Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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Beyond Composite Indices: Comprehensive Social Determinants Improve Heart Failure Readmission Prediction.

BACKGROUND: Heart failure (HF) hospitalization readmissions are associated with a high mortality rate and strain the health care system. Both clinical factors and social determinants of health (SDOH) predict HF readmissions, but the optimal approach to incorporating area-level SDOH data remains unclear. METHODS: We merged census tract- and county-level SDOH measures with electronic health record d...

Mar 28 2026 41902736

Comparative Mortality Risk of Aripiprazole, Olanzapine, Quetiapine, and Risperidone in Alzheimer's Disease: A Real‑World Retrospective Cohort Study with Treatment Effect Heterogeneity Analysis.

BACKGROUND: Second-generation antipsychotics (SGAs) are frequently used off-label to manage behavioral symptoms in Alzheimer's disease (AD), despite ongoing concerns about their safety. Comparative evidence on mortality risk across specific SGAs remains limited. In this study, we aim to compare all-cause mortality among patients with AD treated with one of the commonly prescribed SGAs and to explo...

Mar 28 2026 41903051
A Randomised Study of ChatGPT-4o vs. Written Materials for Teaching Periodontal-Systemic Relationships in Dental Education.

INTRODUCTION: The bidirectional relationship between periodontal and systemic diseases (particularly diabetes and cardiovascular diseases) is central ...

Mar 28 2026 41904115
A systematic review of the use of artificial intelligence in mental health-based diabetes care: Current applications and future directions.

AIMS: To map and systematise existing research on the use of artificial intelligence (AI) in mental health-based diabetes care contexts, identify tren...

Mar 28 2026 41904510
Diffusion-Model-Driven Discovery of Ferroelectrics for Photocurrent Applications.

Ferroelectric materials are vital for next-generation memory and photovoltaic technologies, yet their discovery is limited to a few known prototypes. ...

Mar 28 2026 41902482
Most digital psychological interventions for chronic pain fail to measure all 4 dimensions of the quadruple aim of value-based health care: a scoping review.

Psychological treatments are increasingly being developed and delivered using platforms such as mobile applications, online modules, virtual reality, ...

Mar 27 2026 41910406
The transformative role of artificial intelligence in gestational diabetes mellitus: advancements in screening, management, and long-term outcome prediction.

PURPOSE: Artificial intelligence (AI) has emerged as a pivotal tool in enhancing the management of gestational diabetes mellitus (GDM). With its risin...

Mar 27 2026 41908330
Maintenance factors for eating disorder symptoms based on ecological momentary assessment studies: A systematic review.

Several prominent theories of eating disorders maintenance exist, with most corresponding to evidence-based treatments. Ecological momentary assessmen...

Mar 27 2026 41921411
Machine Learning Models to Evaluate County-Level Incidence of Diagnosed Diabetes and Sociodemographic Factors.

AIMS: To evaluate county-level incidence of diagnosed diabetes and key sociodemographic factors in a high-dimensional, nonlinear setting. METHODS: Thi...

Mar 27 2026 42094091
Personalized mapping of body homeostasis using whole-body PET connectomics and routine FDG PET imaging.

BACKGROUND: Immuno-inflammation and systemic alterations are key features of chronic diseases. While PET molecular imaging is widely used in precision...

Mar 27 2026 41896637
Artificial Intelligence for Colorectal Surgeons - Part I: Foundations, Clinical and Educational Applications.

BACKGROUND: Artificial intelligence (AI) is rapidly transforming colorectal surgery through applications spanning screening to postoperative care. Thi...

Mar 27 2026 41891368
Reappraising cardiac function with myocardial contraction fraction: normal values, disease detection, and prognostication.

AIMS: Assessing cardiac function is critical for managing cardiovascular disease, guiding treatment, monitoring progression, and risk stratification. ...

Mar 27 2026 41570115
Exploring the association between Frailty Index and Knee osteoarthritis in middle-aged and older Chinese adults: A cross-sectional analysis of data from the China Health and Retirement Longitudinal Study.

OBJECTIVE: To explore the relationship between Frailty Index (FI) and Knee osteoarthritis (KOA) in Chinese people aged 45 and above. METHODS: Data on ...

Mar 27 2026 41894355
Diagnostic accuracy of AI-assisted chest radiographs in tuberculosis screening: A Ghanaian clinical study.

BACKGROUND: Tuberculosis remains a major global health challenge, particularly in resource-limited settings where access to expert radiological interp...

Mar 27 2026 41894399
An ultrasensitive electrochemical immunosensor for SLC2A3 detection enables prognostic prediction in acute ischemic stroke.

Acute ischemic stroke (AIS) presents significant challenges in biomarker discovery and detection. This study addresses these hurdles through an integr...

Mar 26 2026 41997673
Screening for Alzheimer's disease in the community using an AI-driven screening platform: design of the PREDICTOM study.

BACKGROUND: Recent developments in physiological, imaging and digital biomarkers combined with the approval of new disease-modifying drugs against Alz...

Mar 26 2026 41894949
Multi-dimensional CT feature screening, construction, and validation of a clinical diagnostic model for thyroid eye disease.

OBJECTIVE: Thyroid eye disease (TED) is an autoimmune condition associated with thyroid dysfunction, often presenting with complex and variable orbita...

Mar 26 2026 41895192
Addressing disparities in transthyretin amyloid cardiomyopathy: A systematic review of artificial intelligence in the early identification to improve patient outcomes.

BACKGROUND: Transthyretin amyloid cardiomyopathy (ATTR-CM) remains substantially underdiagnosed among Black patient populations. When applied to non-i...

Mar 26 2026 41896047
Artificial Intelligence in Cardiovascular Medicine: Focus on Hypertension.

Hypertension remains the most prevalent modifiable risk factor for cardiovascular morbidity and mortality worldwide, yet rates of effective blood pres...

Mar 26 2026 41884885
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