Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Application of machine learning in osteoporosis screening: a narrative review.

Machine learning has the potential to address limitations of traditional osteoporosis screening through advanced data processing and pattern recognition capabilities. This review provides a critical analysis of ML applications in opportunistic screening, precision risk assessment, and quantitative bone quality analysis, while addressing current implementation challenges and future research directi...

Apr 11 2026 41965453

ChatGPT for obesity management: a review of evidence, potential challenges, and clinical implications.

The global rise in the prevalence of obesity highlights the need for accessible and effective solutions for obesity management. ChatGPT, one of the fastest-growing artificial intelligence (AI) tools, is gaining attention for its potential to offer interactive support in managing complex conditions such as obesity. In this Review, we used a thematic synthesis approach to examine ChatGPT's effect on...

Apr 10 2026 41966942
Embedded AI-Assisted Otoscopic Image Screening for Pediatric Otitis Media.

OBJECTIVE: To evaluate an embedded artificial intelligence (AI) system for otoscopic image-based screening and prediagnostic triage of pediatric otiti...

Apr 10 2026 41964158
AI in Oral Health Surveillance: Critical Review.

Artificial intelligence (AI) holds transformative potential for advancing oral health surveillance by streamlining data collection, integration, and d...

Apr 10 2026 41958249
Glycation and disease: a systematic review of the analytical methods and applications of advanced glycation end products (AGEs) as biomarkers of disease.

Over a century since Louis Camille Maillard first described the reaction that bears his name, advanced glycation end products (AGEs) resulting from th...

Apr 10 2026 41961903
Exposome-wide patterns predict brain health in aging.

Promoting brain health is vital for well-being and reducing healthcare burdens. Brain health as measured with the Brain Age Gap (BAG) - the difference...

Apr 10 2026 41963296
Advanced machine learning-guided optimization platform for high-yield soluble expression of Pseudomonas aeruginosa exotoxin A in engineered Escherichia coli strains.

BACKGROUND: The recombinant production of Pseudomonas aeruginosa exotoxin A (ETA), a critical component for immunotoxin development, remains hindered ...

Apr 10 2026 41961866
Multivariate machine learning regression approaches to predict adolescent suicide risk.

BACKGROUND: Suicide is a leading cause of death among adolescents, yet most prediction models rely on binary classification and limited predictors, fa...

Apr 9 2026 41990521
Regulatory risk loci link disrupted androgen response to the pathophysiology of polycystic ovary syndrome.

A major challenge in deciphering the complex genetic landscape of polycystic ovary syndrome (PCOS) lies in the limited understanding of how susceptibi...

Apr 9 2026 41994484
Enhanced glucose forecasting using recurrent neural network and advanced feature engineering.

The aim of this study is to develop an artificial intelligence (AI)-driven pipeline for forecasting blood glucose levels to mitigate risks associated ...

Apr 9 2026 41957441
High-Throughput Screening for Ageing and Age-Related Disease Drug Discovery: Advances and Challenges.

Ageing is the primary risk factor for many chronic, degenerative, and life-threatening disorders, yet the translational pipeline for geroprotective in...

Apr 9 2026 41966413
Self-enhancement-based perfusion mapping with contrast-enhanced magnetic resonance imaging for PAD assessment.

We developed an automatic self-enhancement-based perfusion mapping (SEPM) method to relatively map the microvascular perfusion level in contrast-enhan...

Apr 9 2026 41966496
Thrombosis after surgical splenectomy - why, in whom and can we prevent it?

Splenectomy remains a common operation performed in the setting of trauma, haematological disease, malignancy and diagnostic purposes. Contemporary ev...

Apr 9 2026 41966549
Dynamic Surveillance of the Cardiovascular Risk and Identification of Treatment Responders in Type 2 Diabetes Using A Machine Learning-Based Model.

AIMS: To establish a model to predict cardiovascular risk and identify treatment response for patients with type 2 diabetes. METHODS: Data from 11677 ...

Apr 9 2026 41966994
Enhancing Community-Based Nursing Decision Support: Machine Learning Models for Diabetes Risk Prediction Using Home Health Nursing Notes.

OBJECTIVES: This study aimed to identify high-risk factors for type 2 diabetes and develop a machine learning (ML)-based diabetes prediction model usi...

Apr 9 2026 41957825
Objective prediction of siesta based on machine learning and association with obesity.

OBJECTIVES: To predict siesta behavior using machine learning models trained on self-reported and objective data-temperature (T), activity (A), positi...

Apr 9 2026 41963146
Natural Food Pigments: From Biosynthesis to Application.

Natural food pigments primarily originate from two sources: chemical synthesis and plant-derived production. With the rapid advancement of society and...

Apr 9 2026 41954457
Causal mediation analysis with one or multiple mediators: A comparative study.

Mediation analysis decomposes the causal effect of a treatment on an outcome into an indirect effect, mediated through intermediate variables, and a d...

Apr 9 2026 41955059
Innovations in Deaf Health Care Communication: Systematic Review of Sign Language Recognition Systems.

BACKGROUND: Deaf individuals often face communication challenges when interacting with those who can hear. Within health care settings, these challeng...

Apr 9 2026 41955542
Next-generation epidermal patches: Bridging 3D and multidimensional printing for biomedical and personal care innovations.

Advances in additive manufacturing, particularly 3D and multidimensional printing, have enabled unprecedented control over the architecture, compositi...

Apr 8 2026 42005999
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