Primary Care

Latest AI and machine learning research in primary care for healthcare professionals.

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The economic imperative of artificial intelligence in maternal and neonatal health: a review of evaluation benefits, frameworks, challenges, future perspectives, and limitations.

Integrating artificial intelligence (AI) into maternal and neonatal health (MNH) offers significant opportunities for enhancing patient care through advanced predictive modeling, early disease diagnosis, and ongoing monitoring of conditions such as preeclampsia or gestational diabetes. However, significant challenges in economic valuation persist, including data scarcity, complexity, and the nasce...

Mar 14 2026 41832507

Routine blood tests and machine learning identify complications in high myopia.

High myopia can lead to cataract, glaucoma, retinal detachment, choroidal neovascularisation, and macular degeneration, causing irreversible vision loss. Imaging detects these complications, but population screening is limited by equipment, and specialist availability. Here we show that a machine learning model using routine blood test results identifies people at increased risk of complications r...

Mar 14 2026 41826348
Chronological Diagnostic Algorithm Predicting Neuropathology in Parkinsonism.

OBJECTIVE: Pre-mortem diagnosis of parkinsonism is often challenging due to atypical presentations, overlapping syndromes, and co-pathologies. This st...

Mar 14 2026 41830446
A review of artificial intelligence-based research on chronic obstructive pulmonary disease.

In recent years, with the rapid development of artificial intelligence (AI), Chronic Obstructive Pulmonary Disease (COPD), one of the world's three ma...

Mar 14 2026 41839412
Unsupervised identification of muscle phenotypes in adults with obesity: a data-driven framework for the identification of sarcopenia in absence of a gold standard.

BACKGROUND: Sarcopenia is characterized by progressive loss of skeletal muscle mass and strength and is associated with increased disability and morta...

Mar 13 2026 41846055
Nanozymes: The Emerging Frontier in Catalytic Nanomaterials and Their Therapeutic Applications.

Artificial nanomaterials known as nanozymes, which possess inherent enzyme-mimetic characteristics, have transformed environmental research, biomedici...

Mar 13 2026 41832626
Federated clinical concept and disease semantic learning for congenital heart disease diagnosis.

Effective first-trimester screening for congenital heart disease (CHD) remains an unmet clinical need, hindered by technical constraints and the lack ...

Mar 13 2026 41826415
Clustering of cardiovascular risk factors and their association with socio-demographic and lifestyle factors in middle-aged and older adults in rural northeast South Africa: Findings from HAALSI.

OBJECTIVES: This study examined patterns of clustering of intermediate risk factors for Cardiovascular diseases (CVDs) in a rural South African popula...

Mar 13 2026 41830695
Interpretable Graph Convolutional Networks for cardiovascular disease risk prediction in patients with Type 2 Diabetes Mellitus.

BACKGROUND: Cardiovascular disease (CVD) is the most prevalent complication of Type 2 Diabetes Mellitus (T2DM) and a leading cause of mortality in thi...

Mar 13 2026 41830753
Machine Learning Models for Identifying Dental Pain in Adolescents.

INTRODUCTION: This study aimed to identify dental pain using machine learning (ML) algorithms in Brazilian adolescents for public health screening pur...

Mar 13 2026 41830787
Development and Validation of a Deep Learning System for Echocardiographic Assessment of 16-Segment LV Wall Thickness.

OBJECTIVES: The quantitative analysis of 16-segment left ventricular wall thickness can provide insights into the pathological progression of left ven...

Mar 13 2026 41832107
Evaluating the performance of a custom GPT in full text screening of a systematic review.

AIM: Systematic reviewing is a time-consuming process that can be aided by artificial intelligence (AI). There are several AI options to assist with t...

Mar 13 2026 41823326
Machine learning diagnostic framework for liver fibrosis in chronic hepatitis B based on routine laboratory tests.

Early detection of liver fibrosis in chronic hepatitis B (CHB) patients is crucial for improving their prognosis. This study aims to develop a machine...

Mar 13 2026 41824881
Causal Discovery in Observational Medical Research: Scoping Review.

BACKGROUND: Observational data are fundamental to medical research but present formidable challenges for causal inference. Machine learning-based caus...

Mar 13 2026 41824946
Artificial Intelligence Interventions Targeting Obesity-Related Behaviors: Protocol for a Scoping Review.

The objective of this scoping review is to examine the nature, extent, and impact of AI-supported interventions that include an AI agent intended to i...

Mar 13 2026 41825969
Breast density reporting in Aotearoa New Zealand: policy imperatives and research priorities.

Breast density influences both breast cancer risk and the sensitivity of mammographic screening. Several countries routinely notify women of their bre...

Mar 13 2026 41818763
A complete blood count-based machine learning model for rapid differentiation of aplastic anemia, immune thrombocytopenia, and myelodysplastic syndromes in routine clinical practice.

BACKGROUND: Accurate differentiation of common hematologic disorders remains challenging in routine clinical practice and often requires invasive diag...

Mar 12 2026 41867472
Systematic review of Artificial Intelligence-based methods for glycemic control and risk prediction in intensive care units.

BACKGROUND: Achieving safe glycemic targets in intensive care remains difficult due to rapidly changing physiology, treatment effects, and measurement...

Mar 12 2026 41844000
Immune-activated & pathology-characterized: the distinct clear cell renal cell carcinoma subtypes for 3PM strategies derived from artificial intelligence in multi-omics.

BACKGROUND AND OBJECTIVE: Renal clear cell carcinoma (ccRCC) is highly heterogeneous, with significant differences in clinical outcomes such as progno...

Mar 12 2026 42179463
Advancements in Screening Strategies for Early-Onset Colorectal Cancer (EOCRC).

Screening for early-onset colorectal cancer is a growing public health concern, driven by a rising incidence in younger adults. As trends shift, scree...

Mar 12 2026 42020075
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