Latest AI and machine learning research in skin cancer for healthcare professionals.
Linking spatial transcriptomic data to clinically relevant phenotypes is essential for advancing spa...
B-cells get activated through interaction with B-cell epitopes, a specific portion of the antigen. I...
Here we are introducing CryoPhold, a modular workflow that unifies AlphaFold-based ensemble generati...
The ability to predict T cell receptor (TCR) specificity from sequence could transform immunotherapy...
T cells recognize and eliminate diseased cells by binding their T cell receptors (TCRs) to short end...
Brain metastasis (BrM) is a serious complication of advanced cancers and remains difficult to predic...
Formalin-fixed paraffin-embedded (FFPE) tissues are widely used in clinical and research settings, y...
Glioblastoma (GBM), the most aggressive primary brain tumor in adults, exhibits profound treatment r...
Understanding the spatiotemporal dynamics of T-cell clones is a critical challenge in immunology and...
T cell exhaustion limits the efficacy of cancer immunotherapies. Here, we performed genome-wide loss...
Current DNA damage repair (DDR) biomarkers employ binary classifications that fail to capture the mo...
Spatially resolved omics enable the discovery of tissue organization of biological or clinical impor...
Tumor Mutational Burden (TMB) is a widely used biomarker for selecting cancer patients for immune ch...
Accurate in silico identification of B-cell epitope residues is crucial for antibody design and stru...
Tertiary lymphoid structures (TLS) have been observed in solid tumors and have been associated with ...
Immune checkpoint blockade has emerged as a promising form of cancer therapy. However, only some pat...
Decoding cellular systems requires integrating diverse omics data, yet most models are trained from ...
Biomarker discovery for immunotherapy often requires reasoning across complex immune contexts. We pr...
Class I major histocompatibility complexes (MHCs), expressed on the surface of all nucleated cells, ...
This work introduces a modular, open-source computational pipeline for glioblastoma (GBM) vaccine de...
Stain imputation in multiplex immunofluorescence (mIF) imaging addresses the challenge of missing or...