Latest AI and machine learning research in primary care for healthcare professionals.
Alzheimer's disease (AD) remains a major global health challenge, with current therapies offering only symptomatic relief. A significant constraint in the development of effective treatments is the blood-brain barrier (BBB), as it greatly limits the access of therapeutic drugs targeting amyloid-β (Aβ) aggregation, tau hyperphosphorylation and neuroinflammation. Nanobodies, single-domain antibody f...
OBJECTIVE: The lung is commonly involved in advanced Kaposi sarcoma (KS) but diagnosis of pulmonary KS in low-resource settings is difficult. Clinical assessments were evaluated to improve screening for pulmonary KS in a low-resource setting. METHODS: A longitudinal cohort of Africans with HIV-associated KS in the Parirenyatwa Hospital KS clinic, Harare, Zimbabwe, was followed from 2016 to 2018. A...
Chronic Kidney Disease (CKD) refers to a persistent and progressive impairment of kidney function occurring over a prolonged duration. Impaired kidney...
INTRODUCTION: Obstetric ultrasound is fundamental in prenatal care for gestational age (GA) estimation, fetal monitoring, and complication screening. ...
BACKGROUND: Benign adrenal tumours, found in 1-7% of adults, can be non-functioning (NFAT) or show mild autonomous cortisol secretion (MACS), i.e., bi...
BACKGROUND: Cardiometabolic index (CMI) is a novel marker reflecting metabolic and cardiovascular health, but its role in spondyloarthritis (SpA) rema...
IMPORTANCE: Bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH) are leading causes of morbidity and mortality in premature infants. OBJEC...
Type 2 diabetic nephropathy (T2DN) is a major complication of type 2 diabetes and a leading cause of chronic kidney disease. This study aimed to explo...
PURPOSE: This cross-sectional study explored the association between sleep deprivation and epiretinal membrane (ERM) using machine learning applied to...
OBJECTIVES: This study aimed to investigate the impacts of chronic diseases such as hypertension, dyslipidaemia and diabetes on personal and household...
We present a cost-effective approach to evaluating road surface quality and roughness based on low-cost smartphones by leveraging accelerometer and gy...
Coagulation dysfunction, a common hematologic disorder with unclear pathogenesis, is influenced by environmental factors. Sodium dehydroacetate (SDA),...
BACKGROUND: The impact of discordance between remnant cholesterol (RC) and low-density lipoprotein cholesterol (LDL-c) on diabetes, diabetic kidney di...
Artificial intelligence (AI) holds promise for enhancing glaucoma screening and management, yet its adoption depends on clinician perceptions, particu...
Due to insufficient insulin secretion, patients with type 1 diabetes mellitus (T1DM) are prone to blood glucose fluctuations ranging from hypoglycemia...
INTRODUCTION: Stroke remains a leading cause of global morbidity and mortality, ranking second in deaths and third in disability-adjusted life years (...
INTRODUCTION: Stroke ranks as the second-leading cause of death and third in combined death and disability globally. In Ghana, there is a significant ...
BACKGROUND. Insights into the nature of false-positive findings flagged by contemporary mammography artificial intelligence (AI) systems could inform ...
BACKGROUND AND STUDY AIMS: Polypectomy-related costs could potentially be reduced through optical diagnosis strategies, such as 'diagnose-and-leave' a...
BACKGROUND: Oral cancers account for considerable morbidity and mortality worldwide, and their incidence has increased in the past several years, desp...