Psychiatry

Latest AI and machine learning research in psychiatry for healthcare professionals.

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An fMRI dataset of verbalized spontaneous thought with annotated transcripts and self-report trait measures

Spontaneous thought is pervasive in everyday human cognition, yet datasets capturing its neural dynamics under minimally interrupted conditions remain limited. The current dataset was acquired from a think-aloud functional MRI experiment in which 118 participants continuously verbalized their spontaneous thoughts during 10-minute scanning sessions. The raw MRI data and verbal transcripts with sent...

Artificial intelligence for detecting bipolar disorder in electronic health records of patients with affective diagnoses: a diagnostic accuracy study

Background: Bipolar disorder (BD) is frequently underdiagnosed, particularly in patients presenting with depressive disorders, leading to delays in appropriate treatment. Artificial intelligence (AI) applied to electronic health records (EHRs) may improve early detection by identifying clinically relevant symptom patterns. Objective: To evaluate the diagnostic performance of a natural language pro...

The Relatives Experience Questionnaire for Acute Inpatient Child and Adolescence Mental Health Services (REQ-AICAMHS): reliability and validity following a Norwegian survey

Introduction: Adolescents with mental health disorders represent a vulnerable group with complex care needs, yet their and their relatives experiences...

Conserved neuroectodermal aging encodes primate health and longevity

Neuroectoderm-derived tissues are highly metabolically active and exhibit minimal regenerative turnover, rendering them uniquely vulnerable to age-rel...

Mixed-Precision Information Bottlenecks for On-Device Trait-State Disentanglement in Bipolar Agitation Detection

Continuous monitoring of bipolar disorder agitation via voice biomarkers requires disentangling stable speaker traits from volatile affective states o...

May 4 2026 2605.03039v1
Predicting first-onset depression in adolescents: Do general population models generalize to youth with ADHD?

Background: Most studies seeking to identify youth at increased risk for depression have developed prediction models using a limited set of risk facto...

Forecasting Minute-by-Minute Stress, Anxiety, and Affective States Using Time-Series Analysis of Wearable Sensor Data

This paper focuses on forecasting minute-by-minute stress, anxiety, and affective states using wearable sensor data. It addresses mental health as a g...

Artificial Intelligence Agents in Mental Health: A Systematic Review and Meta Analysis

The rapid rise of large language models (LLMs) and foundation models has accelerated efforts to build artificial intelligence (AI) agents for mental h...

Residual Gaussian Splatting for Ultra Sparse-View CBCT Reconstruction

While 3D Gaussian splatting (3DGS) offers explicit and efficient scene representations for cone-beam computed tomography reconstruction, conventional ...

Apr 30 2026 2604.27552v1
Entropy-Dominated Temporal Vocal Dynamics as Digital Biomarkers for Depression Detection

Automated depression detection often relies on static aggregation of conversational signals, potentially obscuring clinically meaningful behavioral dy...

Apr 29 2026 2604.26998v1
Fidelity, Diversity, and Privacy: A Multi-Dimensional LLM Evaluation for Clinical Data Augmentation

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learnin...

Apr 29 2026 2604.27014v1
An Interpretable Deep Learning Framework Reveals Frontoparietal Control Network Hyperactivation Underlying Autism Diagnosis and Symptom Severity

BACKGROUND: Autism spectrum disorder (ASD) is marked by profound neurobiological heterogeneity, which drives inconsistent neuroimaging findings and im...

Adolescent Astrocyte Dysregulation Impairs Prefrontal Interneuron Maturation and Adult Cognition

The prefrontal cortex (PFC), a brain region critical for executive and cognitive functions, is characterized by its protracted maturation extending th...

BETA: Resting-state fMRI Biotypes for tDCS Efficacy in Anxiety Among Older Adults At Risk For Alzheimer's Disease

Anxiety is usually gauged by self-report, yet a single symptom level can reflect disparate neural circuitry. In Alzheimer's disease and related dement...

Toward trustworthy clinical AI for obsessive-compulsive disorder: reliability, generalizability, and interpretability of a transformer model across the ENIGMA-OCD consortium

Background. Studies applying machine learning to obsessive-compulsive disorder (OCD) typically report accuracy in homogeneous samples but rarely asses...

Psychologically-Grounded Graph Modeling for Interpretable Depression Detection

Automatic depression detection from conversational interactions holds significant promise for scalable screening but remains hindered by severe data s...

Apr 27 2026 2604.24126v1
Uncovering Latent Patterns in Social Media Usage and Mental Health: A Clustering-Based Approach Using Unsupervised Machine Learning

The widespread adoption of social media has heightened interest in its psychological effects, particularly on mental health indicators such as anxiety...

Apr 27 2026 2604.24611v1
FAIR_XAI: Improving Multimodal Foundation Model Fairness via Explainability for Wellbeing Assessment

In recent years, the integration of multimodal machine learning in wellbeing assessment has offered transformative potential for monitoring mental hea...

Apr 26 2026 2604.23786v1
Reliable Self-Harm Risk Screening via Adaptive Multi-Agent LLM Systems

Emerging AI systems in behavioral health and psychiatry use multi-step or multi-agent LLM pipelines for tasks like assessing self-harm risk and screen...

Apr 24 2026 2604.22154v1
Foundation models for discovering robust biomarkers of neurological disorders from dynamic functional connectivity

Several brain foundation models (FM) have recently been proposed to predict brain disorders by modelling dynamic functional connectivity (FC). While t...

Apr 23 2026 2604.22018v1
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