Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Coronary artery calcium score - emerging role for opportunistic screening and novel applications.

Coronary artery calcium (CAC) can be identified on thoracic CT performed for a variety of clinical indications, including routine thoracic CT, lung cancer screening CT and attenuation correction CT. Identification of CAC on thoracic CT as part of opportunistic screening can improve the assessment of cardiovascular risk and can identify patients who may benefit from preventative medical therapies. ...

Apr 25 2026 42033770

Tech That Scales: A Practical Framework for Artificial Intelligence-Enabled Cancer Care in Low- and Middle-Income Countries and Underserved US Counties.

Cancer outcomes remain starkly unequal: 5-year survival rates for common malignancies in low- and middle-income countries (LMICs) often lag 20-40 percentage points behind high-income benchmarks, and similar disparities persist between well-resourced metropolitan centers and rural or safety-net settings within high-income countries. The gap is driven less by the absence of effective interventions t...

Apr 24 2026 42030499
Prediction of trajectories and outcomes in early-stage metabolic dysfunction-associated steatotic liver disease: a narrative review.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disorder, with manifestations ranging from steato...

Apr 24 2026 42065100
External Validation of the PIPRA Model for Postoperative Delirium Prediction in a Japanese ICU Cohort: Integrating AI-Based Risk Assessment into Perioperative Care.

BACKGROUND: Postoperative delirium (POD) is a prevalent and serious complication in older surgical patients, linked to prolonged hospitalization, high...

Apr 24 2026 42035932
A Novel Breast Arterial Calcification Age-Based Percentile Nomogram for the Incremental Prediction of Incidental Cardiovascular Events.

BACKGROUND: Breast arterial calcification (BAC) detected on routine mammography is an emerging marker of cardiovascular risk in women. However, substa...

Apr 24 2026 42033436
An interpretable machine learning model for predicting stroke in patients with hypertension: insights from the SPRINT.

Stroke is a leading cause of mortality worldwide, with hypertension being its most significant risk factor. However, few studies have specifically dev...

Apr 24 2026 42031951
Chemical contaminants and fish: implications for health and ecosystem sustainability.

Chemical pollutants in aquatic ecosystems pose a significant and growing threat to fish health and overall ecosystem sustainability. This review highl...

Apr 24 2026 42032415
Artificial intelligence for early detection of aortic stenosis: The emerging role of NPs.

Aortic stenosis is associated with significant morbidity and mortality if left untreated. Nurse practitioners in primary care are uniquely positioned ...

Apr 23 2026 42021009
Adapting the REVEAL Lite 2 score to the pediatric population through machine learning: insights from the REHIPED registry for pediatric pulmonary hypertension.

INTRODUCTION AND OBJECTIVES: Risk scores for pulmonary hypertension (PH) have been proven useful in adults. However, no risk score has been validated ...

Apr 23 2026 42034336
Optimizing Timeliness of Healthcare Delivery in Diagnostic Radiology at U.S. Academic Centers.

RATIONALE AND OBJECTIVES: Timely radiology access is essential for accurate diagnosis, treatment planning, and efficient care delivery. U.S. academic ...

Apr 23 2026 42031598
Empowering Patients and Clinicians: LLMs in Hypertension Care: A Scoping Review.

Large language models have emerged as potential tools to support hypertension care, including diagnosis, treatment decision-making, and patient educat...

Apr 23 2026 42021742
Machine Learning Analysis of Serum Metabolomics for Multi-Disease Classification and Proteome-Metabolome Pathway Insights in T2D, IBD, and CRC.

Type 2 diabetes (T2D), inflammatory bowel disease (IBD), and colorectal cancer (CRC) share overlapping metabolic alterations that hinder early, diseas...

Apr 23 2026 42024141
A structure-based virtual screening approach to identify novel anaplastic lymphoma kinase inhibitors.

CONTEXT: Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that plays a crucial role in cellular signaling and is implicated in several c...

Apr 23 2026 42024204
Unsupervised Agglomerative Cluster Phenotyping of Young Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.

BACKGROUND: Young patients with acute coronary syndrome (ACS) exhibit diverse demographic, clinical and angiographic characteristics. We hypothesized ...

Apr 23 2026 42026648
Segmentation for pelvic malignancies in radiation oncology practice: a systematic review and meta-analysis protocol.

BACKGROUND: Deep learning (DL)-based artificial intelligence (AI) models, the fourth generation in autosegmentation, have been adopted both for commer...

Apr 23 2026 42026695
Screening of metabolic-related biomarkers linking intervertebral disc degeneration and type 2 diabetes based on comprehensive bioinformatics analysis and machine learning.

BACKGROUND: Intervertebral disc degeneration (IVDD) is a prominent etiology of lower back pain. Type 2 diabetes (T2D), the most prevalent metabolic di...

Apr 22 2026 42064579
Precision nutrition in breast cancer: Towards patient- and tumour-informed dietary strategies.

Dietary strategies are increasingly recognized as important modulators of breast cancer outcomes, acting through effects on metabolic regulation, weig...

Apr 22 2026 42096978
Monitoring airline pilot mental health: a 3PM framework utilising digital phenotyping and AI.

The aeromedical certification of commercial airline pilots relies on periodic, self-disclosure-dependent assessments. However, this reactive model lac...

Apr 22 2026 42179459
Modelling the epidemic dynamics of HPV among women in China and optimization of ongoing cervical cancer elimination strategies.

BACKGROUND: The infection of high-risk human papillomavirus (hr-HPV) and related cervical cancer have greatly threatened women's health. However, the ...

Apr 22 2026 42021319
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