Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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AI-DRIVEN DIAGNOSIS OF NON-ALCOHOLIC FATTY LIVER DISEASE AND ASSOCIATED COMORBIDITIES

Non-alcoholic fatty liver disease (NAFLD) is a globally prevalent hepatic condition caused by the bu...

Deep Agentic Variant Prioritisation for Expert Level Genetic Diagnosis Fast at Scale

Abstract. Genetic diagnosis remains a formidable challenge characterized by a diagnostic odyssey tha...

RosetteArray Platform for Quantitative High-Throughput Screening of Human Neurodevelopmental Risk

Neural organoids have revolutionized how human neurodevelopmental disorders (NDDs) are studied. Yet,...

Collaborative large language models (LLMs) are all you need for screening in systematic reviews

Background: The ability of large language models (LLMs) to work collaboratively and screen studies i...

Multi-Model Clinical Validation of an AI-Powered Biomarker Analysis Framework: A Cross-Vendor Benchmark on 4,018 NHANES Patients

Background: Large language models (LLMs) show promise for clinical decision support, yet most valida...

BindCLIP: A Unified Contrastive-Generative Representation Learning Framework for Virtual Screening

Virtual screening aims to efficiently identify active ligands from massive chemical libraries for a ...

CausalCellInfer: Resolving cell-type-specific disease mechanisms from biobank-scale GWAS

Integrating the cellular resolution of single-cell RNA sequencing (scRNA-seq) with the phenotypic de...

A radiation-free screening system for adolescent idiopathic scoliosis using deep learning on 3D back surface point clouds

Widespread screening for Adolescent Idiopathic Scoliosis (AIS) is critical for timely intervention b...

Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights

Body mass index (BMI), type 2 diabetes (T2D) and associated cardiometabolic features modify Alzheime...

Cellular Aging Signatures in the Plasma Proteome Record Human Health and Disease

Aging is asynchronous across cells and organs, but whether plasma proteins can capture cell type-spe...

AI-Driven Clinical Decision Support System for Enhanced Diabetes Diagnosis and Management

Identifying type 2 diabetes mellitus can be challenging, particularly for primary care physicians. C...

LLM-based reconstruction of longitudinal clinical trajectories in chronic liver disease.

Background: Liver cancer primarily develops in patients with chronic liver disease (CLD), yet most c...

Uncertainty-Aware Ordinal Deep Learning for cross-Dataset Diabetic Retinopathy Grading

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to i...

Patient foundation model for risk stratification in low-risk overweight patients

Accurate risk stratification in patients with overweight or obesity is critical for guiding preventi...

Epistemic Throughput: Fundamental Limits of Attention-Constrained Inference

Recent generative and tool-using AI systems can surface a large volume of candidates at low marginal...

Machine Learning Phenotyping of Autonomic Stress from Daily Temperature and Ecological Assessments

Background: Artificial intelligence applications for preventive stress monitoring remain limited by ...

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