Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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60 kVp Coronary CT Angiography as a Screening Tool on Asymptomatic Patients: An Initial Experience.

PURPOSE: To investigate the feasibility of using 60 kVp coronary CT angiography (CCTA) combined with deep learning-based CT reconstruction as a screening tool on asymptomatic patients. MATERIALS AND METHODS: A total of 156 asymptomatic patients (body mass index, 24.4 ± 2.2 kg/m 2 ) with at least one coronary artery disease (CAD) risk factor were prospectively enrolled for taking an experimental ul...

May 1 2026 41363201

IN-HUMAN FEASIBILITY AND SAFETY OF SUBRETINAL DRUG INJECTION THROUGH ATTACHED RETINA USING A ROBOTIC COMANIPULATION SYSTEM.

PURPOSE: To evaluate feasibility and safety of robot-assisted subretinal injections through attached retina using the comanipulated Mynutia system in patients with submacular hemorrhage. METHODS: This prospective, single-center case series included 20 eyes undergoing vitrectomy with subretinal recombinant tissue plasminogen activator between June 2024 and August 2025. The EVA Inicio microinjection...

May 1 2026 41533897
Interactive active learning for literature screening: finetuning GPT with DeepSeek reasoning for cross-domain generalization.

OBJECTIVE: Automated literature screening in biomedical research is often hindered by domain shifts and scarcity of labeled data, which limit model ac...

May 1 2026 41801982
Classifying Kidney Tumor via Adaptive SE-ResNeXt With Mutli-Novel Loss Function and Renal Mass Segmentation Using Pyramidal Attention-Based R2Unet++ Model.

Kidney tumors are one of the prevalent types of tumor globally and it has become a significant health concern. It is the most frequent type of urologi...

May 1 2026 42043283
Hypoglycaemia Risk Prediction Models for Type 2 Diabetes: A Systematic Review and Meta-Analysis.

BACKGROUND: The growing number of hypoglycaemia risk prediction models for Type 2 diabetes mellitus (T2DM) underscores the need for systematic evaluat...

May 1 2026 42051120
Trends in accuracy management of continuous glucose monitoring systems.

Continuous glucose monitoring (CGM) has markedly advanced diabetes care by enabling real-time visualization of glycaemic variability, prevention of hy...

Apr 30 2026 42078491
Automated approaches to identifying clinical trials based on title and abstract in the field of physiotherapy: a comparative analysis.

OBJECTIVE: To compare accuracy, precision, recall, F1 and time spent using commercial tools to identify physiotherapy trials based on title and abstra...

Apr 30 2026 42069070
Artificial intelligence-driven early screening and diagnosis of pancreatic cancer: technical innovations, clinical applications, and precision medicine strategies.

BACKGROUND: Pancreatic cancer is characterized by prolonged subclinical progression, molecular heterogeneity, and late clinical presentation, resultin...

Apr 30 2026 42069141
Machine learning-enhanced plasma proteomics discriminates pancreatic cancer-associated diabetes from type 2 diabetes mellitus.

Pancreatic ductal adenocarcinoma (PDAC) is frequently preceded by new-onset diabetes mellitus (NODM), yet differentiating PDAC-associated DM from type...

Apr 30 2026 42069247
Empowering atrial fibrillation detection with TabPFN and SHAP interpretation based on ECG-derived features: a dual-center temporal validation study.

Atrial fibrillation (AF) remains a leading driver of stroke and heart failure, yet timely diagnosis is frequently hindered by its asymptomatic nature ...

Apr 30 2026 42062911
Explainable prediction of MDR/RR-TB in tuberculosis-diabetes mellitus multimorbidity: a machine learning model developed and validated in a dual-center study.

BACKGROUND: Tuberculosis-diabetes mellitus (TB-DM) multimorbidity significantly increases the risk of multidrug-resistant/rifampicin-resistant tubercu...

Apr 30 2026 42062970
Revolutionizing lung cancer screening: the rise of artificial intelligence integrating circulating tumor markers.

Lung cancer persists as the predominant oncological cause of mortality globally, underscoring an imperative public health issue that demands effective...

Apr 30 2026 42063042
AI-based knee osteoarthritis progression prediction: a comprehensive global bibliometric and hotspot evolution analysis (2010-2025).

BACKGROUND: Knee osteoarthritis (OA) is a leading global cause of disability, yet conventional tools lack sensitivity for early detection and precise ...

Apr 30 2026 42063116
Discovering non-linear dynamics of miRNAs in Alzheimer's disease-related cognitive impairment: a cross-species approach with explainable machine learning.

BACKGROUND: MicroRNA (miRNA) biomarker studies in Alzheimer's disease (AD) typically assume monotonic relationships between expression levels and dise...

Apr 30 2026 42063169
A scoping review of quality prescribing indicators, rules and criteria for primary care.

Medication-related problems (MRPs) place a substantial burden on the healthcare system, contributing to hospital admissions and significant healthcare...

Apr 30 2026 42063282
CT-based body composition and its change through time in relation to outcomes in participants screened for lung cancer.

BACKGROUND: Computed Tomography (CT) scans allow opportunistic evaluation of body composition. We investigated whether body composition and change thr...

Apr 30 2026 42066437
Malignant Transformation Risk in Patients With Oral Leukoplakia and Type 2 Diabetes Mellitus.

INTRODUCTION AND AIMS: Oral leukoplakia (OLK) is the most common oral potentially malignant disorder, with a malignant transformation rate of up to 9....

Apr 30 2026 42066493
Time-Dynamic AI Models to Predict Quality of Life in Patients With Breast Cancer: Development and Validation Study Using the EORTC BALANCE Cohort.

BACKGROUND: Patients with breast cancer often experience health-related quality of life (HRQoL) impairments that remain difficult to predict on an ind...

Apr 30 2026 42060909
Genetic association and machine learning improve the prediction of type 1 diabetes risk.

Type 1 diabetes (T1D) has a large genetic component, and expanded genetic studies of T1D can enhance biological and therapeutic discovery and improve ...

Apr 30 2026 42062540
Data-driven prioritization of high-risk individuals for weight loss interventions.

New obesity medications have demonstrated efficacy in trials, but their real-world deployment is partly limited by the absence of approaches that iden...

Apr 30 2026 42062622
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