Primary Care

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Scaling genetic discovery for organ volumes using machine learning-assisted imputation and bias-corrected GWAS

MRI-derived organ and tissue volumes are powerful endophenotypes for studying complex disease, but t...

Comparing different types of machine learning models in diagnosing diabetes mellitus utilizing electrocardiography and clinical data

Diabetes Mellitus (DM) represents one of the most significant global public health challenges of the...

LLM-based Multi-Agent Collaboration for Abstract Screening towards Automated Systematic Reviews

Systematic reviews (SRs) are essential for evidence-based practice but remain labor-intensive, espec...

A Novel Method to Disentangle Tightly Linked Risk and Resilience Genes for Brain Disorders: Application to Alzheimer’s Disease

Genetic risk factors for neuropsychiatric disorders are well documented. However, some individuals w...

Machine learning-based prediction of future dementia using routine clinical MRI brain scans and healthcare data

Early identification of dementia risk is essential for preventive care and timely enrolment into dis...

Assessment of fatal cardiovascular disease risk using data-driven diabetes subgroups and SCORE2-Diabetes in 24,943 adults in Mexico City

Cardiovascular disease (CVD) is a leading cause of diabetes-related mortality in Mexico. Although di...

Incorporating Dietary Information to Enhance Polygenic Prediction Models with Applications to Body Mass Index and Type 2 Diabetes

Polygenic predictors can enhance screening for biomedical conditions, such as metabolism-related tra...

Precision Immunosuppression and Long-Term Kidney Transplant Outcomes: A Dual Survival Modeling Framework

Optimizing immunosuppressive therapy remains central to improving long-term outcomes after kidney tr...

Genetic and Etiological Insights from Automated Lumen Diameter Measurements in Carotid Ultrasounds of the UK Biobank

Carotid ultrasound is routinely used in clinical practice for non-invasive vascular anatomical and f...

Machine Learning Analysis of Post-Acute COVID Symptoms Identifies Distinct Clusters, Severity Groups, and Trajectories

Questionnaires that capture patient-reported symptomatology provide low-cost but potentially high-va...

A Large-Scale Serum Metabolite Panel for Baseline Detection of Alzheimer’s Disease

Blood-based metabolomic signatures offer promising, non-invasive avenues for Alzheimer’s disease (AD...

A Tabular Residual Neural Network for Diabetes Classification and Prediction

Diabetes Mellitus (DM) is a metabolic disorder characterized by hyperglycemia, with type 1 character...

An Artificial Intelligence Model for Detection of Heart Failure with Preserved Ejection Fraction: A Report from HeartShare Study

Heart failure with preserved ejection fraction (HFpEF) accounts for over half of all heart failure c...

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