Rheumatology

Continuous Estimation of Human Joint Angles From sEMG Using a Multi-Feature Temporal Convolutional Attention-Based Network.

Intention recognition based on surface electromyography (sEMG) signals is pivotal in human-machine interaction (HMI), where continuous motion estimation with high accuracy has been the challenge. The convolutional neural network (CNN) possesses excellent feature extraction capability. Still, it is difficult for ordinary CNN to explore the dependencies of time-series data, so most researchers adopt...

RNADSN: Transfer-Learning 5-Methyluridine (mU) Modification on mRNAs from Common Features of tRNA.

One of the most abundant non-canonical bases widely occurring on various RNA molecules is 5-methyluridine (m5U). Recent studies have revealed its influences on the development of breast cancer, systemic lupus erythematosus, and the regulation of stress responses. The accurate identification of mU sites is crucial for understanding their biological functions. We propose RNADSN, the first transfer l...

Virtual disease landscape using mechanics-informed machine learning: Application to esophageal disorders.

Esophageal disorders are related to the mechanical properties and function of the esophageal wall. Therefore, to understand the underlying fundamental...

Computational model of the full-length TSH receptor.

(GPCR)The receptor for TSH receptor (TSHR), a G protein coupled receptor (GPCR), is of particular interest as the primary antigen in autoimmune hypert...

Complementary Memtransistor-Based Multilayer Neural Networks for Online Supervised Learning Through (Anti-)Spike-Timing-Dependent Plasticity.

We propose a complete hardware-based architecture of multilayer neural networks (MNNs), including electronic synapses, neurons, and periphery circuitr...

Modeling and insights into the structural characteristics of drug-induced autoimmune diseases.

The incidence and complexity of drug-induced autoimmune diseases (DIAD) have been on the rise in recent years, which may lead to serious or fatal cons...

De novo design of anti-tuberculosis agents using a structure-based deep learning method.

Mycobacterium tuberculosis (Mtb) is a pathogen of major concern due to its ability to withstand both first- and second-line antibiotics, leading to dr...

Shared subspace-based radial basis function neural network for identifying ncRNAs subcellular localization.

Non-coding RNAs (ncRNAs) play an important role in revealing the mechanism of human disease for anti-tumor and anti-virus substances. Detecting subcel...

High-resolution knee plain radiography image synthesis using style generative adversarial network adaptive discriminator augmentation.

In this retrospective study, 10,000 anteroposterior (AP) radiography of the knee from a single institution was used to create medical data set that ar...

Design and implementation of an adaptive fuzzy sliding mode controller for drug delivery in treatment of vascular cancer tumours and its optimisation using genetic algorithm tool.

In this paper, the side effects of drug therapy in the process of cancer treatment are reduced by designing two optimal non-linear controllers. The re...

Comparing two machine learning approaches in predicting lupus hospitalization using longitudinal data.

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by flares ranging from mild to life-threatening. Severe flares ...

From real-world electronic health record data to real-world results using artificial intelligence.

With the worldwide digitalisation of medical records, electronic health records (EHRs) have become an increasingly important source of real-world data...

Deep Learning-Based Medical Data Association Rules to Explore the Connectivity and Regulation Mechanism of miRNA-mRNA Network in Myocarditis.

Acute, chronic myocarditis as myocardial localized or diffuse inflammation lesions is usually involving cardiac function in patients with severe adver...

HEp-2 image classification using a multi-class and multiple-binary classifier.

In medicine, identifying the indirect immunofluorescence of human epithelial type 2 (HEp-2) cells plays a decisive role in the diagnosis of autoimmune...

A systematic review of robot-assisted anti-reflux surgery to examine reporting standards.

Robot-assisted anti-reflux surgery (RA-ARS) is increasingly being used to treat refractory gastro-oesophageal reflux disease. The IDEAL (Idea, Develop...

Prediction of the Lotus Effect on Solid Surfaces by Machine Learning.

Superhydrophobic surfaces with the "lotus effect" have wide applications in daily life and industry, such as self-cleaning, anti-freezing, and anti-co...

Robotic single port anti-reflux surgery: Initial worldwide experience of two cases with a novel surgical approach to treat gastroesophageal reflux disease.

INTRODUCTION: To date, no anti-reflux operations have been reported with the new da Vinci Single-Port (single port (SP)) robotic platform. We aimed to...

Development of GBRT Model as a Novel and Robust Mathematical Model to Predict and Optimize the Solubility of Decitabine as an Anti-Cancer Drug.

The efficient production of solid-dosage oral formulations using eco-friendly supercritical solvents is known as a breakthrough technology towards dev...

Recent advances in the use of machine learning and artificial intelligence to improve diagnosis, predict flares, and enrich clinical trials in lupus.

PURPOSE OF REVIEW: Machine learning is a computational tool that is increasingly used for the analysis of medical data and has provided the promise of...

Anti-Colorectal Cancer Effects of (Bull.: Fr.) P. Karst. Spore Powder through Regulation of Gut Microbiota-Mediated JAK/STAT Signaling.

(Bull.: Fr.) P. Karst. spore powder (IHS) contains polyphenols and triterpenoids with pharmacological effects. Here, we analyzed its composition, and...