models have shown considerable potential to improve diagnostic accuracy across medical fields. Although YOLACT has demonstrated real-time detection and segmentation in non-medical datasets, its application in medical settings remains underexplored. This study evaluated the performance of a YOLACT-derived Real-time Polyp Delineation Model (RTPoDeMo) for real-time use on pr...

Jun 4 2025 40468304

Ground-State Descriptor Enables Machine Learning-Assisted Virtual Screening of AIE-Active Mechanofluorochromic Molecules with High Contrast.

Aggregation-induced emission mechanofluorochromic (AIE-MFC) molecules with high-contrast are in high demand for pressure-sensing devices and optoelectronic devices. However, developing AIE-MFC molecules with high-contrast beyond 100 nm still highly relies on scientific intuition through experimental and traditional trial-and-error methods. Herein, we establish a new electronic descriptor E (the or...

Jun 1 2025 40450681
Development and Validation of a Lifestyle-Based 10-Year Risk Prediction Model of Colorectal Cancer for Early Stratification: Evidence from a Longitudinal Screening Cohort in China.

Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with growing evidence linking risk to lifestyle and ...

May 31 2025 40507167
One-Drop Serum Screening Test to Monitor Tissue Iron Accumulation.

Although iron is an essential element for vital body functions, iron overload (IO) is accompanied by significant cellular damage due to its accumulati...

May 30 2025 40446114
Screening/Diagnosing Sarcopenia with Machine Learning-Powered Risk Assessment: The SARCO X Study.

OBJECTIVES: Sarcopenia imposes significant morbidity and economic burden on health care systems, underscoring the critical need for early/effective sc...

May 30 2025 40383138
RhDnostics: A Machine Learning-Based Predictive Algorithm Model for RhD-Negative and DEL Blood Group Screening.

BACKGROUND: The D-elution (DEL) phenotype is serologically mislabeled as Rh-negative because of the very low amount of D antigen on red blood cells. T...

May 30 2025 40444812
Advancing Musculoskeletal Care Using AI and Digital Health Applications: A Review of Commercial Solutions.

Artificial intelligence (AI) and digital health (DH) solutions are reshaping musculoskeletal (MSK) care across diagnostics, treatment planning, workfl...

May 30 2025 40458230
DPP-IV inhibitory peptides from highland barley via machine learning and multi-scale validation.

Highland barley has shown potential in regulating blood glucose and may serve as a natural source of dipeptidyl peptidase-IV (DPP-IV) inhibitors. In t...

May 30 2025 40460479
DrugPipe: Generative artificial intelligence-assisted virtual screening pipeline for generalizable and efficient drug repurposing.

Drug repurposing presents a promising strategy to accelerate drug discovery by identifying new therapeutic uses for existing compounds, particularly f...

May 30 2025 40486179
Artificial intelligence in endoscopy and colonoscopy: a comprehensive bibliometric analysis of global research trends.

BACKGROUND: Artificial intelligence (AI) has revolutionized the field of gastroenterology, particularly in endoscopic and colonoscopic procedures. The...

May 30 2025 40520787
In Silico Screening of Small Molecule Inhibitors for Amyloid-β Aggregation.

The self-aggregation of amyloid-β (Aβ) into fibrils is a hallmark of Alzheimer's disease (AD). Inhibition of Aβ aggregation with small molecule compou...

May 29 2025 40442621
Machine Learning for Predicting Colorectal Cancer and Advanced Colorectal Polyps: A Systematic Review and Meta-Analysis.

INTRODUCTION: Machine learning (ML) has become increasingly pivotal in health care, particularly in colorectal cancer (CRC) detection and diagnosis wi...

May 29 2025 40434809
CervicalMethDx: a precision DNA methylation test to identify risk of high-grade intraepithelial lesions in cervical cancer screening algorithms.

Cervical cancer is one of the most common cancers in women. Despite progress in prevention and success in early detection through cytologic screening ...

May 29 2025 40439417
The Augmented Colonoscopy with Computer-Aided polyp Characterization (AC-CADx) study - prospective study comparing the diagnostic reliability of optical diagnosis of trainees with experts without AI.

INTRODUCTION: Optical diagnosis is an essential part of a high-quality colonoscopy, but highly experience-dependent. Artificial intelligence in the fo...

May 28 2025 40434246
Multi-Scale Vision Transformer with Optimized Feature Fusion for Mammographic Breast Cancer Classification.

: Breast cancer remains one of the leading causes of mortality among women worldwide, highlighting the critical need for accurate and efficient diagno...

May 28 2025 40506933
Future Perspectives of Liver Research in the Asia-Pacific Region: Focus on Hepatitis B and C.

The Asia-Pacific region faces serious liver health challenges, primarily because of the comparatively high prevalence of hepatitis B virus (HBV) and h...

May 27 2025 40423265
Clinical significance of computer-aided quality assessment systems in colonoscopy: a comprehensive review.

Colonoscopy is the primary tool for colorectal cancer screening. High-quality colonoscopy is crucial for the detection of precancerous adenomas; howev...

May 27 2025 40438910
Emerging blood biomarkers in Alzheimer's disease: a proteomic perspective.

Early detection of Alzheimer's disease (AD) remains a formidable clinical challenge, but emerging blood-based assays show promise for identifying at-r...

May 27 2025 40441344
Deep learning architectures for influenza dynamics and treatment optimization: a comprehensive review.

As a major worldwide health concern, influenza still requires precise modeling of flu dynamics and efficient treatment approaches. Deep learning archi...

May 27 2025 40495931
Screening and identification of novel protein markers of early-stage lung cancer and construction and application of screening models.

OBJECTIVE: Molecular biomarkers have the potential to improve the current state of early screening of lung cancer. This investigation aimed to identif...

May 27 2025 40496615
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