Pulmonology

Latest AI and machine learning research in pulmonology for healthcare professionals.

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Optimizing 2D Input Representations and Sub-phase Fusion Strategies for Differential Diagnosis of Asthma and COPD Using CNN- and GRU-Based Networks

This study aims to explore the performance of the VAR model in comparison with mel-frequency cepstral coefficient (MFCC) matrices and log-mel spectrograms using deep learning. In pulmonary sound classification, spectrogram-based representations suffer from inconsistent temporal dimensions due to varying respiratory cycle durations. Along with traditional trimming/zero-padding, adaptive-length wind...

Jun 9 2026 2606.10972v1

OncoTraj: a public benchmark for longitudinal resistance prediction in EGFR-mutant non-small-cell lung cancer on osimertinib

Resistance to first-line osimertinib in EGFR-mutant non-small-cell lung cancer (NSCLC) is the canonical example of predictable clonal evolution under therapeutic pressure, yet no public benchmark exists for training or evaluating computational models on the corresponding longitudinal patient trajectories. We introduce OncoTraj, a public benchmark of 813 EGFR-mutant NSCLC patients receiving first-l...

Jun 9 2026 2606.11144v1
Compositional and interpretable representation of histology using AI foundation models and sparse autoencoders

Light microscopy of tissue sections stained with hematoxylin and eosin (H&E) has been the foundation of histopathology for over 150 years and remains ...

When is 3D Worth It? A Resource-Performance Frontier for CNNs and Transformers in Lung CT

Three-dimensional models are widely assumed preferable for volumetric medical imaging, yet their practical value depends on whether performance gains ...

Jun 5 2026 2606.06950v1
A robust PPG foundation model using multimodal physiological supervision

Photoplethysmography (PPG), a non-invasive measure of changes in blood volume, is widely used in both wearable devices and clinical settings. Recent P...

Jun 5 2026 2606.07365v1
PAMF: Prior-Aware Multimodal Fusion for Incomplete Time Series Data

In healthcare, multimodal time series tasks often operate on incomplete observations in practice, for example when ECG segments are lost because elect...

Jun 4 2026 2606.06328v1
Automatic Speech Recognition and Phonetics-Informed Sentence Design for Spastic Dysarthria Detection and Corticobulbar Lesion Localization

Spastic dysarthria diagnosis through subjective neurologist auditory-perceptual assessment remains standard practice despite known inaccuracy. To addr...

Agentic Chart Review from Longitudinal Clinical Notes: a Lung Cancer Guideline Concordance Use Case

Clinical chart abstraction extracts structured patient variables from longitudinal clinical notes but is labor-intensive and difficult to scale. We ev...

Performance of Vision-Language Models for Zero-Shot Lung Nodule Detection on Chest Radiographs

Background and Objectives: The ability of vision-language models (VLMs) to detect lung nodules on chest radiographs remains uncertain. This retrospect...

SchistoTrackNet: machine learning for diagnosis of schistosomiasis-associated periportal fibrosis from ultrasound images

Liver fibrosis is a major cause of death in low- and middle-income country contexts. In rural, poor areas of sub-Saharan Africa, schistosomiasis is an...

SchistoTrackVideoNet: multilabel deep learning-based classification of schistosomal periportal fibrosis from ultrasound video

Schistosomiasis causes a complex, difficult to diagnose form of liver fibrosis with high rates of life-threatening morbidity in resource-poor settings...

UMITIC: An unsupervised framework for the joint characterization of cellular phenotypes and spatial neighborhoods in multiplex and hyperplex immunofluorescence imaging data

Multiplexed imaging technologies enable the simultaneous measurement of dozens of protein markers while preserving context, providing a high-resolutio...

Segmental Lung Sound Analysis in Obstructive Lung Diseases Using Electronic Stethoscope; a protocol to establish an acoustic repository

Introduction Obstructive lung diseases (OLDs) are responsible for high rates of illness and death worldwide. Inflammation, chronic airflow limitation,...

Future Pandemics: AI-Designed Diagnostic Assays for Detection of Andes Orthohantavirus (ANDV) Associated with the 2026 MV Hondius Outbreak

Andes orthohantavirus (ANDV), the primary etiological agent of hantavirus pulmonary syndrome (HPS) in South America, is uniquely capable of limited hu...

An LSEC-focused computational drug repurposing platform for liver fibrosis: Identification of vorinostat and other LSEC-protective candidates

Liver sinusoidal endothelial cells (LSECs) are increasingly recognized as a critical yet underexplored cell type in anti-fibrotic drug development. Th...

Development and validation of a dynamic risk stratification tool for predicting multidrug-resistant bacterial infections in ICU patients: A clinical prediction model and web-based calculator

Background: Multi-drug resistant Bacterial (MDRB) Infections in the intensive care units (ICUs) substantially elevate patient mortality, prolong hospi...

Prospective evaluation of multimodal respiratory failure prediction: Do chest X-rays improve performance beyond EHR signals?

Early prediction of respiratory failure is critical for timely clinical intervention in intensive care units. Existing electronic health record (EHR)-...

May 25 2026 2605.26255v1
Genomic Diagnostics for Drug-Resistant Mycobacterium tuberculosis: Computational Prediction of Antimicrobial Resistance

Tuberculosis remains a leading cause of infectious disease mortality, and the continued emergence of drug-resistant Mycobacterium tuberculosis strains...

How Far Has AI Come in Liver Fibrosis Staging? A Large-Scale Real-World Dataset and Benchmark

Despite years of methodological progress, how far AI has come in liver fibrosis staging has never been systematically evaluated under the heterogeneou...

May 25 2026 2605.25595v1
A Clinically Validated Foundation Model for Comprehensive Lung Pathology Interpretation

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specif...

May 25 2026 2605.25878v1
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