Latest AI and machine learning research in stem cell research for healthcare professionals.
Recent clinical trial data show curative potential of cell therapy for diabetes, however the cells required are a bottleneck. Cell differentiation exhibits substantial variability, even among clones of stem cells generated from the same patient. Human experts struggle to see the difference between highly- and lowly-efficient cell clones early. We therefore propose an image-based deep learning mode...
Chimeric antigen receptor (CAR) T-cell therapy holds great promise for patients with cancer, and the identification of predictive biomarkers is crucial in finding new ways to guide therapy. Major challenges to the application of informatics and machine learning in CAR T-cell therapy include limited sample sizes and non-uniformity in data generation across cancer indications and trials. Here we too...
UNLABELLED: The gut virome is an emerging but underexplored component of the human microbiota, especially in pediatric Crohn's disease (CD). This stud...
Cytokine release syndrome (CRS) greatly impacts survival in patients who undergo chimeric antigen receptor (CAR)-T cell therapy, and the identificatio...
BACKGROUND: Type 2 diabetes mellitus (T2D) is a rapidly growing global health concern requiring innovative treatment methods. Ozempic (semaglutide), a...
Despite significant progress in porcine in vitro embryo production (IVP), major challenges persist, particularly regarding the biological quality and ...
INTRODUCTION: Total tumor number (TTN) and total tumor volume (TTV) reflect tumor burden and have been linked to outcomes in metastatic colorectal can...
Emphysema, a primary component of chronic obstructive pulmonary disease (COPD), causes progressive dyspnea through the destruction of alveolar membran...
BACKGROUND: With the emergence of voice as a digital biomarker for various health conditions over the last decade, healthcare institutions are explori...
Pulmonary fibrosis (PF) is a progressive and fatal interstitial lung disease characterized by irreversible lung scarring and frequently associated wit...
BACKGROUND: Gallbladder cancer (GBC) diagnosis is challenging due to overlapping imaging features. We developed and validated a multiple instance lear...
Air pollution is a major cardiovascular risk factor, with particulate matter (PM) posing significant threats. The Po Valley remains among Europe's mos...
The aim of the study was to evaluate the concordance between radiological imaging modalities and pathological findings and to test whether neoadjuvant...
Corporate AI ethics statements are being increasingly integrated into sustainability communication to showcase responsible AI performance as part of b...
Osteoporotic bone defects (OBD) present a major clinical challenge, largely due to a pathological bone microenvironment that severely compromises rege...
Preimplantation genetic testing (PGT) is a critical tool in reproductive medicine for selecting genetically healthy embryos, thereby reducing the risk...
BACKGROUND: Accurate detection of lymph node metastasis is crucial for precise tumour staging and treatment planning. Conventional pathological examin...
INTRODUCTION: As artificial intelligence (AI) becomes increasingly embedded in clinical workflows, clinicians encounter ethical challenges that tradit...
Smart farming technologies significantly enhance medicinal plant cultivation by improving yield, quality, and sustainability, while addressing traditi...
Chimeric antigen receptor (CAR) T-cell therapy has transformed the management of hematologic malignancies, achieving high remission rates in relapsed ...