Primary Care

Decoding Parkinson's progression: A multi-modal SuStaIn ensemble approach validated on real-world PPMI data.

BACKGROUND: Parkinson's disease (PD) exhibits substantial heterogeneity in clinical presentation and...

AI-Driven Discovery of an Allosteric Thrombin-Targeting Anticoagulant Peptide from Traditional Chinese Medicine Dilong (Pheretima aspergillum).

ETHNOPHARMACOLOGICAL RELEVANCE: Dilong, the dried body of Pheretima aspergillum, is a classic tradit...

EJHF expert consensus statement on the diagnosis and management of hypertrophic cardiomyopathy.

Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiac disease and a leading cause ...

Combining Machine Learning Models and Screening to Enhance Suicide Risk Identification for American Indian Patients: Retrospective Cohort Study.

BACKGROUND: American Indian and Alaska Native communities experience disproportionately high suicide...

AI-powered evaluation of dementia severity based on clinical data and visual scoring systems (MTA, ERICA, GCA) from MRI.

Dementia, particularly Alzheimer's disease (AD), is a growing concern in aging populations, with mil...

An exploratory study of multi-channel CNN for early detection of lung cancer from longitudinal healthcare records.

Lung cancer remains the leading cause of cancer-related mortality worldwide, with poor survival rate...

Machine learning prediction for menopause women with low bone mass: a multicenter and retrospective study.

Early diagnosis of postmenopausal osteoporosis provides an opportunity to detect and prevent fractur...

[Artificial intelligence in pediatric ophthalmology: applications and perspectives].

Pediatric visual health is not only inextricably linked to an individual's lifelong cognitive develo...

Transforming hypoglycemia prediction in adult type 1 diabetes: a systematic review and meta-analysis for precision care.

Type 1 diabetes mellitus (T1DM) patients require lifelong insulin therapy; however, iatrogenic hypog...

Machine learning and regional homogeneity reveal early and subtle brain changes in type 1 diabetes.

BACKGROUND AND PURPOSE: Type 1 diabetes mellitus (T1DM) usually begins early in life, and its develo...

An artificial intelligence classifier as a screening tool to rule out otitis media in children.

OBJECTIVE: Acute otitis media is the most common bacterial infection among children and a significan...

Comment on "A machine learning approach to predicting severe diabetes distress in adults with type 1 diabetes mellitus".

Artificial intelligence-driven rational design and optimization of a potent terpenoid-derived PCSK9 inhibitor.

Hypercholesterolemia is a pivotal risk factor for cardiovascular diseases, and its effective managem...

Clinician engagement shapes the impact of AI-based ECG screening for chronic liver disease in primary care.

Artificial intelligence (AI)-based screening tools show promise for early identification of chronic ...

When to stop reviewing: validation of stop criteria in ASReview.

BACKGROUND: Systematic reviews are essential for evidence-based research, but they often require a g...

Molecular basis of precision nutrition: Food components, microbiome-derived metabolites, and multi-omics modeling.

Metabolic disorders, including obesity, type 2 diabetes, metabolic syndrome, and fatty liver disease...

Beyond the Mean: A Machine Learning-Based Trend Analysis of CGM Metrics for Improved HbA1C Estimation in Type 2 Diabetes.

BACKGROUND: Hemoglobin A1C (HbA1C) is the gold standard for assessing long-term glycemic control in ...

From Lumen to Myocardium With Artificial Intelligence: A Clinician's Guide to Comprehensive Cardiac CT.

Coronary artery disease assessment has long focused on stenosis severity, yet luminal narrowing alon...

Communication-Based Teaching on Childhood Obesity and the Planetary Health Diet in Medical Education: Proof-of-Concept Study Comparing 4 Information Sources.

BACKGROUND: Childhood obesity constitutes a complex medical and psychosocial challenge that requires...

Machine Learning-Based Multidimensional Oximetry for Obstructive Sleep Apnea Screening: Development and External Validation.

BACKGROUND: Obstructive sleep apnea (OSA) affects nearly one billion people globally and poses a sub...

Bridging survival analysis and machine learning to improve healthy life expectancy estimation using PHR records.

Healthy Life Expectancy (HLE) considers the years an individual has lived free of disease. Minimisin...