Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Large Language Models for Endodontic Symptom Assessment and Treatment Planning Using Image-Free Clinical Records: Comparative Evaluation Study.

BACKGROUND: Accurate assessment of pulpal status is essential for achieving successful endodontic ou...

Jul 2026 42497401
Noninvasive diabetes mellitus classification based on HbA1c using the mel-frequency cepstral coefficients from the photoplethysmographic signal.

Diabetes mellitus (DM) is a metabolic condition with improper regulation of blood sugar levels a...

Jul 2026 42497900
Development and validation of an interpretable machine learning model for predicting hypertension risk in patients with psoriasis.

OBJECTIVE: Hypertension is a common yet frequently underdiagnosed comorbidity in psoriasis patients....

(5)
Jul 2026 42502685
Classifying Diabetic and Healthy β-Cells in Type 2 Diabetes Using Machine Learning on Single-Cell RNA Sequencing Data.

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to impai...

(2)
Jul 2026 42500329
Research advances in key genes and regulatory mechanisms of posttranslational modifications in Parkinson's disease.

BACKGROUND: The genesis of Parkinson's disease (PD), a common central neurodegenerative disorder, in...

(3)
Jul 2026 42497137
Artificial Intelligence and Generative Models in Hepatology: From Large Language Models to Digital Pathology in Liver Disease Diagnosis and Treatment.

Artificial intelligence (AI), particularly foundation and generative models, is reshaping the practi...

(1)
Jul 2026 42487578
Artificial intelligence-augmented organ- and organoid-on-a-chip for drug screening.

Organ- and organoid-on-a-chip technologies provide critical human-relevant models for drug screening...

Jul 2026 42489060
The mediating role of genes in the influence of intestinal flora on type 2 diabetes and the screening of diagnostic markers.

INTRODUCTION: The composition of intestinal flora affects the occurrence and development of type 2 d...

Jul 2026 42489317
Large-Scale Plasma Proteomics Profiles for Predicting Atrial Fibrillation Associated Stroke Risk : Type of manuscript: Original Research.

BACKGROUND: Stroke is a major complication of atrial fibrillation (AF), and risk prediction using th...

(2)
Jul 2026 42489810
Large language models as a screening tool for the qualification of patients with Parkinson's disease for device-aided therapies.

Motor complications become increasingly prominent as Parkinson's disease (PD) progresses. Although d...

(4)
Jul 2026 42489906
Zebrafish as a versatile model in biomedical research, from disease modeling to regenerative medicine: a review.

Zebrafish are an effective animal model widely utilized in biomedical research. They are known for t...

(1)
Jul 2026 42489951
DeorphaNN: Virtual screening of GPCR peptide agonists using AlphaFold-predicted active-state complexes and deep learning embeddings.

Peptide-activated G protein-coupled receptors (GPCRs) regulate physiological processes through inter...

Jul 2026 42492505
Myocardial Native T1 Mapping in the German National Cohort (NAKO): Associations with Age, Sex, and Cardiometabolic Risk Factors.

BACKGROUND: In cardiovascular magnetic resonance (CMR), myocardial native T1 mapping enables quantit...

(1)
Jul 2026 42492816
Bridging Audience Segmentation and Message Intervention: AI-Generated HBM-Based Messages for Diabetes Prevention.

Health communication often faces a segmentation-intervention gap: psychographic segmentation identif...

Jul 2026 42493759
ANGPTL4 in gestational diabetes: a diagnostic biomarker linked to placental senescence.

Current diagnostic methods for Gestational Diabetes Mellitus (GDM) inadequately reflect early placen...

Jul 2026 42487020
Digital phenotyping of CGM engagement reveals distinct glycemic outcomes.

Benefits from continuous glucose monitors (CGMs) may depend on how devices are used over time-not on...

Jul 2026 42490562
Mol2Image: an enhanced DDI prediction framework leveraging drug molecular descriptors.

Drug-drug interactions (DDIs) are a critical safety issue in clinical practice, as they can lead to ...

Jul 2026 42493778
AI interventions in cancer screening: balancing equity and cost-effectiveness.

This paper examines the integration of artificial intelligence (AI) into cancer screening programmes...

(2)
Jul 2026 40295097
Hypertension-associated DNA methylation signatures and multi-generational epigenetic clocks in Korean adults.

Hypertension is a hallmark of vascular aging; however, the epigenetic link between biological aging ...

(2)
Jul 2026 42481862
AI-based Synthetic CT Angiography from Non-contrast CT for Cerebrovascular Disease Screening.

BACKGROUND: CT angiography (CTA) is a key investigation in cerebrovascular disease. However, CTA is ...

(8)
Jul 2026 42483869
Effect of cataracts on systemic factor prediction from fundus images.

OBJECTIVE: To evaluate the effect of cataracts on systemic factor predictions from fundus images by ...

(4)
Jul 2026 42484678
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