Pulmonology

Latest AI and machine learning research in pulmonology for healthcare professionals.

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Spatial Graph Representation and Morphometric Analysis of the Pulmonary Vascular Tree From Computed Tomography Using Multi-Scale Hessian-Based Filter Fusion and TEASAR Skeletonization

Reconstructing the pulmonary vascular tree from computed tomography (CT) images is essential for quantitative lung analysis, vascular morphology assessment, and patient-specific modeling, yet it remains challenging because vessels span multiple scales, from proximal arteries to distal microvasculature. Clinical chest CT is further affected by limited spatial resolution, partial volume effects, het...

Jul 5 2026 2607.04457v1

Improving Generalizability in Whole-Cell Antibiotic Discovery Through Active Learning

Machine learning (ML) has accelerated molecular discovery, yet training models to generalize to out-of-distribution (OOD) chemical spaces remains fundamentally constrained by the high cost of experimental validation. In antibiotic discovery, where whole-cell phenotypic high throughput screening (HTS) is resource-intensive, iterative ML-guided compound selection, or Active Learning (AL), offers a p...

Benchmarking the translational potential of AI-based drug-resistance prediction from Mycobacterium tuberculosis whole-genome sequencing data

Background: Tuberculosis, especially drug-resistant tuberculosis (DR-TB) including multidrug-resistant (MDR) and extensively drug-resistant (XDR) stra...

Personalized planning of cardiac resynchronization therapy through integration of coronary sinus geometry, clinical data, digital twins, and machine learning: visualization, stratification, and optimization

Background: Cardiac resynchronization therapy (CRT) fails in 30% of patients, often due to suboptimal left ventricular pacing site (LVPS) selection. C...

X-Splat: Gaussian Splatting for 3D CBCT Generation from Single Panoramic Radiograph

Generating a 3D dental volume from a single panoramic radiograph (PXR) could provide a low-radiation alternative to Cone-Beam Computed Tomography (CBC...

Jul 2 2026 2607.02099v1
Predicting Mechanical Ventilation Requirement in Guillain-Barre Syndrome using a Multi-Functional Machine Learning Algorithm

Background: To develop and validate multiple Machine Learning (ML) algorithms that predict Mechanical Ventilation (MV) requirement in Guillain-Barre S...

DDTRN: Predicting Bacterial Transcriptional Regulatory Networks Based on Gene Sequences using Dual Descriptor

Accurate computational reconstruction of bacterial transcriptional regulatory network (TRN) from sequence information alone remains a fundamental chal...

NLP Framework for Automated Symptom Severity Staging in Heart Failure and COPD Clinical Notes Using Ontology Integration: A Study Protocol

Background: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are among the leading causes of morbidity and mortality globally, with...

Proposed Context-of-Use Evaluation Framework for Medication Management Tasks Completed by Generative Artificial Intelligence

Background: Standardized evaluation of agentic artificial intelligence (AI) for medication management is lacking. Given the potential lethality of med...

A Robust Machine Learning Framework for Keloid Biomarker Discovery Beyond Differential Expression

Keloids are fibroproliferative skin disorders arising following dermal injury that extend beyond the original wound margins. Their pathogenesis remain...

Accurate Recognition of Pneumonia and COVID-19 by Geometric Shape Normalization of Lung Region using Automatic Landmark Detection and Piecewise Affine Warping

This paper presents an automatic system for recognizing pulmonary diseases in chest X-rays using geometric normalization of the lung region. The metho...

Jun 29 2026 2606.29715v1
Physically-Constrained Harmonic Separation for Robust Heart and Respiratory Rate Estimation from Wrist Photoplethysmography

Wrist-worn photoplethysmography (PPG) enables continuous monitoring of cardiopulmonary physiology, but reliable heart rate (HR) and respiratory rate (...

Jun 29 2026 2606.30156v1
When Does Synthetic CT Transfer? A Label-Free Donor/Host Diagnostic for Medical Vision-Language Model Routing on Real Lung CT

A synthetic measurement of model competence is useful only if it survives the move to real data, yet the real labels that would verify it are exactly ...

Jun 28 2026 2606.29232v1
A Natural Experiment Reveals Clinically Essential and Compliance-Driven Nursing Documentation

Despite contributing substantially to clinician burnout, nursing documentation lacks empirical evidence distinguishing clinically essential from admin...

ADVISE: A Machine Learning Framework for Early Recognition of a Surrogate Marker for Ventilator-Associated Pneumonia Using Routinely Collected Critical Care Data

BackgroundVentilator-associated pneumonia (VAP) is the most frequent nosocomial infection in critical care, affecting 20-36% of mechanically ventilate...

KG-TRACE: A Neuro-Symbolic Framework for Mechanistic Grounding in Antimicrobial Resistance Prediction

While WGS-based AMR prediction has reached high accuracy, existing models lack a mechanism to ground neural attributions in established biological pat...

Jun 24 2026 2606.26179v1
Pulmonary Embolism Risk Stratification from CTPA and Medical Records: Vascular Graphs Are Not All You Need

Risk stratification for pulmonary embolism (PE) is critical for clinical decision-making. Stratification guidelines are based on patient medical recor...

Jun 24 2026 2606.25956v1
MorVess: Morphology-Aware Pulmonary Vessel Segmentation Network

Accurate pulmonary vessel segmentation remains challenging due to the sparse, tortuous, and multi-scale nature of vascular structures, where small bra...

Jun 23 2026 2606.24214v1
Symptom-based phenotype discovery in motor neuron disease using natural language processing of electronic health records

Background: Motor neuron disease (MND) is a fatal neurodegenerative condition with significant clinical heterogeneity that is incompletely captured by...

Development of a Novel Risk Prediction Model for Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD): A Longitudinal Study

Background: Interstitial lung disease (ILD) is one of the most common and potentially most devastating extra-articular complication of rheumatoid arth...

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