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Stem Cell Research

Latest AI and machine learning research in stem cell research for healthcare professionals.

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Mapping 3Rs and NAM research and innovation projects funded through European framework programmes since 2007.

The development of new approach methodologies (NAMs) is increasingly enabling the replacement and reduction of animal use in research, complementing the ethical framework provided by the 3Rs (replacement, refinement, and reduction) of animal research. The European Commission has supported these approaches by embedding 3R requirements in policy frameworks and providing dedicated funding for 3Rs/NAM...

Apr 15 2026 41984093

Development of a Contextualized, Research-Based Flemish Assessment Framework for Digital Care, Assistance, and Support: Delphi Study.

BACKGROUND: The rapid evolution of digital technologies has transformed health, mental health, and social care, offering new modalities of digital care, assistance, and support through web-based platforms, mobile apps, extended reality, wearables, and artificial intelligence systems. Despite this proliferation, there is little consensus on what constitutes "high-quality" digital care. Challenges p...

Apr 15 2026 41984529
Cytoplasmic lattices are megadalton storage complexes in mammalian oocytes.

Mammalian oocytes store proteins for embryonic development on abundant structures known as cytoplasmic lattices (CPLs)1; however, the mechanisms by wh...

Apr 15 2026 41986725
[Comparative observation of analgesic efficacy between liposomal bupivacaine and "cocktail" therapy following artificial intelligence-assisted direct anterior approach total hip arthroplasty: A prospective randomized controlled study].

OBJECTIVE: To compare the analgesic efficacy and safety of liposomal bupivacaine (LB) versus ropivacaine for surgical incision local anesthesia after ...

Apr 15 2026 41981425
The promise of injectable hydrogels in dental bone regeneration.

Injectable hydrogels are considered to be a minimally invasive approach for the regeneration of the dental bone, providing a number of benefits over t...

Apr 14 2026 41986226
Prediction of Relapse Using Digital Technology in People in Recovery From Substance Use Disorders: Early Economic Evaluation With a Case Study of the Subreal App.

BACKGROUND: Many people relapse after achieving abstinence in substance use disorders. Health care providers may scan the horizon for new technologies...

Apr 14 2026 41979981
Design of Single-Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single-Cell RNA Sequencing and Machine Learning.

Patients with diabetes mellitus-induced erectile dysfunction (DMED) usually suffer more severe symptoms, and efficacy of the first-line therapy is lim...

Apr 14 2026 41980199
Hi-Compass: a depth-aware deep learning framework for predicting cell-type-specific 3D genome organization from single-cell to spatial resolution.

Three-dimensional genome organization controls cell-type-specific gene expression through chromatin interactions, yet systematic analysis across diver...

Apr 14 2026 41980945
Mapping AI startup investment and innovation in healthcare using a five-tier AI systems complexity framework.

Artificial Intelligence (AI) is reshaping healthcare through advances in diagnostics, treatment, and operations, yet the startup ecosystem driving thi...

Apr 14 2026 41974803
Integrating Gait Analysis and AI Into Knee Osteoarthritis Care: Protocol for a 3-Phase Participatory Qualitative Study.

BACKGROUND: Knee osteoarthritis (OA) leads to pain, disability, and reduced quality of life. For advanced stages, knee arthroplasty surgery is the sta...

Apr 13 2026 41973876
Modeling Collective Cell Migration in a Data-Rich Age: Challenges and Opportunities for Data-Driven Modeling.

Mathematical modeling has a long history in the context of collective cell migration, with applications throughout development, disease, and regenerat...

Apr 13 2026 41974539
Bridging Trials and Real Life in Fixed-Duration BTKi-Venetoclax for CLL: A Delphi-Enhanced Synthesis Incorporating Artificial Intelligence (AI) Benchmarks.

BACKGROUND: Optimal patient selection for the most effective BTK inhibitor (BTKi) partner of venetoclax in fixed-duration (FD) BTKi-venetoclax regimen...

Apr 13 2026 41974594
Fair enough? How developers and clinicians justify who receives physical assistive robotics in rehabilitation.

BACKGROUND: Physical assistive robots are increasingly promoted in rehabilitation. However, it remains unclear how and for whom, physical assistive ro...

Apr 12 2026 41990551
A multiparameter model (OsteoSC-M3) for early detection and risk stratification of osteoporosis in women: a multicentre cohort study in China.

BACKGROUND: Osteoporosis is a major global health issue, but current early screening tools lack accuracy, and the gold-standard diagnostic method, dua...

Apr 11 2026 42016607
High-throughput strategy for targeting MDM2 in uveal melanoma to reverse radiation therapy resistance.

Uveal melanoma (UM) presents a formidable clinical challenge due to its marked resistance to radiotherapy. In this study, an integrative strategy comb...

Apr 11 2026 41965789
Deep learning on genome-wide association studies to predict the patient-specific risk of radiation-induced erectile dysfunction.

OBJECTIVE: Radiation-induced erectile dysfunction (RIED) is a frequent, unpredictable complication following radiotherapy for prostate cancer. We hypo...

Apr 10 2026 41967608
Neuroplasticity after Stroke: Adaptive and Maladaptive Mechanisms in Evidence-Based Rehabilitation.

BACKGROUND AND PURPOSE: Ischemic stroke remains a leading cause of long-term disability and persistent motor deficits. While neuroplasticity drives po...

Apr 10 2026 41967694
Subphenogroups of acute heart failure with preserved ejection fraction: comprehensive proteomics and pathway analysis.

BACKGROUND: Heterogeneity of heart failure with preserved ejection fraction (HFpEF) results in significant challenges for treatment development. Ident...

Apr 10 2026 40750341
A machine-learning-based tool for stroke risk prediction in blunt cerebrovascular injury: development and preliminary evaluation.

PURPOSE: Stroke risk correlates with the Biffl grading system in blunt cerebrovascular injury (BCVI). Although anti-thrombotic therapy is the mainstay...

Apr 10 2026 41961261
Facilitators and barriers of research engagement in a large teaching hospital in the Netherlands: a narrative reflection.

BACKGROUND: Healthcare organisations are facing major challenges, including workforce shortages, rising costs, and an aging population. Research engag...

Apr 10 2026 41963960
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