Latest AI and machine learning research in rheumatology for healthcare professionals.
Articular cartilage is a porous, soft tissue present in the synovial joints that distributes the load and lubricate the joint for smooth body movements. Arthritis or joint diseases lead to cartilage degeneration. However, the triggering factors of these joint diseases are still strongly debated, with uncertainties about the key mechanisms and the mechanochemical and biological interactions that ma...
Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune demyelinating disease characterized by recurrent neuroinflammation and disability. Microglial activation plays a critical role in NMOSD pathogenesis, yet the mechanisms regulating its temporal dynamics remain poorly understood. The interplay between apolipoprotein E (APOE) and triggering receptor expressed on myeloid cells 2 (TR...
PURPOSE: Some patients with neovascular age-related macular degeneration (nAMD) have persistent signs of exudation under treatment with intravitreal i...
Numerous neurological conditions impact the brain, spinal cord, and nerves, including neurodegenerative diseases such as Alzheimer's and Parkinson's d...
Microglial activation is linked to neuroinflammation in neuropathic pain. Recently, microglia-mediated synaptic pruning has received mounting attentio...
Bio-instructive materials that intrinsically inhibit biofilm formation have significant anti-biofouling potential in industrial and healthcare setting...
A kind of covalent modification known as post-translational modification (PTM) happens following the biosynthesis process, which is important in cell ...
Melioidosis, a fatal tropical disease, presents a wide array of clinical manifestations, including abscesses, pneumonia, septic shock, bacteraemia, os...
The brain growth spurt (BGS) represents a pivotal window in neurodevelopment, defined by rapid neurogenesis, heightened synaptogenesis, and the dynami...
OBJECTIVE: Alzheimer's disease poses a significant threat to human health. Currenttherapeutic medicines, while alleviate symptoms, fail to reverse the...
OBJECTIVES: We aimed to evaluate similarities and variations of information provided by Large Language Models (LLMs) across diverse world regions by a...
OBJECTIVES: Systemic sclerosis (SSc) is a complex autoimmune disease with both known and unidentified genetic contributors. While genome-wide associat...
Systemic lupus erythematosus (SLE), a multifaceted autoimmune disorder, has lupus nephritis (LN) as one of its grave complications and is strongly ass...
Myocardial fibrosis, a hallmark of heart failure (HF), contributes to disease progression and mortality by impairing cardiac function. Despite the ide...
BACKGROUND: Kawasaki disease (KD), a pediatric systemic vasculitis, lacks reliable diagnostic biomarkers and exhibits immune heterogeneity, complicati...
OBJECTIVE: To systematically review all existing Sjögren disease (SjD)-related instruments reported in clinical trials for SjD.
Elucidating the anti-tumor role of tumor-draining lymph nodes (tdLNs) in patients could offer critical mechanistic insight and shift therapeutic strat...
Cytokine receptors play a pivotal role in mediating the immune response and are critical in cytokine storms, which underlie the pathogenesis of condit...
The first session of the 2025 European Society of Toxicologic Pathology (ESTP) Congress reviewed routine and specialized methods for microscopic evalu...
Flavones, recognized as "privileged scaffolds" in drug discovery, hold significant promise as anti-cancer agents. This study aimed to develop a quanti...