Pulmonology

Latest AI and machine learning research in pulmonology for healthcare professionals.

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Attention-based multiple instance learning for predominant growth pattern prediction in lung adenocarcinoma wsi using foundation models

Lung adenocarcinoma (LUAD) grading depends on accurately identifying growth patterns, which are indicators of prognosis and can influence treatment decisions. Common deep learning approaches to determine the predominant pattern rely on patch-level classification or segmentation, requiring extensive annotations. This study proposes an attention-based multiple instance learning (ABMIL) framework to ...

Apr 23 2026 2604.21530v1

Data-Driven Open-Loop Simulation for Digital-Twin Operator Decision Support in Wastewater Treatment

Wastewater treatment plants (WWTPs) need digital-twin-style decision support tools that can simulate plant response under prescribed control plans, tolerate irregular and missing sensing, and remain informative over 12-36 h planning horizons. Meeting these requirements with full-scale plant data remains an open engineering-AI challenge. We present CCSS-RS, a controlled continuous-time state-space ...

Apr 22 2026 2604.20935v1
ProtoCLIP: Prototype-Aligned Latent Refinement for Robust Zero-Shot Chest X-Ray Classification

Zero-shot vision-language models (VLMs) have shown promise for chest radiograph classification, but their performance is often limited by confounding ...

Apr 20 2026 2604.18444v1
Dual-Modal Lung Cancer AI: Interpretable Radiology and Microscopy with Clinical Risk Integration

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential fo...

Apr 17 2026 2604.16104v1
Inflammatory Biomarkers & Interpretable ML for SAP Risk Stratification in AIS Patients Undergoing Bridging Therapy

Stroke-associated pneumonia (SAP) is a common, severe complication in acute ischemic stroke (AIS) patients receiving bridging therapy (intravenous thr...

Automated Detection of Dental Caries and Bone Loss on Periapical and Bitewing Radiographs using a YOLO Based Deep Learning Model

BackgroundDental caries and periodontal disease represent the most prevalent global oral health conditions, collectively affecting several billion peo...

Preoperative CT-Based Habitat Radiomics Classifiers Predict Recurrence in Non-Small Cell Lung Cancer

Objectives: Among surgically resected non-small cell lung cancer (NSCLC) patients with similar stage and histopathological characteristics, there is v...

A generative AI framework for disease-specific lung microtissue bioengineering

Generative Lung Architecture Modeling (GLAM) is an integrated bioengineering framework that couples high-resolution three-dimensional tissue imaging w...

Testing and Estimating Causal Treatment Effect Heterogeneity in Observational Studies via Revised Deep Semiparametric Regression: A Lung Transplant Case Study

Lung transplantation programs must decide when bilateral lung transplantation (BLT) offers meaningful functional benefit over single lung transplantat...

CBAM-Enhanced DenseNet121 for Multi-Class Chest X-Ray Classification with Grad-CAM Explainability

Pneumonia remains a leading cause of childhood mortality worldwide, with a heavy burden in low-resource settings such as Bangladesh where radiologist ...

Apr 14 2026 2604.12305v1
Virtual Spectral Decomposition with Dendritic Tile Selection: An Explainable AI Framework for Multimodal Tissue Composition Analysis and Immune Phenotyping Across Pancreatic, Lung, and Breast Cancer

Background: Current deep learning models in computational pathology, radiology, and digital pathology produce opaque predictions that lack the explain...

TB-Bench: A Systematic Benchmark of Machine Learning and Deep Learning Methods for Second-Line TB Drug Resistance Prediction

Drug-resistant tuberculosis (TB), characterized by prolonged treatment regimens and suboptimal treatment outcomes, remains a major obstacle to global ...

SiMing-Bench: Evaluating Procedural Correctness from Continuous Interactions in Clinical Skill Videos

Current video benchmarks for multimodal large language models (MLLMs) focus on event recognition, temporal ordering, and long-context recall, but over...

Apr 10 2026 2604.09037v1
DSVTLA: Deep Swin Vision Transformer-Based Transfer Learning Architecture for Multi-Type Cancer Histopathological Cancer Image Classification

In this study, we proposed a deep Swin-Vision Transformer-based transfer learning architecture for robust multi-cancer histopathological image classif...

Apr 10 2026 2604.09468v1
Weakly-Supervised Lung Nodule Segmentation via Training-Free Guidance of 3D Rectified Flow

Dense annotations, such as segmentation masks, are expensive and time-consuming to obtain, especially for 3D medical images where expert voxel-wise la...

Apr 9 2026 2604.08313v1
Time-driven Survival Analysis from FDG-PET/CT in Non-Small Cell Lung Cancer

Purpose: Automated medical image-based prediction of clinical outcomes, such as overall survival (OS), has great potential in improving patient progno...

Apr 8 2026 2604.06885v1
CRISP: Rank-Guided Iterative Squeezing for Robust Medical Image Segmentation under Domain Shift

Distribution shift in medical imaging remains a central bottleneck for the clinical translation of medical AI. Failure to address it can lead to sever...

Apr 7 2026 2604.05409v1
Unifying VLM-Guided Flow Matching and Spectral Anomaly Detection for Interpretable Veterinary Diagnosis

Automatic diagnosis of canine pneumothorax is challenged by data scarcity and the need for trustworthy models. To address this, we first introduce a p...

Apr 7 2026 2604.05482v1
Semantic-Topological Graph Reasoning for Language-Guided Pulmonary Screening

Medical image segmentation driven by free-text clinical instructions is a critical frontier in computer-aided diagnosis. However, existing multimodal ...

Apr 7 2026 2604.05620v1
Clinician-Informed Feature Engineering Improves Machine Learning Assignment of Molecular Endotypes in the Intensive Care Unit

Objective: To develop a workflow that transforms electronic health record data into machine learning-ready features for molecular endotype assignment ...

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