Primary Care

Dual-Mode Detection of Trypsin and Screening of Trypsin Inhibitors on the Basis of a Colorimetric/Fluorescence Sensing Probe.

Trypsin is a specific and reliable diagnostic biomarker of pancreatic function and pathological chan...

Intravascular Lithotripsy Versus Rotational Atherectomy for Calcified Coronary Lesions: A Systematic Review and an Updated Meta-Analysis of Clinical Outcomes.

BACKGROUND: Severe coronary artery calcification (CAC) remains a significant challenge in interventi...

Multi-technique computational assessment of fluoride uptake in enamel using PIGE, NEXAFS, and Raman spectroscopy.

The uptake of fluoride in the enamel matrix is an effective strategy to prevent demineralization and...

Serum sclerostin as a marker of microvascular and macrovascular complications among children and adolescents with type 1 diabetes mellitus.

BACKGROUND: Uncontrolled diabetes mellitus (DM) accelerates atherosclerosis and vascular diseases, l...

An All-in-one Nanohole Array for Size-Exclusive Trapping and High-Throughput Digital Counting of Single Extracellular Vesicles for Non-invasive Cancer Screening.

The analysis of single small extracellular vesicles (sEVs) could distinguish the heterogeneity of sE...

Semi-quantitative analysis of Right Ventricular Myocardial First-pass Perfusion Using Cardiac Magnetic Resonance Imaging in Systemic Sclerosis and Pulmonary Arterial Hypertension.

BACKGROUND: Right ventricular (RV) myocardial perfusion has been touted as a primary mechanism to un...

Diabetic retinopathy-recommendations for screening and treatment.

Diabetic retinopathy (DR), the prevalence of which continues to rise, is one of the most common caus...

Impact of type 2 diabetes mellitus on apical periodontitis size, endotoxin levels and bacterial load in root canals with necrotic pulp.

INTRODUCTION: This clinical study was conducted to describe the endodontic microbiological profile o...

Artificial intelligence improves breast cancer detection in mammography screening.

Detection of ESBL-producing complex with VITEK 2 system and screening cutoffs for implementing confirmatory tests.

complex (C) are important nosocomial pathogens that can be reservoirs of transmissible extended-spe...

Simultaneous initiation of dolutegravir-based antiretroviral therapy and once-weekly rifapentine and isoniazid for tuberculosis prevention in antiretroviral-naive people with HIV: an open-label, non-randomised, phase 1/2 trial.

BACKGROUND: Tuberculosis preventive treatment with 3 months of once-weekly isoniazid (900 mg) and ri...

Isolation and characterization of a bioactive compound from Sphingomonas sanguinis DM with cytotoxic and molecular docking analysis.

Datura metel, a common plant in the Solanaceae family, is known for its valuable medicinal propertie...

Bioactivity and chemical screening of endophytic fungi associated with seaweeds Gracilaria sp. and Sargassum sp. of the Bay of Bengal, Bangladesh.

This study explored the great potential of endophytic fungi associated with red seaweed Gracilaria s...

Promethazine for nausea and vomiting prevention after gynaecological laparoscopic surgery: A randomized controlled trial.

Postoperative nausea and vomiting (PONV) represent significant concerns for patients undergoing surg...

From Genome to Phenome: Opportunities and Challenges of Molecular Imaging.

The study of the human phenome is essential for understanding the complexities of wellness and disea...

Periodontal disease in adolescents with type 1 diabetes mellitus: A cross link between continuous glucose monitoring-derived metrics, caspase-3 levels, diabetic nephropathy and subclinical atherosclerosis.

BACKGROUND: Periodontitis can lead to the development of atherosclerotic heart disease.

Non-proliferative diabetic retinopathy detection using Rosmarus Quagga optimized explainable generative meta learning based deep convolutional neural network model.

PURPOSE: Non-Proliferative Diabetic Retinopathy (NPDR) is a complication of diabetes disease where t...

Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century.

Since the turn of the millennium, computational modelling of biological systems has evolved remarkab...

Deep learning-based evaluation of the severity of mitral regurgitation in canine myxomatous mitral valve disease patients using digital stethoscope recordings.

BACKGROUND: Myxomatous mitral valve disease (MMVD) represents the most prevalent cardiac disorder in...

Physics-Informed Machine Learning for Fast Screening High Hydrogen Storage MOFs with Monotonicity Constraints.

Hydrogen represents a highly promising alternative energy vehicle that facilitates the transition to...

Association of Physical Activity from Wearable Devices and Chronic Disease Risk: Insights from the All of Us Research Program.

Physical activity is a modifiable factor influencing chronic disease risk. Previous studies often re...