Hospital-Based Medicine

Risk Management

Latest AI and machine learning research in risk management for healthcare professionals.

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AI-Powered Radiotherapy for Resource-Limited Settings: Advancing Cervical and Prostate Cancer Treatment Planning with the Radiation Planning Assistant (RPA)

Radiotherapy treatment planning is a resource-intensive process characterized by multiple manual steps and clinical hand-offs that contribute to treatment delays and inter-observer variability. The Radiation Planning Assistant (RPA) is a web-based platform designed to deliver automated contouring and planning approaches tailored to low-resource settings. This work expands the RPA to develop and cl...

Understanding the Relationship Between Germ Layer Origin and Cancer Therapy Response: A Systematic Review

Cancer therapeutic response patterns may be fundamentally influenced by embryonic germ layer origin. Emerging evidence suggests mesoderm-derived malignancies exhibit exceptional responsiveness to cellular immunotherapy, endoderm-derived epithelial cancers demonstrate marked sensitivity to protein signaling inhibitors, and ectoderm-derived tumors show heightened immunogenicity enabling breakthrough...

Fragile X Syndrome in Brazil: Development and Validation of a Clinical Checklist for Population Screening

Fragile X Syndrome (FXS) is the most common inherited cause of intellectual disability and syndromic autism, but diagnosis remains challenging due to ...

Accuracy of AI-assisted diagnostic tools for Schistosoma haematobium: A systematic review and meta-analysis

Urogenital schistosomiasis caused by Schistosoma haematobium remains endemic in sub-Saharan Africa. Diagnosis traditionally relies on urine microscopy...

Oxytocin Enhances Social-Emotional Reciprocity in Autism

We evaluated whether oxytocin improves social-emotional reciprocity in children and adolescents with autism spectrum disorder (ASD) by conducting a se...

Improving Doctor-Patient Communication Using Large Language Models - Results from an Experimental Study

Medical jargon poses significant barriers to patient comprehension of healthcare information, potentially affecting treatment adherence and health out...

A precision health approach to medication management in neurodevelopmental conditions: a model development and validation study using four international cohorts

Psychotropic medications are commonly used for children with neurodevelopmental conditions, but their effectiveness varies, making treatment selection...

GlioMODA: Robust Glioma Segmentation in Clinical Routine

Precise glioma segmentation in MRI is essential for accurate diagnosis, optimal treatment planning, and advancing clinical research. However, most dee...

The Promise and Peril of Large Language Models in Digital Health: GPT-4 Personalizes Cardiovascular Patient Education but Amplifies Gender Biases

Gender-neutral patient education materials often overlook critical sex-based differences in cardiovascular disease (CVD). Large Language Models (LLMs)...

Measuring the Quality of AI-Generated Clinical Notes: A Systematic Review and Experimental Benchmark of Evaluation Methods

High-quality clinical documentation is essential for safe, effective care, yet producing it is time consuming and error prone. Large language models (...

Incorporating Dietary Information to Enhance Polygenic Prediction Models with Applications to Body Mass Index and Type 2 Diabetes

Polygenic predictors can enhance screening for biomedical conditions, such as metabolism-related traits and diseases, but explain limited phenotypic v...

A double-blind, crossover, non-inferiority randomized controlled trial where primary care providers and patients compare human- and AI-generated digital health messages: the AI-CARE study protocol

Primary care is facing multiple crises, including an increase in health misinformation. Digital health messaging by primary care providers has been sh...

Shared genetic architecture of brain age gap across 30 cohorts worldwide

Deviations from normative brain ageing trajectories are linked to a wide range of adverse health outcomes. A number of brain age prediction models hav...

Explainability in action: A metric-driven assessment of local explanations for healthcare tabular models

Explainable AI (XAI) is essential in clinical machine learning, yet quantitative evaluation of explanation quality is rarely reported in a reproducibl...

GENPHIRE: Enhancing Disease Risk Prediction Using Large Language Model

Estimating an individual’s liability to a disease is a fundamental problem in genome research. By exploiting findings from genome-wide association stu...

Machine learning augmented genome-wide meta-analysis of prescription opioid use in 860,000 individuals

Opioid analgesics are widely prescribed for pain, yet individuals vary markedly in their patterns of medical opioid use, influencing the risk of prolo...

SMART (artificial intelligence enabled) DROP (diabetic retinopathy outcomes and pathways): Study protocol for diabetic retinopathy management.

INTRODUCTION: Delayed diagnosis of diabetic retinopathy (DR) remains a significant challenge, often leading to preventable blindness and visual impair...

Jan 1 2025 40388448
The role of AI in reducing maternal mortality: Current impacts and future potentials: Protocol for an analytical cross-sectional study.

BACKGROUND: Maternal and newborn mortality remains a critical public health challenge, particularly in resource-limited settings. Despite global effor...

Jan 1 2025 40367089
A Large-Scale Study on Video Action Dataset Condensation

Recently, dataset condensation has made significant progress in the image domain. Unlike images, videos possess an additional temporal dimension, wh...

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