Pulmonology

Hybrid Design of Isonicotinic Acid Hydrazide Derivatives: Machine Learning Studies, Synthesis and Biological Evaluation of their Antituberculosis Activity.

BACKGROUND: Tuberculosis (TB) is an infection disease caused by Mycobacterium tuberculosis (Mtb) bacteria. One of the main causes of mortality from TB is the problem of Mtb resistance to known drugs.

iATP: A Sequence Based Method for Identifying Anti-tubercular Peptides.

BACKGROUND: Tuberculosis is one of the biggest threats to human health. Recent studies have demonstrated that anti-tubercular peptides are promising candidates for the discovery of new anti-tubercular drugs. Since experimental methods are still labor intensive, it is highly desirable to develop automatic computational methods to identify anti-tubercular peptides from the huge amount of natural and...

Recent Advancement in Predicting Subcellular Localization of Mycobacterial Protein with Machine Learning Methods.

Mycobacterium tuberculosis (MTB) can cause the terrible tuberculosis (TB), which is reported as one of the most dreadful epidemics. Although many bioc...

[Artificial intelligence in lung imaging].

CLINICAL/METHODICAL ISSUE: Artificial intelligence (AI) has the potential to improve diagnostic accuracy and management in patients with lung disease ...

Overview of Computer Aided Detection and Computer Aided Diagnosis Systems for Lung Nodule Detection in Computed Tomography.

BACKGROUND: Lung cancer has become a major cause of cancer-related deaths. Detection of potentially malignant lung nodules is essential for the early ...

Opportunities for machine learning to transform care for people with cystic fibrosis.

Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation.

Image-based computer-aided diagnosis (CAD) algorithms by the use of convolutional neural network (CNN) which do not require the image-feature extracto...

Automated sample preparation with SP3 for low-input clinical proteomics.

High-throughput and streamlined workflows are essential in clinical proteomics for standardized processing of samples from a variety of sources, inclu...

Application and Development of Artificial Intelligence and Intelligent Disease Diagnosis.

With the continuous development of artificial intelligence (AI) technology, big data-supported AI technology with considerable computer and learning c...

[Diagnosis of malignant pleural effusions using convolutional neural networks by the morphometric image analysis of facies of pleural exudate].

OBJECTIVE: To estimate the possibility of diagnosis of malignant pleural effusion using convolutional neural networks of facies images of pleural exud...

Deep learning-based CAD schemes for the detection and classification of lung nodules from CT images: A survey.

BACKGROUND: Lung cancer is the most common cancer in the world. Computed tomography (CT) is the standard medical imaging modality for early lung nodul...

Developing and verifying automatic detection of active pulmonary tuberculosis from multi-slice spiral CT images based on deep learning.

OBJECTIVE: Diagnosis of tuberculosis (TB) in multi-slice spiral computed tomography (CT) images is a difficult task in many TB prevalent locations in ...

Multi-level 3D Densenets for False-positive Reduction in Lung Nodule Detection Based on Chest Computed Tomography.

OBJECTIVE: False-positive nodule reduction is a crucial part of a computer-aided detection (CADe) system, which assists radiologists in accurate lung ...

[Quantitative Analysis of Emphysema in Ultra-high-resolution CT by Using Deep Learning Reconstruction: Comparison with Hybrid Iterative Reconstruction].

PURPOSE: The noise generated in ultra-high-resolution computed tomography (U-HRCT) images affects the quantitative analysis of emphysema. In this stud...

Possible Protective Mechanisms of Coenzyme Q10 Action on Spermatozoa During Cryopreservation or Cooled-Stored Condition.

Artificial insemination (AI) with frozen or cooled-stored semen plays a key role in the widespread distribution of germplasm of elite livestock resour...

Incubation with Cholesterol-loaded Cyclodextrin and Subsequent Dilution in Partially Deoxygenated Extender Improves the Freezability of Cross-bred Bull Sperm.

BACKGROUND: The cryopreservation process induces osmotic stress, membrane changes and production of reactive oxygen species resulting in damage to the...

[Pulmonary nodule detection method based on convolutional neural network].

A method was proposed to detect pulmonary nodules in low-dose computed tomography (CT) images by two-dimensional convolutional neural network under th...

Computer-Aided Diagnosis (CAD) of Pulmonary Nodule of Thoracic CT Image Using Transfer Learning.

Computer-aided diagnosis (CAD) has already been widely used in medical image processing. We recently make another trial to implement convolutional neu...

Lung Nodule Detection in CT Images Using a Raw Patch-Based Convolutional Neural Network.

Remarkable progress has been made in image classification and segmentation, due to the recent study of deep convolutional neural networks (CNNs). To s...

Investigation of Low-Dose CT Lung Cancer Screening Scan "Over-Range" Issue Using Machine Learning Methods.

Low-dose computed tomography (CT) lung cancer screening is recommended by the US Preventive Services Task Force for high lung cancer-risk populations....