Latest AI and machine learning research in stem cell research for healthcare professionals.
Gene delivery for neurodegenerative cerebral disorders faces formidable structural and practical challenges. The blood-brain, blood- cerebrospinal fluid (CSF), and arachnoid barriers tightly regulate molecular traffic, restrict paracellular diffusion, and actively clear xenobiotics, limiting brain penetration and retention of large molecules and nucleic acid therapeutics. Additional barriers inclu...
Over the past two decades, photonic sensing has transitioned from laboratory concepts to clinically relevant tools for disease detection and treatment guidance, driven by the convergence of nanotechnology, artificial intelligence (AI), and advanced fabrication. Unlike recent reviews that focus narrowly on individual technologies, this Perspective synthesizes advances across silicon photonics, nano...
Health systems are under increasing pressure as chronic disease becomes the dominant burden of care. Addressing this requires earlier detection and pr...
INTRODUCTION: Early childhood development (ECD) interventions support children aged 0-5 years, including those typically developing, at risk of delays...
INTRODUCTION: Any tool that can reduce the administrative burden on healthcare providers while preserving safe, accountable and high-quality medical d...
BACKGROUND: Aging is marked by changes in DNA methylation (DNAm) including an increase in randomness or entropy in the epigenome. Here, we computed ep...
Neoadjuvant dual HER2 blockade with trastuzumab and pertuzumab plus chemotherapy represents the current standard-of-care for HER2-positive breast canc...
Quantifying three-dimensional preclinical myocardial deformation in vivo currently remains a challenging task, as non-invasive cardiac imaging methods...
Traumatic brain injury (TBI) is a leading cause of persistent cognitive, motor, and neuropsychiatric impairment, arising from both the initial mechani...
T cell receptors (TCRs) are central to adaptive immunity, yet their vast sequence and structural diversity present a significant challenge to fully un...
INTRODUCTION: The global prevalence of heart failure continues to increase, particularly in ageing populations. Many older patients receiving home-bas...
BACKGROUND: National Institutes of Health (NIH) investment in artificial intelligence (AI) within surgical specialties is rapidly expanding, yet wheth...
Gastrointestinal endoscopy has undergone rapid technological evolution, yet many clinician innovators remain unfamiliar with the pathways required to ...
BACKGROUND: Response evaluation in pleural mesothelioma is challenging because its crescent growth pattern is poorly captured by diameter-based criter...
OBJECTIVE: Phase gating is a critical technique to mitigate tumor motion during radiotherapy, particularly in spot-scanned particle therapy (SSPT) whe...
Therapy-induced senescence (TIS) in cancer cells can be triggered by radiotherapy, chemotherapy, and certain targeted therapeutics. Here, we demonstra...
Accurate prediction of disease-free survival (DFS) is essential for tailoring adjuvant regimens and improving clinical outcomes in early-stage breast ...
BACKGROUND: Digital health offers opportunities for safe, equitable, and accessible care, and its integration into respiratory care is a strategic pri...
BACKGROUND: Nasopharyngeal carcinoma requires reliable diagnostic biomarkers due to its occult location and poor outcomes. METHODS: This study analyze...
Increasing evidence has highlighted the biological significance of 5-methylcytosine (5mC) DNA modification in regulating tumorigenesis and cancer prog...