Skin Cancer

Cross-modal mapping of cancer stem-like cell plasticity using deep learning.

Cancer stem-like cells (CSCs) play a pivotal role in driving tumor heterogeneity, therapeutic resist...

AI-assisted diagnosis of nail unit melanoma and melanonychia using a clinical deep learning model.

BACKGROUND AND OBJECTIVES: Nail unit melanoma (NUM) is a rare but potentially fatal malignancy often...

Integration of hierarchical clustering in hematologic biomarkers prediction for endocrine toxicity during immunotherapy in lung cancer patients.

Immune check-point inhibitors (ICIs) have outstandingly changed the treatment for lung cancer patien...

Single-cell and spatial transcriptomics reveal SUV39H1 as a master epigenetic driver of immunosuppressive niche and stemness in bladder cancer.

Bladder cancer (BC) exhibits profound molecular heterogeneity and a highly dynamic tumor microenviro...

Personalized cancer vaccines: bridging immune-oncology and precision medicine for advanced therapeutics.

Despite advancements in therapeutic cancer vaccines, clinical translation has been hindered by limit...

Overcoming therapeutic resistance in biliary tract cancer: from resistance mechanisms to dynamic precision oncology - a narrative review.

INTRODUCTION: Biliary tract cancer (BTC) is a biologically heterogeneous and highly aggressive malig...

Keratin gene expression signature predicts prognosis and immunotherapy efficacy in lung adenocarcinoma.

Keratins (KRTs) are intermediate filament proteins expressed in epithelial cells and serve as diagno...

Enhancing venous thromboembolism risk prediction after immunotherapy for lung cancer.

Assessing venous thromboembolism (VTE) risk after immunotherapy remains important for lung cancer ma...

Recent Advances in Immunotherapy for Breast Cancer: An Updated Review.

Immunotherapy has revolutionized the treatment landscape of breast cancer, particularly for triple-n...

Artificial intelligence (AI) uses in stereotactic radiosurgery (SRS): diagnosis with brain metastasis (BM) - A systematic review.

BACKGROUND: Brain metastases (BM) are the most common intracranial tumors in adults, and stereotacti...

Missed melanoma following skin lesion triage by an autonomous artificial intelligence system in a community setting.

Cancer Vaccine Development: Toward Artificial Intelligence-Assisted Personalized Cell Membrane Nanovaccine.

Cancer vaccines are an attractive immunotherapeutic approach, and numerous clinical trials are ongoi...

A cell-based kinetic framework enables TCR specificity prediction.

The ability to predict T-cell receptor (TCR) specificity from sequences could transform immunotherap...

Prognostic survival models for diffuse large B-cell lymphoma using statistical and machine learning approaches.

Although diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease, existing prognostic tools...

A modern review of uveal melanoma: molecular insights, clinical management, and emerging therapies.

Uveal melanoma is the most frequent primary intraocular malignancy in adults and is characterized by...

CMTM3 links inflammation-related transcriptional dysregulation to immune and therapeutic stratification in gastric cancer.

Gastric cancer (GC) shows strong biological heterogeneity and frequent disruption of inflammatory an...

A machine learning-guided epithelial plasticity score refines prognostication and immune-context stratification in muscle-invasive bladder cancer.

PURPOSE: Muscle-invasive bladder cancer (MIBC) remains biologically heterogeneous, and clinicopathol...

Pharmacogenomics in oncology: mutation-targeted therapy and biomarker integration in non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) is the most common cancer-related cause of death among all countr...

Toward a Better Paradigm for Head and Neck Cancer Treatment Applying AI (HNC-TACTIC): Protocol for an International Cohort Study of Electronic Health Records.

BACKGROUND: Head and neck squamous cell carcinomas (HNSCCs) cause considerable morbidity and mortali...

Bidirectional microbiota-cancer crosstalk: Emerging platforms for advanced diagnostics and precision therapeutics in oncology.

Cancer is among the major causes of morbidity and mortality worldwide, and current treatment methods...

Deep learning-based CD8+ T cell model for predicting prognosis and‌ targeted immunotherapy benefit in ccRCC.

Deep learning holds significant promise for improving clear cell renal cell carcinoma (ccRCC) diagno...