Public Health & Policy

Stem Cell Research

Latest AI and machine learning research in stem cell research for healthcare professionals.

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TAPSeg: An Open-Source Deep Learning Tool for Instance-Level Tooth and Pulp Segmentation in CBCT.

OBJECTIVES: To develop an open-source one-tap CBCT automatic segmentation tool based on deep learning to perform integrated segmentation and reconstruction of teeth and pulp in the 3D Slicer software and verify its generalization ability on multiple datasets. METHODS: Three datasets were used for model training and evaluation. Tooth segmentation employed a three-stage V-Net collaborative framework...

Mar 20 2026 41865812

AI-assisted tumor board decision-making in pancreatic oncology.

BACKGROUND: Pancreatic cancer requires nuanced, multidisciplinary treatment planning typically conducted within tumor boards. While Large Language Models (LLMs) have shown capabilities in medical reasoning, their ability to approximate complex, integrative decision-making in oncology remains underexplored. METHODS: This study evaluated the performance of LLaMA 3.3 (70b) in predicting tumor board d...

Mar 20 2026 41862918
Contrasting roles of PD-L1 expression in tumor and stroma: Biological and prognostic implications in esophageal squamous cell carcinoma.

Programmed death-ligand 1 (PD-L1) plays a central role in immune regulation in esophageal squamous cell carcinoma (ESCC) and has been widely used as a...

Mar 20 2026 41859819
Dense and distributed neuropeptide network in the nerve net of Hydra vulgaris.

Neuroscience has long emphasized synaptic transmission and physical wiring as the substrate of brain function and behavior. However, an additional lay...

Mar 20 2026 41860945
Atypical Ductular Reactions Are a Distinct Regenerative Phenomenon in Hepatocellular Carcinoma (HCC) Patients after Transarterial Chemoembolization.

Transarterial chemoembolization (TACE) is increasingly used in patients with hepatocellular carcinoma (HCC), the most frequent primary liver tumor. At...

Mar 19 2026 41864479
Outcomes and Predictive Modeling in Helmet Therapy for Plagiocephaly.

OBJECTIVE: To develop and evaluate a machine learning model to forecast treatment-related changes in cranial vault asymmetry index (CVAI) and cranial ...

Mar 19 2026 41864497
Deep learning-based early screening for porcine embryos with different developmental potential.

The developmental potential of in vitro embryos is a critical determinant of porcine artificial reproduction technology (ART) efficiency. However, the...

Mar 19 2026 41865699
Estimating major pathological response in non-small cell lung cancer patients with post-neoadjuvant therapy using MMT-net.

Neoadjuvant therapy (NAT) has demonstrated considerable effectiveness in treating locally advanced non-small cell lung cancer (NSCLC). Major pathologi...

Mar 19 2026 41857185
5-Hydroxymethylcytosine profiles in circulating cell-free DNA serve as potential biomarkers for diagnosis and classification of adenomyosis.

BACKGROUND: Adenomyosis diagnosis and classification relies primarily on magnetic resonance imaging or pathological examination. Liquid biopsy has bee...

Mar 19 2026 41861514
Synergistic Effect of a Combined 10-MDP/γ-MPTS Primer on Glass-Ceramic Bonding: A Multimodal Study.

INTRODUCTION AND AIMS: This study investigated the synergistic effect of combining 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) and γ-methacr...

Mar 19 2026 41861583
Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair.

Bioprinting, first proposed in the 1980s for ex vivo tissue fabrication, has evolved into a cornerstone of regenerative medicine. Conventional approac...

Mar 19 2026 41852289
Public Engagement Strategies in Digital Health Ethics: Protocol for a Scoping Review.

BACKGROUND: The ethical, legal, and social issues accompanying the latest advancements in digital health technologies highlight the need to involve th...

Mar 19 2026 41855498
Hypoxia-related and immune phenotype-related fusion model for non-invasive prognostication of hepatocellular carcinoma treated by TACE: a multicentre study.

BACKGROUND: Survival outcomes after transarterial chemoembolisation (TACE) vary in hepatocellular carcinoma (HCC) patients, and existing prognostic sc...

Mar 19 2026 41856522
Thymic health consequences in adults.

The thymus is essential for establishing T cell diversity early in life, but undergoes profound involution with age and has therefore traditionally be...

Mar 18 2026 41851466
Proteomics in tissue regeneration: insights into protein alterations and post-translational modifications during healing.

Tissue regeneration is a complex, multi-phase process orchestrated by dynamic changes in protein expression and post-translational modifications (PTMs...

Mar 18 2026 41848587
AI-Derived Electronic Tumor Marker For Cancer Antigen 19-9 Nonproducers With Pancreatic Ductal Adenocarcinoma.

IMPORTANCE: Cancer antigen 19-9 (CA19-9) is used to assess treatment response among patients with pancreatic ductal adenocarcinoma (PDAC); however, ne...

Mar 18 2026 41848749
Ethics tools for strengthening ethics review: A scoping Review.

BACKGROUND: Ethics review of research and innovation activities face growing challenges due to rapid scientific and technological advances, interdisci...

Mar 17 2026 41845876
Tumor organoids on-a-chip and the role of AI in predictive oncology and personalized cancer medicine.

The drug development process in cancer faces significant challenges due to high failure rates in translational studies despite promisingin vitroresult...

Mar 17 2026 41512327
Molecular and Pharmacogenetic Marker Evaluation in Relation to the Toxicity and Clinical Response of Acute Lymphoblastic Leukemia Treatment in Indian Children (MPGx-INDALL): Protocol for a Prospective Observational Cohort Study.

BACKGROUND: Understanding interindividual variability in treatment response and toxicity is essential for optimizing outcomes in pediatric acute lymph...

Mar 17 2026 41843828
You Can't Sit on the Lid of Progress: Human Dignity, Ethical Leadership, and the Future of Professional Nursing.

Nursing stands at a critical inflection point-shaped by global complexity, rapid technological change, and the enduring moral commitment to human cari...

Mar 17 2026 41875482
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