Latest AI and machine learning research in rheumatology for healthcare professionals.
Easy and accessible biomarkers to predict response to immune checkpoint inhibition (ICI)-treated melanoma are limited. To evaluate artificial intelligence (AI) detected tumor-infiltrating lymphocytes (TILs) on pretreatment melanoma metastases as a biomarker for response and survival in ICI-treated patients. Multicenter cohort study including patients with advanced melanoma treated with first-line ...
Coeliac disease, an autoimmune disorder affecting approximately 1% of the global population, is typically diagnosed on duodenal biopsy. However, inter-pathologist agreement on coeliac disease diagnosis is only 80%. Existing machine learning solutions designed to improve coeliac disease diagnosis often lack interpretability, which is essential for building trust and enabling widespread clinical ado...
Myasthenia gravis (MG) is a rare autoimmune neuromuscular disease. Clinical trials with rigorously collected data, especially for rare diseases, provi...
Multiple Sclerosis (MS) is a chronic autoimmune disorder of the central nervous system that can lead to significant neurological disability. Retinal i...
Large Language Models (LLMs) are increasingly deployed in clinical settings for tasks ranging from patient communication to decision support. While th...
Epilepsy affects over 50 million people worldwide, with anti-seizure medications (ASMs) as the primary treatment for seizure control. However, ASM sel...
Kawasaki disease (KD) is an acute, pediatric vasculitis associated with coronary artery abnormality (CAA) development. Echocardiography at month 1 pos...
Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches frequently focus on single disease ...
Automated thalamic nuclear segmentation has contributed towards a shift in neuroimaging analyses from treating the thalamus as a homogeneous, passive ...
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. Early detection of the prodromal phase could enable timely inte...
Personalized treatment in psoriatic arthritis (PsA) remains challenging, particularly in guiding dose escalation decisions. We applied a causal machin...
Despite the availability of more than 20 anti-seizure medications (ASMs), approximately half of patients with newly diagnosed epilepsy fail their firs...
Diabetes mellitus (DM) is a major risk factor for acquiring infections. Metformin, the first-line treatment for type 2 DM, is associated with benefici...
Psychotropic medications are commonly used for children with neurodevelopmental conditions, but their effectiveness varies, making treatment selection...
Arachnoiditis, a painful and potentially disabling neurological condition, results from persistent inflammation of the spinal cord pia-arachnoid membr...
MRI-derived organ and tissue volumes are powerful endophenotypes for studying complex disease, but their availability is limited by cost and throughpu...
Diabetes Mellitus (DM) is a metabolic disorder characterized by hyperglycemia, with type 1 characterized as an autoimmune destruction of pancreatic be...
Regular imaging by conventional radiography to assess for joint damage is a cornerstone in the management of rheumatoid arthritis (RA). Scoring system...
OBJECTIVE: The objective of this study is to compare the clinical features and survival outcomes of class IV ± V lupus nephritis (LN) patients, identi...
Kawasaki disease (KD) is an acute vasculitis that primarily affects children under five and is a leading cause of acquired heart disease in this age g...