Primary Care

Promethazine for nausea and vomiting prevention after gynaecological laparoscopic surgery: A randomized controlled trial.

Postoperative nausea and vomiting (PONV) represent significant concerns for patients undergoing surgical procedures, as these symptoms greatly impact their postoperative experience. Among female patients undergoing laparoscopic surgery, the incidence of PONV is estimated to be approximately 45%. Moreover, for those individuals who have not undergone preventive treatment, the risk of experiencing P...

Isolation and characterization of a bioactive compound from Sphingomonas sanguinis DM with cytotoxic and molecular docking analysis.

Datura metel, a common plant in the Solanaceae family, is known for its valuable medicinal properties. The metabolites created by its rhizosphere bacterium, Sphingomonas sanguinis DM, have garnered interest for their potential biological effects. This study will discuss the steps involved in fermenting and processing a bacterial strain to extract potent secondary metabolites. The ethyl acetate ext...

Simultaneous initiation of dolutegravir-based antiretroviral therapy and once-weekly rifapentine and isoniazid for tuberculosis prevention in antiretroviral-naive people with HIV: an open-label, non-randomised, phase 1/2 trial.

BACKGROUND: Tuberculosis preventive treatment with 3 months of once-weekly isoniazid (900 mg) and rifapentine (900 mg; 3HP) is a recommended option fo...

Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century.

Since the turn of the millennium, computational modelling of biological systems has evolved remarkably and sees matured use spanning basic and clinica...

From Genome to Phenome: Opportunities and Challenges of Molecular Imaging.

The study of the human phenome is essential for understanding the complexities of wellness and disease and their transitions, with molecular imaging b...

Association of Physical Activity from Wearable Devices and Chronic Disease Risk: Insights from the All of Us Research Program.

Physical activity is a modifiable factor influencing chronic disease risk. Previous studies often relied on self-reported activity measures or short-t...

Impact of the recent advances in coronary artery disease imaging on pilot medical certification and aviation safety: current state and future perspective.

Coronary artery disease (CAD) is highly prevalent among pilots due to the nature of their lifestyle, and occupational stresses. CAD is one the most co...

Optimizing Strategy for Lung Cancer Screening: From Risk Prediction to Clinical Decision Support.

PURPOSE: Low-dose computed tomography (LDCT) screening is effective in reducing lung cancer mortality by detecting the disease at earlier, more treata...

Artificial intelligence versus manual screening for the detection of diabetic retinopathy: a comparative systematic review and meta-analysis.

BACKGROUND: Diabetic retinopathy is one of the leading causes of blindness globally, among individuals with diabetes mellitus. Early detection through...

Invited Article: Al guided Dual Antiplatelet Therapy and Anticoagulation.

Artificial intelligence (AI) has emerged as a transformative tool in healthcare through data analysis, pattern recognition and predictive modeling cap...

Prediction of perimetric progression in ocular hypertension and open angle glaucoma based on corneal biomechanics.

PurposeTo identify parameters that are significant risk predictors of visual field (VF) progression in patients with ocular hypertension (OHT) or earl...

A Lesion-Fusion Neural Network for Multi-View Diabetic Retinopathy Grading.

As the most common complication of diabetes, diabetic retinopathy (DR) is one of the main causes of irreversible blindness. Automatic DR grading plays...

WavFace: A Multimodal Transformer-Based Model for Depression Screening.

Depression, a prevalent mental health disorder with severe health and economic consequences, can be costly and difficult to detect. To alleviate this ...

AI-driven personalized nutrition: RAG-based digital health solution for obesity and type 2 diabetes.

Effective management of obesity and type 2 diabetes is a major global public health challenge that requires evidence-based, scalable personalized nutr...

The Role of Computed Tomography and Artificial Intelligence in Evaluating the Comorbidities of Chronic Obstructive Pulmonary Disease: A One-Stop CT Scanning for Lung Cancer Screening.

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Comorbidities in patients with COPD significantly ...

Latent space autoencoder generative adversarial model for retinal image synthesis and vessel segmentation.

Diabetes is a widespread condition that can lead to serious vision problems over time. Timely identification and treatment of diabetic retinopathy (DR...

Game Design, Effectiveness, and Implementation of Serious Games Promoting Aspects of Mental Health Literacy Among Children and Adolescents: Systematic Review.

BACKGROUND: The effects of traditional health-promoting and preventive interventions in mental health and mental health literacy are often attenuated ...

The analysis of marketing performance in E-commerce live broadcast platform based on big data and deep learning.

This study aims to conduct a comprehensive and in-depth analysis of the marketing performance of e-commerce live broadcast platforms based on big data...

Cognitive impairment screening strategy to reduce the burden of Alzheimer's disease in Shanghai: A system dynamics approach.

BACKGROUND: Population aging increases the economic burden of Alzheimer's disease (AD). Early screening for mild cognitive impairment (MCI) has the po...

Multitask learning multimodal network for chronic disease prediction.

Chronic diseases are a critical focus in the management of elderly health. Early disease prediction plays a vital role in achieving disease prevention...