Latest AI and machine learning research in psychiatry for healthcare professionals.
The mammalian prefrontal cortex encodes variables related to goal-directed behavior, and enables flexibility during environmental changes, making it critical to understand how the dynamic updating vs. stable maintenance of different encodings contribute to behavioral adaptation. We addressed this by comparing prefrontal encoding during successful adaptation vs. maladaptive perseveration. Specifica...
Fibromyalgia (FM) involves widespread musculoskeletal pain and hypersensitivity, often accompanied by neurological, cognitive, and affective disturbances. Resting-state (RS) electroencephalography (EEG) studies have revealed abnormal brain activity in chronic pain conditions, with anxiety and symptom duration potentially exacerbating these alterations. This study applied multivariate pattern analy...
Novelty is a double-edged sword for agents and animals alike: they might benefit from untapped resources or face unexpected costs or dangers such as p...
Reactivation in sleep alters the structure of memories and can potentially be used to restructure upsetting representations. Reactivation can be trigg...
Depression is neurobiologically and clinically heterogeneous. New approaches using resting-state functional MRI (rs-fMRI) functional connectivity (FC)...
Social camouflaging refers to strategies to hide or compensate for social difficulties, often at a significant mental health cost, and is particularly...
Motivation drives individuals to overcome costs to achieve desired outcomes, such as rewards or avoidance of punishment, with significant variability ...
The olfactory bulb (OB), the first central relay of the olfactory pathway, plays a critical role in odor perception and exhibits remarkable structural...
Mesocorticolimbic dopamine projections are crucial for value learning, motivational control, and cognitive functions, but their precise neurocomputati...
Humans frequently make decisions that impact close others. Prior research has shown that people have stable preferences regarding such decisions and m...
Bipolar disorder (BD) is characterized by fluctuating mood states, yet the cellular and circuit-level mechanisms distinguishing lithium-responsive (LR...
Predictive processing theories propose that the brain supervises itself, to build an internal model of its environment. This internal model emerges by...
Differential graph inference is a critical analytical technique that enables researchers to accurately identify the variables and their interactions t...
Recurrent neural networks with balanced excitation and inhibition exhibit irregular asynchronous dynamics, which is fundamental for cortical computati...
The cannabinoid type-1 receptor (CB1R) signaling pathway plays a central role in regulating motivational and feeding behaviors. Neutral CB1R antagonis...
Pavlovian “approach or avoid” impulses are critical behavioral biases that, in excess, are linked to multiple psychiatric conditions. To investigate h...
Altered stress responses are closely linked to mental disorders, but the role of brain structure in acute cortisol responses to psychosocial stress re...
Studies of human sociability indicate stronger social affinity in matched-neurotype dyads (e.g., two individuals with autism or two without) compared ...
The human claustrum is a bilateral, thin, irregularly shaped gray matter structure located between the striatum and insula. While previous research de...
In eukaryotes, most genes produce multiple transcript isoforms that diversify the transcriptome and proteome, serving as a key mechanism of functional...