Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Bump2Baby & Me+ (B2B&Me+): Protocol for a multi-country, European implementation project to reduce the incidence of gestational diabetes mellitus and improve maternal and child health

Background Gestational diabetes mellitus (GDM) affects 1-in-7 pregnancies globally and is associated with significant short- and long-term health consequences. Although health behaviour change interventions can effectively reduce these risks, a significant implementation gap exists in translating this evidence into routine practice. Bump2Baby and Me (B2B&Me) was a mobile health (mHealth) coaching ...

NVAITC AI Scientist: A Governed End-to-End Research System -- A Hypertension GWAS Case Study

Agentic research systems are emerging as a new paradigm for coordinating scientific workflows beyond isolated model inference, code generation, or statistical analysis. However, deployment in institutional biomedical environments requires governed mechanisms for research planning, data access, workflow orchestration, evidence tracking, reproducibility, and human oversight. We present NVAITC AI Sci...

Jul 13 2026 2607.11084v1
Longitudinal Multi-View Breast Cancer Risk Prediction

Accurate breast cancer risk prediction from screening mammography is critical for enabling personalized screening intervals and early detection. Recen...

Jul 13 2026 2607.11343v1
RadGuide AI: Development and Technical Evaluation of a General Nuclear Medicine Agent for Traceable Radiopharmaceutical Decision Support

Background: Nuclear medicine and radiopharmaceutical development require coordinated radiochemistry, dosimetry, molecular imaging, radiation-safety an...

Effect of initiating an ARB- versus ACEI-based regimen on dementia risk, a target trial emulation of 2.5 million US Veterans

Background: Hypertension is a modifiable risk factor for dementia, yet the comparative effectiveness of angiotensin receptor blockers (ARBs) versus an...

A large language model-assisted workflow for generating a living evidence base for climate-sensitive foodborne disease

Abstract Climate change is altering environmental conditions that influence foodborne disease transmission, yet traditional systematic reviews cannot ...

Generative Drug Design in a Loop with dtSFM

Directed evolution consisting of iterative rounds of diversification, selection, and counter-selection, underlies modern protein and antibody engineer...

Emergency Department Presenting Concerns Among Admissions With Hypercapnia: A Retrospective NLP Study of MIMIC-IV

Background Hypercapnia may indicate a primary ventilatory syndrome, a complication of another illness, or an epiphenomenon of severe disease. The pres...

Association of Lacunes with Risk Factors, Cognition, and Atrophy: The Multi-Ethnic Study of Atherosclerosis (MESA)

Abstract Background: Lacunes are 3-15 mm cavities originating from small perforating artery disease and are a hallmark of cerebral small vessel diseas...

Cross-Domain Knowledge Transfer from Expert-Annotated Gated CT via Synthetic Ungated CT Improves Coronary Artery Calcium Scoring on CT Attenuation Correction Scans

Background: Coronary artery calcium (CAC) is an established measure of coronary atherosclerosis from computed tomography (CT). While deep learning (DL...

Association between glycated hemoglobin A1c and automated abdominal aortic calcification: the UK Biobank Imaging Study

Background: Poor glycemic control is associated with cardiovascular disease (CVD) risk. However, it is unknown whether glycemic control is related to ...

Machine Learning for Depression Screening and Intervention: an Original Circadian Rhythm Score-based Methodology

Depression screening from large-scale behavioral data is challenged by fragmented circadian indicators, limited interpretability, and the lack of inte...

Jul 6 2026 2607.04648v1
Correct but Slow: An Empirical Study of the GPU Kernel Evaluation Gap in Modern Domain-Specific Languages

Modern GPU domain-specific languages (DSLs), such as Triton and TileLang, are increasingly used to implement specialized deep-learning kernels and as ...

Jul 5 2026 2607.04454v1
Integrative analysis of cfDNA features from ultra-low coverage whole genome sequencing enables robust detection of ovarian cancer

Background: Despite advances in circulating tumor DNA analysis, reliable detection of oncological disease from ultra-low coverage whole genome sequenc...

Artificial intelligence virtual cell immune recovery model for screening traditional Chinese medicine ingredients

Screening therapeutic candidates from single-cell transcriptomes requires a target that is closer to treatment response than disease-signature reversa...

Comparing Artificial Intelligence versus Human Screening in Systematic Reviews

Introduction. Systematic reviews are essential for informing health policy and practice. Artificial intelligence (AI) automates the article screening ...

A foundation model of wearable pulse oximetry reveals physiological signatures of health and cardiometabolic risk

While Photoplethysmography (PPG) is established as a noninvasive optical tool for monitoring heart rate and oxygen saturation, its high-resolution blo...

NeuroBridge: Bridging Multi-Task MRI Knowledge for Neurodegenerative Disease Diagnosis

INTRODUCTION: Accurate MRI-based identification of Alzheimer's disease (AD), mild cognitive impairment (MCI), and related dementias remains challengin...

Jul 1 2026 2607.01401v1
SubGaitNet: A Decision-Oriented and Interpretable AI Framework for Robust GRF-Based Gait Assessment in Neurological and Musculoskeletal Care

Ground reaction force (GRF)-based gait analysis provides objective, non-invasive evidence for neurological and musculoskeletal assessment, but its tra...

RESCUE: An end-to-end multi-agent LLM system for proactive rare-disease patient screening in the EHR

Background: Rare diseases affect a significant portion of the global population, yet patients often endure a lengthy diagnostic odyssey, frequently mi...

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