Psoriasis

From intuition to optimization: a review of inverse design applied to optical nanotweezers.

Optical nanotweezers, which integrate nanophotonic structures such as plasmonic antennas, dielectric resonators, and metasurfaces, have emerged as powerful tools for manipulating nanoparticles, biomolecules, and viruses with high precision. However, traditional designs rely heavily on heuristic approaches and simple geometries, limiting performance. Inverse design offers a paradigm shift by using ...

Design of three-mode free-form nanostructured optical fibers: comparison of dense and convolutional neural networks in Generative Inverse Design Networks approach.

We report a numerical study on the inverse design of the internal structure of weakly coupled three-mode fibers. We explored a new class of optical fibers - free-form nanostructured fibers (FFNFs) - operating at 1550 nm for potential application in Mode-Division Multiplexing (MDM) systems. The fiber geometries were generated and optimized within the Generative Inverse Design Networks (GIDNs) frame...

Prognostic prediction models for psoriatic arthritis in psoriasis: A systematic review.

BACKGROUND: Psoriatic arthritis is a chronic inflammatory arthropathy that affects up to 22% of individuals with psoriasis. Identifying patients at hi...

Integrated bioinformatics and machine learning for shared diagnostic genes and mechanisms between periodontitis and psoriasis.

BACKGROUND: Periodontitis and psoriasis are two prevalent conditions that are bidirectionally associated. However, the molecular basis remains poorly ...

From trial-and-error to inverse design: how AI is redefining drug delivery systems.

AI is transforming drug delivery system (DDS) design by enabling predictive modeling and inverse design strategies. Recent advances integrating machin...

Causal multi-fidelity surrogate forward and inverse models for ICF implosions.

Continued progress in inertial confinement fusion (ICF) requires solving inverse problems relating experimental observations to simulation input param...

Gold-Functionalized Multilayer Heterojunction Microarchitectures Enable High-Fidelity Serum Metabolite Profiling for Skin Cancer Subtype Classification.

Skin cancer is among the most prevalent malignancies worldwide, with non-melanoma types ranking among the top five and melanoma characterized by high ...

Reconstructing the Hamiltonian from the local density of states using neural networks.

Reconstructing a quantum system's Hamiltonian from limited yet experimentally observable information is interesting both as a practical task and from ...

Machine-learning-guided inverse design of lead-free relaxors enabled by multimodal literature mining.

Lead-free relaxors combining high permittivity with thermal robustness are essential for integrated electronics and power systems operating at elevate...

New Frontiers of Skin Ultrasound in Precision Medicine.

Ultrasound has emerged as a versatile, non-invasive imaging technique in dermatology, offering real-time, high-resolution visualization of cutaneous s...

Mathematic and Computational Models for Osseointegration in Titanium Dental Implants: A Systematic Review of Current Approaches and Future Directions.

PURPOSE: To identify, compare, and critically evaluate the main mathematic and computational models used to study osseointegration in titanium (Ti) de...

Evaluating the quality of artificial intelligence responses to psoriasis-related clinical and patient questions: a comparative study of ChatGPT, Gemini, and Microsoft Copilot.

BACKGROUND: Patient use of artificial intelligence (AI) chatbots for dermatologic information is increasing, but their performance on psoriasis-relate...

Enhanced Diagnosis of Generalized Pustular Psoriasis With the Legit.Health Device as a Diagnosis Support Tool: Multireader Multicase Study.

BACKGROUND: Generalized pustular psoriasis (GPP) is a rare, chronic, systemic inflammatory disease with an unpredictable and heterogeneous clinical co...

Informatics-Based Psychotherapeutic and Psychiatric Interventions in Dermatology: Scoping Review of Impacts on Skin Disease Severity and Mental Health Outcomes.

BACKGROUND: Chronic dermatologic conditions such as psoriasis, atopic dermatitis, and hidradenitis suppurativa are associated with a high burden of ps...

Inverse Analysis of Near-edge Spectra: Toward the Prediction of Chemical Bonding and Atomic Structure.

Near-edge structure of core-loss spectra, including electron energy-loss near-edge structure (ELNES) measured by transmission electron microscopy and ...

Development and External Validation of a Transcriptome-Based Multivariable Prediction Model for Treatment-Free Remission in Chronic Myeloid Leukemia.

PURPOSE: Treatment-free remission (TFR) is a major therapeutic objective in chronic myeloid leukemia (CML). However, nearly 50% of patients relapse af...

Inverse Design of Amorphous Materials With Targeted Properties.

Disordered (amorphous) materials, such as glasses, are emerging as promising candidates for applications within energy storage, nonlinear optics, and ...

A Large-Scale Nanocrystal Database with Aligned Synthesis and Properties, Enabling Generative Inverse Design.

Nanocrystal synthesis has been highly dependent on trial and error due to the complex correlation between synthesis parameters and physicochemical pro...

Neural Network Enabled Real-Time Plasma Imaging for Inverse Designed Fabrication of Micro/Nano Structures with Ultrafast Laser.

Real-time monitoring is essential for quality control in highprecision micro/nano structure fabrication with ultrafast laser. The laser-induced plasma...

Deep Learning Inverse Design of Phase-Change Reconfigurable Terahertz Metadevices for Multidimensional Secure Communication.

The exponential rise in data exchange and cyber threats in next-generation 6G networks demands communication systems that are inherently secure at the...