Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Survival Meets Classification: A Novel Framework for Early Risk Prediction Models of Chronic Diseases

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and chronic ischemic heart disease. In this study, we present a novel approach for disease risk models by integrating survival analysis with classification techniques. Tr...

Mar 12 2026 2603.11598v1

Cough activity detection for automatic tuberculosis screening

The automatic identification of cough segments in audio through the determination of start and end points is pivotal to building scalable screening tools in health technologies for pulmonary related diseases. We propose the application of two current pre-trained architectures to the task of cough activity detection. A dataset of recordings containing cough from patients symptomatic for tuberculosi...

Mar 11 2026 2603.11241v1
Co-designing a virtual reality based mindfulness application to address diabetes distress using Artificial Intelligence-informed Experience-Based Co-Design (AI-EBCD): a feasibility study

More than one third of adults with diabetes can experience diabetes distress due to the demands of daily self-care. As a cognitive therapy, mindfulnes...

Regression vs. Medical LLMs: A Comprehensive Study for CVD and Mortality Risk Prediction

Cardiovascular diseases (CVDs) remain the foremost cause of global morbidity and mortality, driving an urgent need for robust predictive tools that en...

Identification and Developmental Analysis of the Facial Characteristics Associated with Sickle Cell Disease using Machine Learning

Background Sickle cell disease (SCD) is a common inherited genetic disorder and contributor to global childhood mortality and morbidity. In the Democr...

Association of Radiologic PPFE Change with Mortality in Lung Cancer Screening Cohorts

Background: Pleuroparenchymal fibroelastosis (PPFE) is an upper lobe predominant fibrotic lung abnormality associated with increased mortality in esta...

Mar 10 2026 2603.09531v1
Impact of Image Bit Depth Reduction on Deep Learning Performance in Chest Radiograph Analysis: A Multi-institutional Study

Purpose Medical imaging typically generates 12- to 16-bit formats, yet conversion to 8-bit is often required. While deep learning has been widely expl...

Sex-stratified Integrated Analysis of US lung Cancer Mortality, 1994-2020

Importance: Lung cancer mortality in the United States has fallen substantially in recent decades, yet the relative influence of behavioral, environme...

Improving the detection of clinically significant steatotic liver disease using a machine learning algorithm in a real-world primary care population

Background and aims Population screening for liver disease in high-risk groups is recommended. Community diagnosis of liver disease is a challenge due...

Enhancing Prediabetes Diagnosis from Continuous Glucose Monitoring Data via Iterative Label Cleaning and Deep Learning

As of early 2026, over 115 million US adults (more than 1 in 3) have prediabetes, a condition with an annual conversion rate of 5%-10% to type 2 diabe...

Uncertainty-aware Blood Glucose Prediction from Continuous Glucose Monitoring Data

In this work, we investigate uncertainty-aware neural network models for blood glucose prediction and adverse glycemic event identification in Type 1 ...

Mar 5 2026 2603.04955v1
Perceptions of Artificial Intelligence in the Editorial and Peer Review Process: A Cross-Sectional Survey of Traditional, Complementary, and Integrative Medicine Journal Editors

Background: Artificial intelligence chatbots (AICs) are increasingly being integrated into scholarly publishing, with the potential to automate routin...

Evaluating a Locally Deployed 20-Billion Parameter Large Language Model for Automated Abstract Screening in Systematic Reviews

Abstract Background: Systematic reviews (SRs) are essential for evidence-based medicine but require extensive time and resources for abstract screenin...

Longitudinal Impact of NLP-Augmented Clinical Decision Support on Cognitive Decline Detection in German Geriatric Primary Care: A Dynamic Panel Data Analysis Using System GMM Estimation

Background: Cognitive decline and dementia represent major public health challenges in aging populations. Natural language processing (NLP)-augmented ...

Design and Rationale of the My Heart Counts Cardiovascular Health Study: a Large-Scale, Fully Digital Biobank, and Randomized Trial of Large Language Model-Driven Coaching of Physical Activity

Background: Cardiovascular disease remains the leading cause of global morbidity and mortality. The original My Heart Counts smartphone application de...

GEN-KnowRD: Reframing AI for Rare Disease Recognition

Rare diseases affect over 300 million people worldwide, yet patients often endure years-long diagnostic delays that limit timely intervention and tria...

CausalFund: Causality-Inspired Domain Generalization in Retinal Fundus Imaging for Low-Resource Screening

Early screening for glaucoma and diabetic retinopathy (DR) is critical to prevent irreversible vision loss, yet remains inaccessible to many underserv...

Evaluating Few-Shot Meta-Learning using STUNT for Microbiome-Based Disease Classification

The human gut microbiome is increasingly explored as a diagnostic indicator for disease, yet machine learning models trained on metagenomic data are o...

Evaluating AI-Assisted Customer Verification for Synthetic Nucleic Acid Screening

Legitimacy screening, the process of verifying the identity and purpose of customers ordering synthetic nucleic acids, is a primary safeguard against ...

Operationalizing Longitudinal Causal Discovery Under Real-World Workflow Constraints

Causal discovery has achieved substantial theoretical progress, yet its deployment in large-scale longitudinal systems remains limited. A key obstacle...

Feb 27 2026 2602.23800v1
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