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Stem Cell Research

Latest AI and machine learning research in stem cell research for healthcare professionals.

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Evaluation of Hepatic Progenitor and Hepatocyte-Like Cell Differentiation Using Machine Learning Analysis-Assisted Surface-Enhanced Raman Spectroscopy.

Technology has been developed to monitor the differentiation process of human mesenchymal stem cells (hMSCs) into hepatocyte-like cells (HLCs) and hepatic progenitor cells (HPCs). These cell lineages, differentiated from MSCs, are ethically unproblematic and are gaining attention as promising cell-based therapies for treating various liver injuries. High-sensitivity, label-free, real-time monitori...

May 7 2025 40337141

Invited Article: Al guided Dual Antiplatelet Therapy and Anticoagulation.

Artificial intelligence (AI) has emerged as a transformative tool in healthcare through data analysis, pattern recognition and predictive modeling capabilities. AI-driven approaches have the potential to positively transform patient care through personalized treatment regimens comprising antiplatelet and anticoagulant therapy. This review explores the integration of AI in guiding antithrombotic th...

May 6 2025 40327556
Orexin Restoration in Narcolepsy: Breakthroughs in Cellular Therapy.

Narcolepsy is a chronic neurodegenerative disorder defined by the selective loss of orexin-producing neurons in the lateral hypothalamus, leading to e...

May 5 2025 40325840
Application of multivalent aptamers in tumor diagnosis, analysis and therapy (Review).

Cancer remains one of the leading causes of mortality worldwide, making early diagnosis and precise treatment crucial for enhancing patient survival r...

May 2 2025 40370647
Optimizing stroke lesion segmentation: A dual-approach using Gaussian mixture models and nnU-Net.

Machine learning-based stroke lesion segmentation models are widely used in biomedical imaging, but their ability to detect treatment effects remains ...

May 2 2025 40318493
Forecasting optimal treatments in relapsed/refractory mature T- and NK-cell lymphomas: A global PETAL Consortium study.

There is no standard of care in relapsed/refractory T-cell/natural killer-cell lymphomas. Patients often cycle through cytotoxic chemotherapy (CC), ep...

May 1 2025 40310502
Characterization of Effective Half-Life for Instant Single-Time-Point Dosimetry Using Machine Learning.

Single-time-point (STP) image-based dosimetry offers a more convenient approach for clinical practice in radiopharmaceutical therapy (RPT) compared wi...

May 1 2025 40113223
Organoid-Guided Precision Medicine: From Bench to Bedside.

Organoid technology, as an emerging field within biotechnology, has demonstrated transformative potential in advancing precision medicine. This review...

May 1 2025 40321594
Flexor Synergy Assessment and Therapy for Persons With Stroke Using the ULIX Low Impedance Robot.

The flexor synergy after stroke results in involuntary activation of distal muscles when lifting the shoulder against gravity. This contributes to imp...

Apr 29 2025 40249696
Potential for near-term AI risks to evolve into existential threats in healthcare.

The recent emergence of foundation model-based chatbots, such as ChatGPT (OpenAI, San Francisco, CA, USA), has showcased remarkable language mastery a...

Apr 27 2025 40288807
Therapeutic potential of enzymes, neurosteroids, and synthetic steroids in neurodegenerative disorders: A critical review.

Neurodegenerative disorders present a significant challenge to healthcare systems, mainly due to the limited availability of effective treatment optio...

Apr 25 2025 40288591
Timing of kidney replacement therapy in critically ill patients: A call to shift the paradigm in the era of artificial intelligence.

Acute kidney injury (AKI) is a common condition in intensive care units (ICUs) and is associated with high mortality rates, particularly when kidney r...

Apr 24 2025 40275676
Single Joint Hybrid Assistive Limb (HAL-SJ) robotic exoskeleton therapy in improving functional outcomes among workers with wrist fractures: Study protocol for a randomized controlled trial.

INTRODUCTION: Robotic technologies have been developed for motor rehabilitation and such robots have shown favourable results when compared with equiv...

Apr 24 2025 40273196
First Clinical Implementation of Step-and-Shoot Proton Arc Therapy for Head and Neck Cancer Treatment.

PURPOSE: Dynamic Spot-scanning Proton Arc (SPArc) therapy has gained attention for enhancing dosimetric plan quality. However, its full clinical imple...

Apr 20 2025 40474940
Intersecting impact of CAG repeat and huntingtin knockout in stem cell-derived cortical neurons.

Huntington's Disease (HD) is caused by a CAG repeat expansion in the gene encoding huntingtin (HTT). While normal HTT function appears impacted by the...

Apr 19 2025 40258535
Intelligent Care: A Scientometric Analysis of Artificial Intelligence in Precision Medicine.

The integration of advanced computational methods into precision medicine represents a transformative advancement in healthcare, enabling highly perso...

Apr 19 2025 40265391
Artificial intelligence (AI) in restorative dentistry: current trends and future prospects.

BACKGROUND: Artificial intelligence (AI) holds immense potential in revolutionizing restorative dentistry, offering transformative solutions for diagn...

Apr 18 2025 40251567
Fully Automated Online Adaptive Radiation Therapy Decision-Making for Cervical Cancer Using Artificial Intelligence.

BACKGROUND: Interfraction variations during radiation therapy pose a challenge for patients with cervical cancer, highlighting the benefits of online ...

Apr 17 2025 40252932
Multiscale metal-based nanocomposites for bone and joint disease therapies.

Bone and joint diseases are debilitating conditions that can result in significant functional impairment or even permanent disability. Multiscale meta...

Apr 17 2025 40290898
Optimal structural characteristics of osteoinductivity in bioceramics derived from a novel high-throughput screening plus machine learning approach.

Osteoinduction is an important feature of the next generation of bone repair materials. But the key structural factors and parameters of osteoinductiv...

Apr 16 2025 40262463
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