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Smoking & Tobacco

Latest AI and machine learning research in smoking & tobacco for healthcare professionals.

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Showing 141-160 of 1,500 articles

Benchmarking Generative AI Protein Models Reveals Differences Between Structural and Sequence-based Approaches.

Recent advances in artificial intelligence have led to the development of generative models for de novo protein design. We compared 13 state-of-the-art generative protein models, assessing their ability to produce feasible, diverse, and novel protein monomers. Structural diffusion models generally create designs with higher confidence in predicted structures and more biologically plausible energy ...

Feb 15 2026 41693001

The Role of Artificial Intelligence Large Language Models in Literature Search Assistance to Evaluate the Impact of Smoking Inguinal and Ventral Hernia Repairs: A Post-Hoc Analysis.

BACKGROUND: Smoking is associated with higher complication and recurrence rates in ventral and inguinal hernia repairs, but evidence is fragmented. This study evaluated the efficacy of AI-based large language models (LLMs) for identifying literature on the impact of smoking on hernia repairs. METHODS: ChatGPT 4.0, ChatGPT 4o, Microsoft Copilot, and Google Gemini were instructed to search PubMed, E...

Feb 11 2026 41213573
Multi-omics characterization of benzo[a]pyrene toxicity networks identifies SERPINE1 and STK3 as prognostic biomarkers and therapeutic targets in head and neck squamous cell carcinoma.

Benzo[a]pyrene (BaP), a ubiquitous environmental carcinogen predominantly found in tobacco smoke and air pollution, plays a pivotal role in head and n...

Feb 11 2026 41670688
Primary infliximab failure in pediatric colonic inflammatory bowel disease: Development of a proteomics predictive model using a prospective Canadian cohort.

BACKGROUND: We aimed to build a serum proteomics-based model to predict primary nonresponse (PNR) to infliximab (IFX) in pediatric colonic inflammator...

Feb 11 2026 41671043
Integrating environmental factors and genetic variants in machine learning to assess occupational noise impact on health.

Noise-induced hearing loss (NIHL) is a complex disorder arising from the interplay between noise, as well as contributions from other environmental an...

Feb 10 2026 41671953
Characterising 'Spree Bar': an examination of the popularity, marketing and composition of a vaping device with a nicotine analogue across multiple data streams.

BACKGROUND: Spree Bar, a line of e-cigarette devices introduced in 2023, leverages 6-methylnicotine (6-MN) as its primary ingredient and is available ...

Feb 10 2026 41667265
Development of an explainable machine learning model for predicting depression in adults with type 2 diabetes mellitus: A cross-sectional SHAP-based analysis of NHANES 2009-2023.

Depression (DEP) is a common yet underdiagnosed comorbidity in adults with type 2 diabetes mellitus (T2DM), worsening glycemic control and increasing ...

Feb 6 2026 41650107
Developing an Interpretable Machine Learning Framework to Predict and Analyse Early Childhood Caries in Children Aged 2 to 6 Years: A Single-centre Observational Study.

BACKGROUND: Early childhood caries (ECC) is a prevalent global oral health condition, exerting profound adverse effects on children's oral health, gen...

Feb 5 2026 41650830
A Novel Risk Calculator for Nonhome Discharge after Lower Extremity Bypass.

BACKGROUND: Nonhome discharge (NHD) after lower extremity bypass is associated with discharge delays, increased postdischarge complications, and reduc...

Feb 4 2026 41651166
Treating those not ready to quit smoking: Doing harm while trying to help?

INTRODUCTION: Motivation-phase smoking treatment can increase treatment reach and abstinence in persons unmotivated to quit smoking. However, Motivati...

Feb 3 2026 41650518
Filling the Gaps in Health Data: Using a Machine Learning Approach to Augment Partially Observed Variables Such as Smoking in Claims Data.

PURPOSE: Missing information is common in real-world claims data, particularly on behavioral confounders, for example, smoking. Often one category of ...

Feb 1 2026 41612631
From non-specific biomarker to targeted action: transdiagnostic and sex-specific drivers of high-CRP status in severe mental illness across the FondaMental Advanced Centers of Expertise (FACE) cohorts.

BACKGROUND AND OBJECTIVES: Low-grade systemic inflammation contributes to the pathophysiology of severe mental illness (SMI) in a substantial subset o...

Jan 30 2026 41621630
Integrative transcriptomics, machine learning, and molecular docking reveal that nicotine exacerbates ischemic stroke: TLR4-dependent activation of NLRP3/caspase-1/GSDMD-mediated microglial pyroptosis.

OBJECTIVE: This study aimed to clarify the molecular mechanisms through which nicotine (Nic) aggravates ischemic stroke (IS), with an emphasis on infl...

Jan 29 2026 41609381
The Development and Use of AI Chatbots for Health Behavior Change: Scoping Review.

BACKGROUND: Artificial intelligence (AI) chatbots are technologies that facilitate human-computer interaction through communication in a natural langu...

Jan 28 2026 41604667
Vaping Goes Viral: The Role of Commercial E-Cigarette Tweets in Youth E-Cigarette Use Susceptibility.

INTRODUCTION: Social media (SM) are major marketing platforms for e-cigarette product promotion, particularly among youth. While prior studies have es...

Jan 22 2026 41568776
Development and Validation of a Urinary Exosomal miRNA Diagnostic Panel for Early Detection of Esophageal Cancer.

Esophageal squamous cell carcinoma (ESCC) remains a leading cause of cancer-related mortality, with early detection being challenging. Although endosc...

Jan 19 2026 41553857
Deep learning-guided engineering of pectinase for enhanced catalytic performance in tobacco processing.

Deep learning is revolutionizing enzyme engineering through efficient residue redesign. Leveraging deep learning for enzyme engineering, we redesigned...

Jan 17 2026 41554444
Predictors of past 30-day vaping abstinence among young e-cigarette users: Machine learning analysis of a longitudinal cohort.

INTRODUCTION: Our existing knowledge on factors influencing vaping abstinence are still limited. The objective of this study was to build a machine le...

Jan 14 2026 41548499
Automated Lymph Node and Extranodal Extension Assessment Improves Risk Stratification in Oropharyngeal Carcinoma.

PURPOSE: Extranodal extension (ENE) is a biomarker in oropharyngeal carcinoma (OPC) but can only be diagnosed via surgical pathology. We applied an au...

Dec 23 2025 41435207
Targeting High-Risk Populations for Abdominal Aortic Aneurysm Screening: A Sex-Stratified Analysis in an Ethnicity Diverse Cohort Incorporating Machine Learning Tools.

BACKGROUND: Abdominal aortic aneurysm (AAA) is usually asymptomatic, but rupture carries up to 90% mortality. Ultrasound screening reduces rupture-rel...

Dec 18 2025 41421582
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