Public Health & Policy

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events.

Bioactive compounds derived from natural products (NPs) continue to attract considerable scientific interest due to their wide range of beneficial biological activities. This review examines the role of these compounds in the prevention and management of cardiovascular disease (CVD), with particular emphasis on their involvement in thrombotic processes. Specifically, this review addresses whether ...

Digital Conversation Companions.

Advances in voice recognition and artificial intelligence (AI) could soon yield digital conversation companions-software that combines conversational AI with health monitoring and promotion. We describe how this technology, once developed and deployed, could transform the way older adults age and receive care. By obviating the need to read or type, the software could be used by individuals with re...

Evaluation of a Digital Intervention for Monitoring and Improving Medication Adherence Among Real-World e-Consumers of HIV Preexposure Prophylaxis in China: Protocol for a Randomized Controlled Trial.

BACKGROUND: Preexposure prophylaxis (PrEP) is a key biomedical HIV prevention strategy that relies heavily on adherence for optimal effectiveness. In ...

Echocardiographic assessment in arterial hypertension: a contemporary narrative review.

Arterial hypertension remains the leading modifiable cause of cardiovascular morbidity and mortality resulting in characteristic changes in cardiac st...

Automated iridocorneal angle classification using a multimodal large language model.

PURPOSE: To evaluate the diagnostic performance of a general-purpose vision-language model (GPT-4o) in interpreting gonioscopic images of the anterior...

Combined Effects and Potential Mechanisms of Multiple Metals Exposure on Coronary Artery Disease in the US Population: An Integrated Epidemiological and Network Toxicology Study.

Coronary artery disease (CAD) emerged as a major global health burden, but the relationship between multiple metals exposure and CAD and its toxicolog...

TACE-induced liver injury in hepatocellular carcinoma: mechanisms, prediction, and prevention in the era of gut microbiota and inflammasome research.

Transarterial chemoembolization (TACE) is a cornerstone locoregional therapy for hepatocellular carcinoma (HCC), yet most candidates also have cirrhos...

CIST: A clade-informed sequence transformer framework for predicting influenza virus antigenicity.

Rapid antigenic evolution of influenza viruses complicates timely vaccine strain selection and renders prospective interpretation of serological assay...

Spatiotemporal genomic analysis and risk assessment of the plasmids carrying blaOXA-48-like genes based on a large-scale international dataset.

BACKGROUND: The spread of OXA-48-like carbapenemases represents a major public health challenge. Although previous studies have investigated OXA-48-li...

Exploratory 6-year prediction of LTCI certification using KCL data: A decision tree analysis in a retrospective observational study.

Amid the progression of an aging society, it is essential to develop a long-term predictive model capable of distinguishing between older adults with ...

Augmenting Pediatric Care With Artificial Intelligence: Opportunities and Responsibilities for Nurse Practitioners.

BACKGROUND: Artificial intelligence (AI) is emerging as a critical tool for nurse practitioners delivering pediatric and adolescent and young adult (A...

Automated Identification of Surgical Site Infections From Electronic Medical Records: Retrospective Observational Predictive Modeling Study.

BACKGROUND: Surgical site infections (SSIs) affect 160,000 to 300,000 patients annually, increasing postoperative mortality, causing significant compl...

Neural networks and behavioral frameworks to analyse the impact of media and individual awareness for controlling epidemics.

Enhancing individual awareness and immunization are generally recognized as fundamental strategies for controlling infectious diseases. Awareness is i...

Artificial intelligence-based prediction of diseases among homeless populations in Bogotá: Implications for targeted interventions.

BACKGROUND: The homeless population in Bogotá exhibits complex social and health vulnerabilities, with a high prevalence of chronic and communicable d...

Application value and challenges associated with plasma cell-free DNA metagenomic sequencing technology in the diagnosis of infections in patients with hematological disorders.

In patients with hematological disorders, the high risk of complex infections caused by immune dysfunction and intensive therapies poses a major chall...

Review Article: Advances in the Diagnosis of Dysplasia in Barrett's Oesophagus.

BACKGROUND: Barrett's oesophagus (BE), the precursor to oesophageal adenocarcinoma, progresses through a stepwise dysplastic sequence. Accurate dyspla...

The evolving landscape of acute kidney injury: research directions and changes in clinical practice.

Acute kidney injury (AKI) is a common and serious disease, needing a comprehensive and management-based approach. While traditional practice focused o...

Translational applications of artificial intelligence and machine learning for mosquito-borne disease control in low- and middle-income countries.

OBJECTIVES: To synthesize evidence on the application of artificial intelligence (AI) and machine learning (ML) for mosquito-borne disease (MBD) contr...

Protocols for genomic epidemiology and source attribution of enteric bacteria causing diarrhoeal disease across Africa.

INTRODUCTION: Enteric bacterial pathogens are a major cause of diarrhoeal disease in low-income and middle-income countries, with complex transmission...

A bibliometric analysis of research trends and future directions in early detection of pancreatic cancer.

BACKGROUND: Research on the early detection of pancreatic cancer has grown rapidly in recent years; however, existing bibliometric studies in this fie...