Stem Cell Research

Artificial intelligence and machine learning in robotic, teleoperated, and remote surgery: a bibliometric and knowledge mapping analysis (2015-2025).

Artificial intelligence (AI) and machine learning (ML) technologies are rapidly transforming telesurgery by enhancing robotic-assisted surgical systems, remote surgical communication, image-guided interventions, and intelligent decision-making. The integration of AI-driven algorithms with telesurgical platforms has accelerated research activity across medicine, robotics, engineering, and computer ...

Endometriosis and the mental health burden: a registry-based study of redeemed prescriptions and psychiatric hospital contacts before and after diagnosis of endometriosis.

STUDY QUESTION: Do women with endometriosis have a higher use of antidepressants and anxiolytics, and more frequent psychiatric hospital contacts due to depression or anxiety, before and after receiving their endometriosis diagnosis, compared with women without endometriosis? SUMMARY ANSWER: Women with an endometriosis diagnosis redeemed more prescriptions for antidepressants and anxiolytics and h...

Multi-omics body-fluid biomarkers in immunoglobulin a nephropathy: Analytical Validation, standardization, and clinical chemistry translation of diagnostic and prognostic Analytes.

IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide. Although optimized supportive therapy is administered to these pati...

Mitochondrial Metabolic Biomarkers in Periodontitis: Discovery and Clinical Validation.

INTRODUCTION AND AIMS: Mitochondrial metabolic dysregulation is associated with periodontitis (PD); however, related biomarkers remain unclear. In thi...

Data After Death: Post-Mortem Ethics of Burn Patient Records and Images.

Burn care frequently relies on extensive documentation, including graphic photographic images and detailed clinical records. While these materials are...

A Review of the Australian MRI Linac Program: From Pie in the Sky to Research Milestone.

The Australian Magnetic Resonance Imaging (MRI) Linear Accelerator program (MRI linac) was a major research project that aimed to build and test a uni...

Manual therapy promotes prefrontal neural efficiency in chronic non-specific neck pain: An fNIRS-Based randomized controlled trial.

BACKGROUND: Chronic non-specific neck pain (CNP) involves central sensitization and maladaptive cortical reorganization. The central neurophysiologica...

Perceptions of challenges in clinical pediatric research: a survey of Italian pediatricians.

BACKGROUND: Clinical research is essential for advancing pediatric care, yet pediatricians often face unique structural, organizational, and methodolo...

Expanding the ethics horizon: integrating African canons for inclusive research ethics in Africa.

BACKGROUND AND INTRODUCTION: Society 5.0 envisions a future where technology and humanity integrate to address societal concerns. In an era marked by ...

Machine Learning-Optimized Single-Atom Catalysts Enable Microenvironment-Adaptive Chemodynamic-Bioorthogonal Cancer Therapy.

Chemodynamic therapy (CDT), which harnesses endogenous chemical energy within the tumor microenvironment (TME), has shown high potential for precise c...

Breaking Barriers in Student Mental Health Care With AI-Enhanced Group Cognitive Behavioral Therapy: Pilot Feasibility Study.

BACKGROUND: University students experience elevated psychological distress, with limited access to mental health services. While cognitive behavioral ...

Multifunctional Bioengineered Scaffolds and Adjunct Therapeutic Strategies for Diabetic Foot Ulcers.

Diabetic foot ulcers (DFUs) are chronic, non-healing wounds that affect up to 34% of diabetic patients. DFUs are complicated by infection in nearly 60...

An exploratory multimodal pipeline for recurrence prediction in CRC with XELOX therapy.

Colorectal cancer(CRC) recurrence remains a challenge despite curative surgery and adjuvant therapy. Integrating clinicopathological and liquid biopsy...

Artificial Intelligence in Neuropathic Pain: From Mechanisms to Neuromodulation and Regenerative Strategies.

PURPOSE OF REVIEW: Neuropathic pain remains challenging due to its heterogeneous mechanisms and variable treatment response. This narrative review eva...

HS-QFNet: Deep learning-enhanced hyperspectral fluorescence correction for accurate in vivo photosensitizer concentration quantification.

Accurate quantification of photosensitizer concentration is essential for effective fluorescence-guided surgery and personalized photodynamic therapy,...

Construction and validation of a preimplantation kinship identification model using ultra-low-depth whole genome sequencing.

Errors during in vitro fertilization (IVF) workflows pose significant risks; yet, existing quality control measures remain insufficient. Herein, we de...

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI-Oriented Perspective.

Cryopreservation is the storage of biological materials like cells, tissues, or even organs at cryogenic temperatures. This technology is a key enable...

AI-Guided Patient-Derived Endothelial Modeling Identifies a Reversible Moyamoya-Specific miRNA Deficiency Corrected by Stem Cell-Extracellular Vesicles.

Moyamoya disease (MMD) is a progressive cerebrovascular disorder characterized by abnormal vascular remodeling and impaired angiogenesis. We profiled ...

Analysis of blastocyst morphokinetics assessed by time-lapse technology and its correlation with human IVF treatment outcome.

Human embryo selection in in vitro fertilisation (IVF) treatments is traditionally based on evaluating cell number, morphology, and fragmentation to s...

IgG4-related disease has a specific intestinal microbiota signature.

BACKGROUND: While the intestinal microbiome has been implicated in Immunoglobulin-4 related disease (IgG4-RD), it remains poorly characterised. Theref...