Psychiatry

Latest AI and machine learning research in psychiatry for healthcare professionals.

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Deep learning for depression prediction in older adults: A retrospective cohort study from CHARLS (2011-2020) with independent cohort validation in CLHLS (2008-2018).

BACKGROUND: Geriatric depression is highly prevalent yet under-recognized, severely affecting older adults' quality of life and social functioning. There is an urgent need for individualized early prediction tools. While deep learning (DL) holds potential, its systematic application in this domain remains underdeveloped. METHODS: Utilizing five waves (2011-2020) of the China Health and Retirement ...

Jan 17 2026 41554486

Dual-representation structural MRI classification of psychiatric disorders using deep learning and large language models.

Accurate differentiation among psychiatric disorders such as schizophrenia and bipolar disorder remains a significant clinical challenge due to overlapping symptoms and subtle neuroanatomical variations. This study proposes a dual-representation structural MRI framework in which raw T1-weighted MRI slices and their corresponding color-coded tissue segmentation maps-both derived from the same imagi...

Jan 16 2026 41576904
Exploring Primary and Interaction Effects of Minor Physical Anomalies: Development and Validation of Prediction Models Using Explainable Machine Learning Algorithms for Early-Onset Schizophrenia.

BACKGROUND AND HYPOTHESIS: Minor physical abnormalities (MPAs) are neurodevelopmental markers that can be traced to prenatal events and may be signifi...

Jan 16 2026 40178447
The Retinal Age Gap as a Marker of Accelerated Aging in the Early Course of Schizophrenia.

BACKGROUND AND HYPOTHESIS: Given the available findings confirming accelerated brain aging in schizophrenia (SZ), we conducted a study aimed at verify...

Jan 16 2026 40227154
Mental Health Professionals' Perspectives on Digital Remote Monitoring in Services for People with Psychosis.

BACKGROUND AND HYPOTHESIS: Digital remote monitoring (DRM) captures service users' health-related data remotely using devices such as smartphones and ...

Jan 16 2026 40329411
Attitudes of psychiatric nurses towards the integration of artificial intelligence applications to clinical care: a qualitative study in China.

BACKGROUND: The application of artificial intelligence in mental health faces unique challenges. Psychiatric nurses provide direct care to patients wi...

Jan 16 2026 41540475
Opportunities and Challenges in Precision Neurotherapeutics.

Precision neurotherapeutics represents a transformative paradigm shift from standardized "one-size-fits-all" treatments of neurological, neurodegenera...

Jan 16 2026 41543941
Data Science Education for Residents, Researchers, and Students in Psychiatry and Psychology: Program Development and Evaluation Study.

BACKGROUND: The use of artificial intelligence (AI) to analyze health care data has become common in behavioral health sciences. However, the lack of ...

Jan 16 2026 41544003
Development and external validation of machine learning approaches for risk prediction of cardiovascular disease in individuals with schizophrenia: a nationwide Swedish and Danish study.

BACKGROUND: Currently available cardiovascular disease (CVD) risk prediction tools may underestimate the risk in individuals with schizophrenia. OBJEC...

Jan 16 2026 41545227
Deep learning for detecting depression in individuals with and without alexithymia.

BACKGROUND: To accurately detect individuals' mental health issues using artificial intelligence and self-report scales, it is crucial to recognize ho...

Jan 16 2026 41545479
Machine learning guided structural dynamics identifies translation elongation factor 1 (EEF1A1) as an immunological biomarker and marine natural products as therapeutic leads for rheumatoid arthritis with major depressive disorder.

Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects synovial joints, especially those of the hands, elbows, wrists, ...

Jan 16 2026 41547049
Variant-resolved prediction of context-specific isoform variation with a graph-based attention model.

In eukaryotes, most genes produce multiple transcript isoforms that diversify the transcriptome and proteome, serving as a key mechanism of functional...

Jan 16 2026 41547351
Integrating Artificial Intelligence Into Exposure Therapy: A One Year Follow-Up Case Report of Emetophobia With Comorbid Panic Disorder.

Emetophobia is a specific phobia characterized by an intense fear of vomiting, often accompanied by panic attacks, hypervigilance to bodily sensations...

Jan 16 2026 41550407
Healthcare utilization and chronic condition clusters in multimorbidity patients using weighted k-means: a register-based study in Denmark.

BACKGROUND: The growing burden of multimorbidity challenges the healthcare system due to increased healthcare utilization and uncoordinated care. Iden...

Jan 15 2026 41551862
Biometric Data in Post-Traumatic Stress Disorder Detection: A Scoping Review of Digital Health Applications.

CONTEXT: Post-traumatic stress disorder (PTSD) is mainly assessed through self-reports and clinician interviews, which can delay recognition and limit...

Jan 15 2026 41633287
Exploration of Mental Health and Stress Among Nursing Interns Through a Chatbot: A Single-Group Pilot Study.

BACKGROUND: Nursing interns face early clinical distress; chatbot-based mental health tools show promise, although evidence of their feasibility and e...

Jan 15 2026 41533862
Transforming mental health research and care through artificial intelligence.

Artificial intelligence (AI) holds transformative potential for the care of people with mental health illnesses. This Review explores key domains and ...

Jan 15 2026 41538442
Increasing engagement with cognitive-behavioral therapy (CBT) using generative AI: a randomized controlled trial (RCT).

BACKGROUND: Shortages in mental healthcare lead to long periods of inadequate support for many patients. While digital interventions offer a scalable ...

Jan 15 2026 41540194
How Should We Prompt Engineer Our Health Coach Bots? Stoicism, Epicureanism or Something Else?

Healthcare is among the fastest growing sectors utilizing artificial intelligence to improve efficiency, quality and accessibility to services. In par...

Jan 15 2026 41540727
Digital biomarkers for brain health: passive and continuous assessment from wearable sensors.

Continuous and scalable monitoring of cognition and affective states is critical for the early detection of brain health, which is currently limited b...

Jan 14 2026 41530307
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