Rheumatology

Latest AI and machine learning research in rheumatology for healthcare professionals.

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Showing 1401-1420 of 6,049 articles

An LSEC-focused computational drug repurposing platform for liver fibrosis: Identification of vorinostat and other LSEC-protective candidates

Liver sinusoidal endothelial cells (LSECs) are increasingly recognized as a critical yet underexplored cell type in anti-fibrotic drug development. This study presents a computational drug screening platform integrating LSEC-specific transcriptomic analysis across simple steatosis, fibrotic nonalcoholic steatohepatitis (NASH), and cirrhosis, with tiered gene signature selection combining machine l...

Assessing the reliability of immunofluorescence image analysis with artificial intelligence

In view of the outstanding progress of machine learning (ML) and growing cost of health systems, it is a current challenge to incorporate artificial intelligence tools into actual medical practice. Here we explored the feasibility and reliability of using machine learning to perform an important immunological investigation that currently requires experienced biologists : Anti-nuclear cytoplasmic a...

Artificial intelligence-generated digital Romberg test for peripheral neuropathy monitoring.

Background and Objectives Patients with peripheral neuropathies (PN) commonly exhibit balance impairment. In clinical practice, balance is typically a...

Segmentation and profile-based classification of movement strategies from animal tracking data

1. Classifying animal movement strategies from GPS tracking data is essential for understanding space use, population dynamics and conservation planni...

Using Deep Learning Models of Gene Regulation to Guide Drug Prioritization

Drug repurposing offers a cost-effective strategy to accelerate therapeutic discovery, but most computational approaches fail to model noncoding genet...

ConvergeCELL: An end-to-end platform from patient transcriptomics to therapeutic hypotheses

Translating transcriptomic data into therapeutic hypotheses remains fragmented and labor-intensive. Here we present ConvergeCELL, a platform combining...

RAM-H1200: A Unified Evaluation and Dataset on Hand Radiographs for Rheumatoid Arthritis

Rheumatoid arthritis (RA) assessment from hand radiographs requires multi-level analysis and modeling of anatomical structures and fine-grained local ...

May 7 2026 2605.05616v1
Diverse Sampling in Diffusion Models with Marginal Preserving Particle Guidance

We present EDDY (Exact-marginal Diversification via Divergence-free dYnamics), a guidance mechanism for diffusion and flow matching models that promot...

May 7 2026 2605.06553v1
An electrocardiogram-based machine learning model for distinguishing complete Kawasaki disease.

Kawasaki disease (KD) is a systemic vasculitis in young children, and early diagnosis remains challenging when clinical features are incomplete or ove...

Do Larger Models Really Win in Drug Discovery?A Benchmark Assessment of Model Scaling in AI-Driven Molecular Property and Activity Prediction

The rapid growth of molecular foundation models and general-purpose large language models has encouraged a scale-centric view of artificial intelligen...

Impact of Age Specialized Models for Hypoglycemia Classification

Disease progression varies with age and is influenced by underlying genetic, biochemical, and hormonal etiologies, suggesting the need for tailored mo...

Apr 26 2026 2604.23732v1
Semaglutide is associated with improved breast cancer survival, lower metastatic burden, and a dose-survival relationship uncoupled from weight-loss magnitude

Metabolic dysfunction is increasingly recognized as a risk factor for poor outcomes in breast cancer, but whether incretin-based therapies confer surv...

Multimodal prediction of visual improvement in diabetic macular edema using real-world electronic health records and optical coherence tomography images

Multimodal learning has the potential to improve clinical prediction by integrating complementary data sources, but the incremental value of imaging b...

Performance Anomaly Detection in Athletics: A Benchmarking System with Visual Analytics

Anti-doping programs rely on biological testing to detect performance-enhancing drugs, but such testing costs over $800 per sample and is limited by s...

Apr 23 2026 2604.21953v1
MetaCloak-JPEG: JPEG-Robust Adversarial Perturbation for Preventing Unauthorized DreamBooth-Based Deepfake Generation

The rapid progress of subject-driven text-to-image synthesis, and in particular DreamBooth, has enabled a consent-free deepfake pipeline: an adversary...

Apr 20 2026 2604.18537v1
ORION: An agentic reasoning construct for the analysis of complex human immune profiling

The capacity to generate high-dimensional biological datasets has outpaced the ability to interpret them. Technologies such as phage immunoprecipitati...

Robust by Design: A Continuous Monitoring and Data Integration Framework for Medical AI

Adaptive medical AI models often face performance drops in dynamic clinical environments due to data drift. We propose an autonomous continuous monito...

Apr 10 2026 2604.09009v1
Domain-generalizable Face Anti-Spoofing with Patch-based Multi-tasking and Artifact Pattern Conversion

Face Anti-Spoofing (FAS) algorithms, designed to secure face recognition systems against spoofing, struggle with limited dataset diversity, impairing ...

Apr 10 2026 2604.09018v1
Shortcut Learning in Glomerular AI: Adversarial Penalties Hurt, Entropy Helps

Stain variability is a pervasive source of distribution shift and potential shortcut learning in renal pathology AI. We ask whether lupus nephritis gl...

Apr 9 2026 2604.07936v1
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