Pulmonology

Artificial Intelligence Assisted 18F-FDG PET Radiomics in Classifying Histological Subtypes of Lung Cancer: Systematic Review and Meta-analysis.

UNLABELLED: AI-assisted radiomics is an emerging tool for precision oncology, and many studies have recently shown promising results. However, there are still differences in whether it can be applied in clinical practice. This study aimed to evaluate the diagnostic accuracy of PET-based radiomics in ML models for histological subtype classification of lung cancer through a systematic review and me...

Discrimination of Respiratory Tract Infections by a Reduced Graphene Oxide Array Modified with Metal-Organic Frameworks and Metal Phthalocyanines.

As a prevalent clinical condition, it is critical to distinguish between bacterial and viral respiratory tract infections given their pivotal role in guiding appropriate pharmaceutical interventions and preventing antibiotic misuse. Exhaled breath (EB) contains a spectrum of disease-specific biomarkers, enabling precise diagnostic analysis. Thus, EB analysis using an electronic nose (e-nose) to re...

A Novel Approach to Sequential Organ Failure Assessment (SOFA) Using Near-Infrared Spectroscopy in Extracorporeal Membrane Oxygenation (ECMO) Patients.

Extracorporeal membrane oxygenation (ECMO) is a medical device that provides temporary external circulation and respiratory support during heart-lung ...

Multimodal Analysis of Factors Associated with Respiratory Symptoms in Colombian Informal Waste Pickers: A Study Based on Statistical Models and Machine Learning Algorithm.

This study aimed to assess the prevalence of respiratory symptoms among informal waste pickers in Colombia and identify the contributing demographic, ...

Impact of sarcopenia and obesity on mortality in older adults with SARS-CoV-2 infection: automated deep learning body composition analysis in the NAPKON-SUEP cohort.

INTRODUCTION: Severe respiratory infections pose a major challenge in clinical practice, especially in older adults. Body composition analysis could p...

Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the predominant subtype of renal cancer, with a poor prognosis driven by therapy resistance and...

A plasma 9-microRNA signature for lung cancer early detection: a multicenter analysis.

Lung cancer remains the leading cause of cancer-related deaths worldwide. Low-dose computed tomography (LD-CT) screening, combined with effective mini...

Application of Quantitative CT and Machine Learning in the Evaluation and Diagnosis of Polymyositis/Dermatomyositis-Associated Interstitial Lung Disease.

RATIONALE AND OBJECTIVES: To investigate lung changes in patients with polymyositis/dermatomyositis-associated interstitial lung disease (PM/DM-ILD) u...

Technology advances in the placement of naso-enteral tubes and in the management of enteral feeding in critically ill patients: A narrative study.

Enteral feeding needs secure access to the upper gastrointestinal tract, an evaluation of the gastric function to detect gastrointestinal intolerance,...

Breath Insights: Advancing Lung Cancer Early-Stage Detection Through AI Algorithms in Non-Invasive VOC Profiling Trials.

Lung cancer (LC) is the leading cause of cancer-related deaths worldwide. Effective screening strategies for early diagnosis that could improve disea...

AI-Enabled Diagnostic Prediction within Electronic Health Records to Enhance Biosurveillance and Early Outbreak Detection.

Detecting infectious disease outbreaks promptly is crucial for effective public health responses, minimizing transmission, and enabling critical inter...

Emerging research themes in ferroptosis research for non-small cell lung cancer: a bibliometric and visualized analysis.

BACKGROUND: Ferroptosis, an iron-dependent form of regulated cell death, has garnered significant attention as a potential therapeutic target in oncol...

Predicting infections with multidrug-resistant organisms (MDROs) in neurocritical care patients with hospital-acquired pneumonia (HAP): development of a novel multivariate prediction model.

Hospital-acquired pneumonia (HAP) is prevalent in the neuro-intensive care unit (NICU), significantly increasing susceptibility to infections with mul...

Propofol-associated Hypertriglyceridemia: Development and Multicenter Validation of a Machine-Learning-Based Prediction Tool.

To develop and validate an explainable machine learning (ML) tool to help clinicians predict the risk of propofol-associated hypertriglyceridemia in c...

Nucleic acid spheres for treating capillarisation of liver sinusoidal endothelial cells in liver fibrosis.

Liver sinusoidal endothelial cells (LSECs) lose their characteristic fenestrations and become capillarized during the progression of liver fibrosis. M...

ITGAV, a specific biomarker associated with the pathogenesis of idiopathic pulmonary fibrosis.

Objective Idiopathic pulmonary fibrosis (IPF), which radiologically/pathologically manifests mainly as usual interstitial pneumonia (UIP), is easily c...

Minimum clinically important difference in Quantitative Lung Fibrosis score associated with all-cause mortality in idiopathic pulmonary fibrosis: subanalysis from two phase II trials of pamrevlumab.

OBJECTIVES: Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease. Chest high-resolution CT (HRCT) is instrumental in IPF man...

Exosomes derived from human umbilical cord mesenchymal stem cells attenuate senescence of peritoneal mesothelial cells by inhibiting oxidative stress.

OBJECTIVE: Aging is a natural process that affects cellular function. In peritoneal dialysis (PD), chronic exposure to dialysate induces oxidative str...

Jumping on the moon as a potential exercise countermeasure.

The Moon's gravitational field strength (17% Earth's gravity) may facilitate the use of bodyweight jumping as an exercise countermeasure against muscu...

Heat to hypoxia cross-adaptation: Effects of 6-week post-exercise hot-water immersion on exercise performance in acute hypoxia.

Cross-adaptation occurs when exposure to one environmental stressor (e.g., heat) induces protective responses to another (e.g., hypoxia). Although pos...