Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Showing 821-840 of 17,188 articles

Performance evaluation of deep learning based YOLOv5 and YOLOv8 models for real time breast cancer detection in mammographic images.

Breast cancer detection remains a significant challenge in medical diagnostics. Traditional diagnostic methods are time-consuming, unable to detect complex patterns in medical images, and achieve only moderate accuracy with high false-positive rates. The study aims to identify the most effective and efficient algorithm for clinical application that reduces the rates of false positives and false ne...

Jun 10 2026 42268482

Multi-Omics Integration Reveals the Genetic Mechanisms of Periodontitis and Predicts Therapeutic Drugs.

BACKGROUND: Periodontitis is a chronic inflammatory disease driven by host immune dysregulation. However, the specific genetic regulatory mechanisms underlying this disease remain unclear. Identifying key molecular targets is crucial for precise therapeutic intervention. METHODS: This study integrated genome-wide association study (GWAS) summary statistics from the Gene-Lifestyle Interactions in D...

Jun 10 2026 42269280
From DNA to Drug Discovery AI Models for Cardiovascular Precision Medicine.

Cardiovascular diseases remain the world's leading cause of death-yet the molecular mechanisms linking genetic variation to clinical outcomes are stil...

Jun 10 2026 42269859
Prospective validation of an AI algorithm to identify adult-onset type 1 diabetes misclassification: protocol for a non-interventional multicentre study.

INTRODUCTION: Adult-onset type 1 diabetes (T1D) is often misclassified as type 2 diabetes (T2D), resulting in delayed treatment, missed opportunities ...

Jun 10 2026 42270100
Dementia transition in early cognitive decline trajectories (DETECT) study: a prospective longitudinal study protocol.

BACKGROUND: Mild cognitive impairment is widely recognized as a high-risk state associated with a progression to dementia. Although previous studies h...

Jun 9 2026 42265623
A Novel Blood-Based Screening Test for Colorectal Cancer Using Raman Spectroscopy.

BACKGROUND: Label-free vibrational spectroscopic techniques (Raman spectroscopy) combined with machine learning (ML) methodologies have huge potential...

Jun 9 2026 42265893
Comparing supervised machine learning and large language models in title-abstract screening.

BACKGROUND: Systematic reviews require reviewers to decide on the eligibility of large numbers of articles derived from database searches. To accelera...

Jun 9 2026 42260611
Exploratory Evaluation of Dual Digital Platforms for Acute Brain Conditions in Medically Underserved Rural Areas : A Chuncheon, Gangwon-do Experience.

OBJECTIVE: To describe an exploratory initial experience with two complementary digital platforms consisting of an AI-based telemedicine system and an...

Jun 9 2026 42261217
Evolution of Chatbots as an Educational and Supportive Digital Intervention for Family Caregivers of People With Dementia: Protocol for a Systematic Integrative Review.

BACKGROUND: Most people with dementia reside in the community and are cared for by family members. Family caregivers play an essential role in support...

Jun 9 2026 42262014
The Implementation of a Business Process Model and Notation for Modeling Patient Health Care Trajectories: Systematic Review.

BACKGROUND: Health care systems are increasingly confronted with the challenge of managing complex clinical processes. One proposed solution is a pati...

Jun 9 2026 42263138
Graph neural networks for networked analysis of gestational diabetes risk factors: a multi method framework.

Gestational diabetes mellitus, often known as GDM, is a major health issue that causes complications for mothers and requires patient data prediction ...

Jun 9 2026 42259874
Decision tree with randomized grid search-based hyperparameter tuning and optimal feature scaling for diabetes diagnosis.

BACKGROUND: Diabetes is a chronic condition that arises when the body cannot effectively regulate blood glucose levels, either due to insufficient ins...

Jun 8 2026 42260338
Development and Validation of a Novel Risk Prediction Model for Incident Diabetic Foot Complications: A Large, Longitudinal, Population-Based Machine Learning Study.

OBJECTIVE: Diabetic foot complications (DFCs) are common diabetes complications. Existing tools for predicting incident DFCs remain insufficient. This...

Jun 8 2026 42253099
Pancreatic Cancer Risk Stratification Across Diabetes Stages: Development and Internal Validation of a Machine Learning Model.

BACKGROUND: Pancreatic cancer is diagnosed at advanced stages in diabetes patients. Existing prediction models require complete historical data and fo...

Jun 8 2026 42257579
Development of a machine learning model using systemic and ophthalmic parameters to detect sleep-disordered breathing in glaucoma patients.

PURPOSE: To develop and validate a machine-learning model using systemic and ophthalmic parameters that predicts sleep-disordered breathing (SDB) in p...

Jun 8 2026 42257836
Unique Digital Images as Incentives in Clinical Trials: A Digital Shift Toward Meaningful Participation.

Incentivization in clinical trial participation can be challenging, with many studies failing to meet recruitment or retention goals despite tradition...

Jun 8 2026 42258364
The emerging role of coronary computed tomography for prevention of cardiovascular disease in asymptomatic individuals.

The persistent global rise in atherosclerotic cardiovascular disease (ASCVD) challenges the effectiveness of current risk factor-based algorithms in p...

Jun 8 2026 42258629
Classification of glucose profile in Japanese patients with type 1 diabetes and its association with complications.

CONTEXT: The importance of utilizing continuous glucose monitoring (CGM) to optimize glycemic profiles and thereby prevent the onset of diabetic compl...

Jun 8 2026 42258635
Digital service innovation for climate-resilient urban pavements: Decision-as-a-service linking UHI-aware ML to environmental-economic performance.

Cities increasingly require digital services that convert urban climate signals into maintenance decisions with measurable environmental and economic ...

Jun 8 2026 42259037
Combining artificial intelligence analysis with expert mammogram reading: Determining the optimal AI positivity cut-off point for the French population-based breast cancer screening program.

PURPOSE: Artificial intelligence (AI) is increasingly explored as a complement to radiologists in population-based breast cancer screening, yet optima...

Jun 8 2026 42259109
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