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Stem Cell Research

Latest AI and machine learning research in stem cell research for healthcare professionals.

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A randomized clinical trial reveals effects of mindfulness and slow breathing on plasma amyloid beta levels

Prior research suggests that meditation may slow brain aging and reduce the risk of Alzheimer’s disease (AD). However, we lack research systematically examining what aspect(s) of meditation may drive such benefits. In particular, it is unknown how breathing patterns during meditation might influence health outcomes associated with AD. In this study, we examined whether two types of mindfulness med...

Artificial Intelligence Models for Predicting Molecular Pathway Activity in Spinal Cord Injury: A Systematic Review

Spinal cord injury (SCI) remains a devastating neurological condition with high global incidence and minimal curative options. The pathobiology is multifactorial, encompassing acute mechanical insult, sustained neuroinflammation, oxidative stress, mitochondrial dysfunction, and glial scarring. Molecular signaling pathways orchestrate these responses, yet their clinical exploitation has been hinder...

Privacy-Preserving Retrieval-Augmented Generation on Local Devices for Regenerative Medicine Applications

Retrieval-augmented generation (RAG) has emerged as a promising approach to improve the factual consistency and domain-specific accuracy of large lang...

Automatic Sleep Staging from CPAP Airflow using a Dual Fusion Multi-Period Convolutional Neural Network

Background: Continuous Positive Airway Pressure (CPAP) therapy is the standard treatment for obstructive sleep apnea-hypopnea syndrome, yet its use as...

Personalized Fluid Management in Patients with Sepsis and AKI: A Casual Machine Learning Approach

Intravenous (IV) fluids are cornerstone for management of acute kidney injury (AKI) after sepsis but can cause fluid overload. Restrictive fluid strat...

Understanding the Relationship Between Germ Layer Origin and Cancer Therapy Response: A Systematic Review

Cancer therapeutic response patterns may be fundamentally influenced by embryonic germ layer origin. Emerging evidence suggests mesoderm-derived malig...

A Glioma Stem Cell–Associated Transcriptomic Program Predicts Survival Across Adult and Pediatric High-Grade Gliomas

High-grade gliomas (HGGs), including adult glioblastoma (GBM) and pediatric diffuse intrinsic pontine gliomas (DIPGs), are sustained by glioma stem ce...

Leveraging simulation to provide a practical framework for assessing the novel scope of risk of LLMs in healthcare

Large language models (LLMs) are rapidly entering clinical care, yet their definitionally probabilistic outputs have delivered a variety of grossly un...

Radiologic, Pathologic, and Deep Learning Predictors of Response to Immune Checkpoint Blockade in Renal Cell Carcinoma Patients Undergoing Post-Treatment Nephrectomy

Response assessment of primary kidney tumors in the consolidation cytoreductive and neoadjuvant settings offers a unique opportunity to inform postope...

PREFER-IT: A transdisciplinary co-created framework to realise inclusive medical AI

Artificial intelligence (AI) in healthcare holds transformative potential but risks exacerbating existing health disparities if inclusivity is not exp...

Unintended Pregnancy and Preterm Birth in the United States: Causal Inference and Risk Prediction Using National Survey of Family Growth Data

Unintended pregnancy remains common in high income countries and has been linked to poorer maternal and neonatal outcomes. Whether pregnancy intention...

Circulating microglia-derived extracellular vesicles predict recovery after rehabilitation in stroke survivors

Timely intensive rehabilitation is crucial to contrast the negative escalation of events that follow a stroke injury, to promote tissue regeneration, ...

Medication-Stratified Analysis of LDL-C Equation Miscalibration in Diabetes: Evidence from the All of Us Research Program and a Medication-Agnostic Machine-Learning Correction

Standard LDL-C equations were derived in cohorts largely untreated with modern combination diabetes therapies. With medication-treated patients compri...

Comparison of Time- and Frequency-Domain Methods for Assessing Brain Compliance in Brain-Injured Patients Monitored With Intraparenchymal Intracranial Pressure Sensors

Intracranial pressure (ICP) monitoring is commonly used in neuro-intensive care, but its utility may be limited by a suboptimal use. The brain pressur...

LLM-Based Classification of Case Report Abstracts: A Pilot Study on Interactions between Radiotherapy and Systemic Therapies

The growing volume of biomedical literature, especially in oncology, necessitates automated tools for extracting clinically relevant information. Larg...

Predicting the efficacy of Recombinant Human Thrombopoietin in Treating Cancer Therapy-Related Thrombocytopenia:based on stacking ensemble methods

The project aimed to develop a data-driven approach for predicting platelet recovery in cancer treatment–induced thrombocytopenia (CTIT) patients rece...

Tracking funding disparities in global health aid with machine learning

Reducing the global burden of disease is crucial for improving health outcomes worldwide. However, misalignment between health aid and country-level d...

Research at the Intersection of Traditional, Complementary, and Integrative Medicine and Artificial Intelligence: A Bibliometric Analysis

Traditional, complementary, and integrative medicine (TCIM) describes a broad collection of medical interventions, practices, and belief systems that ...

Adapting Clinical Ethics Consultations to Address Ethical Issues of Artificial Intelligence.

AbstractAs artificial intelligence (AI) becomes increasingly incorporated into the workflow of clinical practice, it will raise numerous ethical issue...

Jan 1 2025 40397973
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