Latest AI and machine learning research in primary care for healthcare professionals.
Glioblastoma multiforme (GBM) is an aggressive primary brain tumour that presents significant treatment challenges due to its complex pathology and heterogeneity. The lack of validated molecular targets is a major obstacle for discovering new therapeutic candidates, with no new effective GBM therapies delivered to patients in over two decades. Here, we report the identification of compounds that t...
AIMS: Heart failure is prevalent; however, there is no cost-effective screening option. Against formal echocardiography, we assessed the diagnostic performance of focused cardiac ultrasound (FoCUS), performed by novice users guided and interpreted by artificial intelligence (AI) for the assessment of left ventricular ejection fraction (LVEF). METHODS AND RESULTS: We prospectively enrolled 496 adul...
BACKGROUND: Despite advanced analytical methods and increasing data availability, most intensive care unit (ICU) prediction models rely on static meas...
AimsDiabetes mellitus is a global health challenge requiring innovative solutions for early diagnosis, personalized treatment, and ongoing management....
BACKGROUND: Kikuchi disease, lymphoma, lymphadenitis, and tuberculosis are common diseases affecting the head and neck. The causes and treatment metho...
The modernization of Traditional Chinese Medicine (TCM) faces considerable challenges, primarily due to the poor water solubility, low chemical stabil...
BACKGROUND: The demand for total hip arthroplasty (THA) is increasing, yet disparities in access and outcomes persist across racial, ethnic, and socio...
AIMS: This study aimed to develop a machine learning model for predicting chronic osteomyelitis recurrence (COR) following the Masquelet technique (MT...
Purpose To evaluate the performance of an artificial intelligence (AI) model for digital breast tomosynthesis (DBT) with and without prior screening e...
PURPOSE OF REVIEW: Structural heart disease (SHD) encompasses diseases involving the heart valves, chambers, walls, and muscles. Current diagnostic me...
Diabetic foot ulcers are serious skin wounds that affect many people with diabetes, often leading to severe infections or even the loss of a limb. Thi...
BACKGROUND: Older adults facing social or structural marginalization for reasons such as lower literacy, digital exclusion, financial constraints, res...
Health informatics and artificial intelligence (AI) technologies are increasingly influencing pediatric health care delivery across diverse health sys...
OBJECTIVE: This study aimed to examine the interaction patterns between the reward and inhibitory control systems in children with overweight and obes...
BACKGROUND: Diabetic foot ulcers (DFUs) represent a severe chronic complication of diabetes and are characterized by persistent impairment of wound he...
BACKGROUND: The gut microbiota adapts to and shapes the host's metabolic state through affecting circulating metabolites and consequent gene regulator...
Directed evolution has become a central methodology for engineering proteins with improved or entirely new functions, enabling applications across bio...
Hypertension is a modifiable risk factor for cardiovascular disease (CVD) and its prevalence is high in the United States and worldwide. Adequate char...
BACKGROUND: Non-invasive biomarkers with biological rationale are needed for identifying patients with progressive metabolic dysfunction-associated st...
BACKGROUND: Type 1 Diabetes Mellitus (T1D) has been increasingly associated with alterations in the gut microbiome. However, the impact of taxonomic r...