Critical Care

Sepsis

Latest AI and machine learning research in sepsis for healthcare professionals.

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Critical-Care Subcategories: Sepsis
Showing 681-700 of 8,827 articles

Clinic-first sepsis recognition in the ICU: a proteomics-guided, parsimonious model with independent validation.

BACKGROUND: Sepsis recognition in the ICU remains variable and relies on consensus clinical criteria rather than biomarker-defined rules. Routine laboratory and physiologic data often overlap with noninfectious critical illness, obscuring early identification. We evaluated whether discovery proteomics could prioritize a concise set of routinely obtainable clinical variables, yielding a practical, ...

Mar 14 2026 41832432

Explainable machine learning for postoperative respiratory failure prediction in open-heart surgery patients - a study based on the MIMIC-IV database.

BACKGROUND: Postoperative respiratory failure (PRF) is a severe complication after open-heart surgery, associated with increased mortality and prolonged ICU stays. While machine learning (ML) models have shown promise in predicting PRF, existing models often rely on fragmented data and lack interpretability. This study aimed to develop an interpretable ML model for early prediction of PRF using da...

Mar 14 2026 41826967
[Care for uncontrolled asthma in Germany - with focus on Magdeburg and Mannheim regions].

Description of treatment and prescription patterns among asthma patients in the regions of Magdeburg (MD) and Mannheim (MA) compared nationwide.We ana...

Mar 13 2026 41825462
Bayesian networks for predicting clinical outcomes in COVID-19 patients: A retrospective study in a resource-limited setting.

BACKGROUND: The COVID-19 pandemic has highlighted the critical need for robust, interpretable predictive models to guide clinical decision-making for ...

Mar 13 2026 41824466
Genetic and clinical determinants of tacrolimus accumulation in early liver transplantation: evidence for a combined genotype-antibiotic effect.

BACKGROUND: Tacrolimus is a first-line immunosuppressant essential for preventing graft rejection after liver transplantation, but its narrow therapeu...

Mar 12 2026 41821195
FTIR spectroscopy of peripheral blood mononuclear cells and machine learning: Spectral biomarkers for bacteremia, focal bacterial, and viral infections.

The rapid and accurate differentiation of bacteremia, focal bacterial infections (FBI), and viral illnesses in febrile immunocompromised patients is a...

Mar 12 2026 41831277
Trends, Antimicrobial Resistance, and Source Attribution of Campylobacter jejuni and C. coli in Beijing: An 8-Year Molecular Surveillance Study.

OBJECTIVES: Beijing, a large urban center with complex food supply chains, faces increasing challenges from foodborne Campylobacter infections. Howeve...

Mar 12 2026 41831655
Non-polio enterovirus infection and electrophysiological changes in human iPSC-derived neural networks.

BACKGROUND: The non-polio enteroviruses (NPEV) enterovirus D68 (EV-D68) and enterovirus A71 (EV-A71) are highly prevalent and considered pathogens of ...

Mar 12 2026 41825222
Quantification, radiomics and artificial intelligence in infection imaging: Current status and future directions in nuclear medicine.

Nuclear medicine infection imaging has traditionally relied on semantic visual interpretation supported by simple semi-quantitative indices. While eff...

Mar 12 2026 41826111
[Annual progress in critical care of pulmonary medicine 2025].

This review systematically summarizes the annual research advances in the field of critical care of pulmonary, with a focus on pulmonary and critical ...

Mar 12 2026 41820043
Exploring the mechanism of polymorphonuclear neutrophils against sepsis based on immune model.

BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and remains a major global health chall...

Mar 11 2026 41814716
Modern machine learning techniques used in prediction of sepsis and bloodstream infection in burn patients: A systematic review.

INTRODUCTION: Burn patients are a group highly prone to sepsis and bloodstream infections (BSIs) due to immune dysregulation, skin barrier loss, and c...

Mar 11 2026 41946294
Toward a multiomics framework for understanding symbiotic nitrogen fixation.

Reducing dependence on synthetic nitrogen fertilizer requires biologically grounded alternatives. Symbiotic nitrogen fixation supplies fixed nitrogen ...

Mar 11 2026 41820103
Informatics for Infection Prevention and Control.

Computer informatics is integral to infection control, a role that will grow as surveillance and reporting become increasingly automated. Surveillance...

Mar 11 2026 41820135
Diagnosing orthopaedic infection by identifying neutrophils in whole histology slide images with machine learning trained on publicly available datasets.

AIMS: This study examines the ability of YOLO (You Only Look Once) 11x, a widely used and state of the art object detection model, trained on publicly...

Mar 11 2026 41808654
Culture-Free Microfluidics for Ultra-Rapid Antimicrobial Susceptibility Testing with AI in Resource-Limited Settings.

The misuse of antibiotics has accelerated the rise of antimicrobial resistance (AMR), particularly in resource-limited regions, posing a critical thre...

Mar 11 2026 41810551
AI-driven identification of a selective dual function inhibitor blocking HK2 activity and HK2-VDAC1 interaction displaying enhanced anticancer efficacy under hypoxia.

Selective inhibition of hexokinase 2 (HK2) represents a promising therapeutic strategy due to the pivotal role of HK2 in the Warburg effect, enhanceme...

Mar 10 2026 41833273
MobiRes: An integrative pipeline for resistome risk prediction through mobilome profiling.

Antimicrobial resistance (AMR) poses a significant global health challenge, with the environment serving as a crucial reservoir and conduit for resist...

Mar 10 2026 41819291
Dopamine receptors: Potential therapeutic targets for ischemia-reperfusion injury: A review.

As one of the most extensively studied neurotransmitters in the central nervous system, dopamine exerts its biological effects primarily through its r...

Mar 10 2026 41819328
Behavioral screening defines the molecular Parkinsonism-related subgroups in Drosophila.

Parkinson's disease (PD) and related familial Parkinsonism are defined by motor dysfunction, but the specific upstream molecular causes of these clini...

Mar 10 2026 41807392
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