Latest AI and machine learning research in skin cancer for healthcare professionals.
Wearable microneedles (MNs) biosensors offer significant potential for minimally invasive biomarker detection in interstitial fluid (ISF). However, suboptimal fluid collection efficiency, dermal irritation due to rigid structural components, and inadequate long-term operational stability collectively represent critical barriers to their clinical translation for early disease diagnosis. Here, we pr...
Recent innovations in skin microphysiological systems (MPSs) have gained momentum following regulatory advances such as the FDA Modernization Act 2.0 and the global shift toward alternatives to animal testing. This review highlights the development of three major technologies-3D bioprinting, skin organoids, and skin-on-a-chip-and their roles in replicating human skin physiology for research and pr...
Aging and age-related diseases are a major public health concern, driving interest in anti-aging research. While small molecules and natural compounds...
Immunotherapy, a therapeutic strategy aimed at modulating the host immune system, has undergone rapid evolution over recent decades, particularly in o...
Mushrooms are rich in structurally diverse bioactive compounds that exert potent immunomodulatory effects, making them promising candidates for next-g...
Allostery, a crucial phenomenon for comprehending protein function, interactions, and regulation, involves the transmission of perturbations induced b...
The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell-driven cancer immunotherapies. How...
In recent years, with the rapid development of medical device and biopharmaceutical technologies, the treatment model of gastric cancer surgery has be...
In the over-century-long history of colorectal tumor surgery, achieving organ function preservation has consistently been a central topic. Currently, ...
Sphincter-preserving therapy for low rectal cancer has always been a difficult and hot topic in colorectal cancer. Advanced understanding of the biolo...
Macrophage polarization between pro-inflammatory M1 and anti-inflammatory M2 phenotypes is pivotal in chronic inflammatory diseases, offering a key th...
BACKGROUND AND OBJECTIVE: Hydroxycarboxylic acid receptor 1 (HCAR1), also known as the lactate receptor, is closely associated with tumorigenesis and ...
Breast cancer continues to be a significant worldwide health concern, requiring ongoing improvements in early detection, therapeutic approaches, and c...
Uveal melanoma (UM) is among the most prevalent intraocular malignant tumors worldwide. Celastrol exhibits broad-spectrum anticancer properties; howev...
BACKGROUND: Breast cancer (BC) is the most common malignancy afflicting women worldwide, yet the role of relaxin-related genes (RLN) in BC progression...
Conventional tumor chemotherapy faces limitations including drug resistance, high toxicity, non-selectivity, and side effects. Nano-drug delivery syst...
BACKGROUND: Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents, characterized by high heterogeneity and poor prognosis. ...
Here, we utilized advanced bioinformatics approaches alongside experimental validation to identify key prognostic biomarkers and potential immune chec...
Recent advancements in cancer therapy have led to the emergence of innovative approaches that offer new hope to patients. This review provides a compr...
Dear Editor, In recent years, many individuals have turned to the Internet for health-related information, a phenomenon commonly referred to as "Dr. G...