Pulmonology

Physiological predictors of respiratory motor plasticity: A machine-learning reappraisal of phrenic motor facilitation.

Acute intermittent hypoxia (AIH)-induced phrenic long-term facilitation (pLTF) is a well-established...

Deep learning-based segmentation and quantification of pulmonary masses on apparent diffusion coefficient maps: a multicentre reproducibility study.

OBJECTIVES: To develop and validate a deep learning model for automatic segmentation of pulmonary ma...

Decoding viral evolution through integrative bioinformatics: From genomes to global health.

Bioinformatics has transformed modern virology by linking genomic variation to epidemiology, protein...

Divergent macrophage-regulated T cell states determine response to Bacillus Calmette-Guérin vaccine in high-risk bladder cancer.

BACKGROUNDPrimary therapy for high-risk bladder cancer (BCa) is repeated instillations of the tuberc...

Identification of potential MenT3 inhibitors for Mycobacterium tuberculosis using the generative artificial intelligence and SilicoXplore platform.

TCMNet: dynamic tanh enhanced 3D transformer with cascaded multiplicative fusion for pulmonary nodule detection.

Early detection of pulmonary nodules plays a critical role in improving the survival rate of patient...

Cohort vs case-control design for transformer-based prediction of asthma exacerbations in mild asthma.

Acute asthma exacerbation (AAE) is among the most serious outcomes of asthma, and accurate predictio...

Whole genome sequencing precision medicine strategy to shorten treatment for rifampicin-resistant tuberculosis (SMARTT): a pragmatic, randomised, single-blind phase 4 trial.

BACKGROUND: All patients with rifampicin-resistant tuberculosis should receive a short course of eff...

Artificial Intelligence in Systemic Sclerosis: Clinical applications, challenges, and future directions.

Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy,...

Clinical utility of BOLD-MRI in accurate diagnosis and prognostic evaluation of diabetic nephropathy: a prospective renal biopsy-based cohort study.

OBJECTIVES: To validate blood oxygen level-dependent MRI (BOLD-MRI) for non-invasive discrimination ...

Continuous Mobile Audio Monitoring for Sleep Apnea Detection.

Audio-based sleep apnea detection methods hold great potential to improve access to diagnosis, by pr...

Hybrid supervised deep learning for lung adenocarcinoma diagnosis to optimize surgical strategies.

Intraoperative frozen section pathological diagnosis of lung adenocarcinoma serves as the gold stand...

Development of machine learning and nomogram models to predict lung metastasis and prognosticate survival in breast cancer.

PURPOSE: Lung metastasis in breast cancer (BCLM) is a critical determinant of poor prognosis, occurr...

Cauchy Lotus Optimization-based feature selection and ResNet 101 based XceptionNet architecture for radiation pneumonitis prediction in lung cancer patients.

Thoracic radiotherapy for lung cancer patients followed by radiation pneumonitis (RP) has significan...

Artificial intelligence (AI)-assisted ultrasound in clinical trials: Endpoint automation, decentralized monitoring, and regulatory readiness.

Ultrasound is among the most widely used imaging modalities in clinical trials, and yet its dependen...

A Transformer-ResNet-Integrated Deep Learning Model for Digital Pathology-Based Grading and Risk Stratification of MASLD-Related Liver Fibrosis.

INTRODUCTION: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects up to 30% of ...

A Roadmap to Transform Lung Cancer Outcomes: Priorities in Biology, Therapeutic Innovation, Early Detection, Prevention and Interception.

Advances in targeted therapies, immunotherapy, and early detection have revolutionized lung cancer t...

Effective elimination of respiratory misregistration-induced attenuation correction errors in PET/CT via deep learning trained on data-driven gated PET from strictly respiratory-phase-matched PET/CT cases.

Pre-Imaging Clinical Factors Associated With Cardiac MR Image Quality Using Large Language Model-Enabled Data Extraction.

BACKGROUND: Poor cardiac MR image quality can prompt repeat examinations and hinder clinical decisio...

A motor thalamic site in humans that suppresses involuntary breathing without awareness.

Breathing is generated by brainstem respiratory networks but can be controlled and modulated by fore...

Advances in Oral Cavity Stem Cell Research Revealed through Multi-omics Analysis.

Oral stem cell research encompasses the study of dental pulp stem cells, periodontal ligament stem c...