Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Challenges in the diagnosis and management of hypertrophic cardiomyopathy and the promise of artificial intelligence.

Hypertrophic cardiomyopathy (HCM), the most prevalent inherited cardiomyopathy, is characterized by left ventricular hypertrophy that typically manifests with asymmetric wall thickening and is not caused by a pressure overload state or systemic disease. Despite its considerable prevalence-estimated to affect up to 1 in 200 individuals based on imaging data-it often goes undiagnosed or misdiagnosed...

Dec 18 2025 41421434

Supragingival Biomarker flora of Children With and Without Cariogenic Disease and Black Stains, Aged 3 to 6 Years.

BACKGROUND: The oral microbiome plays a pivotal role in the occurrence and progression of dental caries and black stain (BS) pigment. OBJECTIVES: The aim of this study was to explore the keystone microbiota and potential biomarkers of caries and BS pigment in 3 to 6-year-old children. METHODS: A total of 122 children were included, namely, healthy controls (HC, n = 32), those with severe early chi...

Dec 18 2025 41418677
Artificial Intelligence-Based Delirium Prediction Model for Post-Cardiac Surgery Patients: A Scoping Review.

BACKGROUND: Delirium is a common complication following cardiac surgery and significantly affects patient prognosis and quality of life. Recently, the...

Dec 17 2025 41410092
Pathway to precision: machine learning and bioinformatics in diabetes gene expression studies.

BACKGROUND: Diabetes mellitus is a metabolic disorder; understanding the pathogenic mechanisms underlying diabetes is crucial. Analyzing biomarkers, s...

Dec 17 2025 41424950
Progress in constitutive modeling of arterial wall tissue mechanics: from theoretical frameworks to clinical application.

Cardiovascular disease (CVD) is a leading cause of mortality worldwide, and the mechanical behavior of arterial wall tissue (AWT) is central to its in...

Dec 17 2025 41418938
Acceptability of Using Artificial Intelligence in the National Health Service Breast Screening Program: A Randomized Online Survey of Screening-Eligible Women in England.

OBJECTIVE: To compare acceptability of 2 artificial intelligence (AI) use cases in the English National Health Servic Breast Screening Program. PATIEN...

Dec 17 2025 41607508
Clinical Decision Support Systems for cancer symptom management: A scoping review.

BACKGROUND: Effective cancer symptom management significantly impacts patient outcomes and quality of life. While Clinical Decision Support Systems sh...

Dec 16 2025 41442839
Sociodemographic Predictors of Child-Parent Agreement on Oral Health.

BACKGROUND: Oral health is vital for children's overall well-being. Parents play a critical role in shaping children's oral health through preventive ...

Dec 15 2025 41399055
Literature-informed ensemble machine learning for three-year diabetic kidney disease risk prediction in type 2 diabetes: Development, validation, and deployment of the PSMMC NephraRisk model.

INTRODUCTION: Diabetic kidney disease (DKD) and diabetic nephropathy (DN) affect around 40% of diabetic patients but lack accurate risk prediction too...

Dec 15 2025 41395651
Diagnostic modalities in pediatric obstructive sleep apnea: A review article.

BACKGROUND: Pediatric obstructive sleep apnea (OSA) affects ∼3 % of children and causes adverse neurocognitive, behavioral, and cardiovascular outcome...

Dec 15 2025 41418344
Precision dermatology 2050: AI-driven personalized monitoring and individualized treatment.

By 2050, advances in artificial intelligence (AI), Internet of Medical Things (IoMT) and teledermatology are predicted to fundamentally transform the ...

Dec 14 2025 41392515
Multi-center-validated machine learning model for cervical cancer based on human papillomavirus genotyping results.

OBJECTIVE: Cervical cancer remains a leading cause of gynecologic cancer-related mortality worldwide, with human papillomavirus (HPV) testing being a ...

Dec 13 2025 42102630
A Learning Accelerator Framework: Scalable Clinical Artificial Intelligence Development and Delivery.

OBJECTIVES: To introduce a vertically integrated model between a health care service provider and technology developer as a learning accelerator to ad...

Dec 13 2025 41391717
Advances in the application of artificial intelligence in mass spectrometry-based analysis of traditional Chinese medicine: compound identification and metabolic pathway elucidation.

Traditional Chinese medicine (TCM), characterized by its multi-component, multi-target, and multi-pathway nature, presents considerable challenges in ...

Dec 13 2025 41389153
Advances in endometrial cancer screening: a comprehensive review of current methods and emerging technologies.

Endometrial cancer represents a major global health concern, with rising incidence particularly in developed countries despite declining mortality rat...

Dec 12 2025 41385140
Predictive Modeling of Cancer Information Overload and Screening Attitudes: A Cross-Sectional Study.

OBJECTIVE: To explore the association between cancer information overload and attitudes toward cancer screening among internal medicine patients. AIMS...

Dec 12 2025 41390249
Evaluating the cost-effectiveness of artificial intelligence-enhanced osteoporosis screening in men and women using routine chest radiographs in South Korea.

South Korea, now a "super-aged" society, faces a rising burden of fragility fractures, yet underdiagnosis remains a major barrier, with limited DXA ac...

Dec 12 2025 41522667
Clinical Phenotypes in Hypertension: A Data-Driven Approach to Risk Stratification.

BACKGROUND: Hypertension is a major contributor to cardiovascular morbidity and mortality. Its heterogeneity complicates risk stratification. Unsuperv...

Dec 11 2025 41376588
AI-powered literature mining reveals the therapeutic significance of GLP-1 receptor: Simulation of natural agonist candidates based on molecular dynamics.

Glucagon-like peptide-1 (GLP-1), a pivotal incretin hormone modulating glycemic homeostasis, has emerged as a clinically validated target for the trea...

Dec 11 2025 41389576
Enzyme-based biosensors: emerging tools for advanced biomedical applications.

Proteins and enzymes are fundamental elements for the correct regulation of cell metabolism and their dysregulation or malfunction can lead to the ons...

Dec 11 2025 41389693
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