Ophthalmology

Refractive Surgery

Latest AI and machine learning research in refractive surgery for healthcare professionals.

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The Golgi Apparatus as an Arbiter of Oncofetal Reprogramming: A Systematic Review and Meta-Analysis Linking Embryonic Germ Layer Origin to the Post-Translational Modification Landscape of Cancer

Post-translational modifications (PTMs) represent a fourth dimension of the genetic code, orchestrated by the Golgi apparatus and central to the biology of cancer. The prevailing paradigm of oncofetal reprogramming posits that cancer cells reactivate embryonic developmental programs to drive tumorigenesis; however, the lineage-specific nature of this reversion remains incompletely defined. This re...

Machine Learning for Paediatric Related Decision Support in Emergency Care – A UK and Ireland Network Survey Study of Emergency Staff

There is great potential for artificial Intelligence (AI) and machine learning (ML) to support decision making in emergency departments (ED), however their implementation in routine clinical practice remains limited. The objective of this study was to assess the understanding, experience and perspectives of the wider paediatric ED workforce (nurses, doctors and support staff) in the United Kingdom...

Not So Fast, I’m Serofast: Using Innovative Education Techniques to Drive Management of People with Syphilis

An increase in syphilis cases in the United States and the global shortage of Benzathine Penicillin G (BPG) calls for evidence-based optimization. Con...

A scoping review of the application of artificial intelligence for the analysis of adverse drug events in clinical research

The early detection of adverse drug events (ADEs) became a critical issue in clinical research after the thalidomide disaster in 1961, which resulted ...

Explainable machine learning for post PKR surgery follow-up

Photorefractive Keratectomy (PRK) is a widely used laser-assisted refractive surgical technique. In some cases, it leads to temporary subepithelial in...

Predicting coronary artery abnormalities in Kawasaki disease: Model development and external validation

Kawasaki disease (KD) is an acute, pediatric vasculitis associated with coronary artery abnormality (CAA) development. Echocardiography at month 1 pos...

Risk Prediction Modelling of 30-day all-cause mortality following percutaneous coronary intervention in an Australian population: Leveraging Machine Learning

Pre-procedural risk prediction of 30-day all-cause mortality after percutaneous coronary intervention (PCI) aids in clinical decision-making and bench...

Comparative Analysis of Long COVID and Post-Vaccination Syndrome: A Cross-Sectional Study of Clinical Symptoms and Machine Learning-Based Differentiation

Long COVID is a well-documented post-viral syndrome, while post-vaccination syndrome (PVS) remains poorly characterized. Understanding their similarit...

Neuroimaging Correlates of Post-Stroke Pain After Ischemic Stroke: Secondary Analysis of the INSPiRE-TMS Trial

Post-stroke pain (PSP) affects nearly half of stroke survivors, severely compromising quality of life. The causes of PSP remain underexplored, althoug...

Symbolic Regression for Mycophenolic Acid Dosage Prediction in Kidney Transplant Recipients

Chronic kidney disease (CKD) affects millions worldwide and often progresses to end-stage renal disease (ESRD), for which kidney transplantation remai...

Responsible AI in Action: Planning through Implementation of a Mortality Model for Palliative Care

Interest in the use of prediction models to support referrals to palliative care is surging. Few high-performing models have been developed, implement...

Clinical evaluation of a natural language processing system for assisting structured diagnosis recording at the point of care: MiADE (Medical Information AI Data Extractor)

Structured recording of key information such as diagnoses is essential for safe, efficient patient care, but is currently done incompletely because it...

Predicting Rejection Risk in Heart Transplantation: An Integrated Clinical–Histopathologic Framework for Personalized Post-Transplant Care

Cardiac allograft rejection (CAR) remains the leading cause of early graft failure after heart transplantation (HT). Current diagnostics, including hi...

A systematic review of early neuroimaging and neurophysiological biomarkers for post-stroke mobility prognostication

Accurate prognostication of mobility outcomes is essential to guide rehabilitation and manage patient expectations. The prognostic utility of neuroima...

Machine Learning-Driven Decision-Support System for Nursing Risk Assessment in Post-Discharge Care: A Design Science Approach

Hospital readmissions represent a persistent challenge for healthcare systems, often stemming from inadequate post-discharge monitoring. This study pr...

Dietary Macronutrient Intake and the Gut Microbiome in Adults Undergoing Bariatric Surgery for Obesity

Limited information linking dietary intake to gut metagenomic data in bariatric surgery patients is available. We examined whether there were correlat...

Early Identification of High-Risk Individuals for Mortality after Lung Transplantation: A Retrospective Cohort Study with Topological Transformers

Lung transplantation remains the only definitive treatment for patients with end-stage respiratory failure; however, it is burdened by a substantial r...

Risk assessment in cardiac surgery: Exploring machine learning and laboratory indices as adjunctive tools

Post-operative outcomes of cardiovascular surgery vary greatly among patients for a variety of reasons. While the specific reasons are often multifact...

Falls in Assisted Living Facilities: Can AI improve documentation and reduce injury?

Falls among elderly residents in assisted living facilities (ALFs) are prevalent, costly, and frequently under-documented. AUGi, a wall-mounted device...

Multi-branch convolutional neural network using intracranial EEG high frequency oscillation features for predicting post-surgical seizure outcomes

Pathological high-frequency oscillations (HFOs 80-600 Hz) in intracranial EEG distinguish epileptogenic cortex. However, it is uncertain whether utili...

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