Stem Cell Research

Economic and utilization outcomes of medication management at a large Medicaid plan with disease management pharmacists using a novel artificial intelligence platform from 2018 to 2019: a retrospective observational study using regression methods.

Medication therapy management (MTM) and comprehensive medication management (CMM) have been practiced by clinical pharmacists as a predominantly manual activity with interventions documented in a record-keeping system. Program evaluations, largely based on estimations of projected savings and utilization reductions, have not accurately predicted actual claims and utilization changes, leading many...

Ischemic stroke-induced polyaxonal innervation at the neuromuscular junction is attenuated by robot-assisted mechanical therapy.

Ischemic stroke is a leading cause of disability world-wide. Mounting evidence supports neuromuscular pathology following stroke, yet mechanisms of dysfunction and therapeutic action remain undefined. The objectives of our study were to investigate neuromuscular pathophysiology following ischemic stroke and to evaluate the therapeutic effect of Robot-Assisted Mechanical massage Therapy (RAMT) on n...

Translational Applications of Artificial Intelligence and Machine Learning for Diagnostic Pathology in Lymphoid Neoplasms: A Comprehensive and Evolutive Analysis.

Genomic analysis and digitalization of medical records have led to a big data scenario within hematopathology. Artificial intelligence and machine lea...

Learning on knowledge graph dynamics provides an early warning of impactful research.

The scientific ecosystem relies on citation-based metrics that provide only imperfect, inconsistent and easily manipulated measures of research qualit...

Moving Forward in the Next Decade: Radiation Oncology Sciences for Patient-Centered Cancer Care.

In a time of rapid advances in science and technology, the opportunities for radiation oncology are undergoing transformational change. The linkage be...

Randomised controlled trials in medical AI: ethical considerations.

In recent years, there has been a surge of high-profile publications on applications of artificial intelligence (AI) systems for medical diagnosis and...

Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits.

Synaptic plasticity is believed to be a key physiological mechanism for learning. It is well established that it depends on pre- and postsynaptic acti...

An open-source semi-automated robotics pipeline for embryo immunohistochemistry.

A significant challenge for developmental systems biology is balancing throughput with controlled conditions that minimize experimental artifacts. Lar...

Artificial intelligence in oncology: Path to implementation.

In recent years, the field of artificial intelligence (AI) in oncology has grown exponentially. AI solutions have been developed to tackle a variety o...

A combined microfluidic deep learning approach for lung cancer cell high throughput screening toward automatic cancer screening applications.

Lung cancer is a leading cause of cancer death in both men and women worldwide. The high mortality rate in lung cancer is in part due to late-stage di...

Adjuvant Therapy System of COVID-19 Patient: Integrating Warning, Therapy, Post-Therapy Psychological Intervention.

The 2019 novel coronavirus(COVID-19) spreads rapidly, and the large-scale infection leads to the lack of medical resources. For the purpose of providi...

Ensuring that biomedical AI benefits diverse populations.

Artificial Intelligence (AI) can potentially impact many aspects of human health, from basic research discovery to individual health assessment. It is...

Machine learning-assisted immune profiling stratifies peri-implantitis patients with unique microbial colonization and clinical outcomes.

The endemic of peri-implantitis affects over 25% of dental implants. Current treatment depends on empirical patient and site-based stratifications an...

How Blue is the Sky?

The recent trend toward an industrialization of brain exploration and the technological prowess of artificial intelligence algorithms and high-perform...

Overcoming Immunological Challenges Limiting Capsid-Mediated Gene Therapy With Machine Learning.

A key hurdle to making adeno-associated virus (AAV) capsid mediated gene therapy broadly beneficial to all patients is overcoming pre-existing and the...

Machine learning-assisted high-content analysis of pluripotent stem cell-derived embryos in vitro.

Stem cell-based embryo models by cultured pluripotent and extra-embryonic lineage stem cells are novel platforms to model early postimplantation devel...

Are social robots ready yet to be used in care and therapy of autism spectrum disorder: A systematic review of randomized controlled trials.

Autism is a neurodevelopmental disorder that affects the everyday life of people who have this lifelong condition. Robots hold great promise for uplif...

Magnetic tri-bead microrobot assisted near-infrared triggered combined photothermal and chemotherapy of cancer cells.

Magnetic micro/nanorobots attracted much attention in biomedical fields because of their precise movement, manipulation, and targeting abilities. Howe...

Understanding the role of digital platforms in technology readiness.

State-of-the-art digital tools that take advantage of machine learning-derived algorithms and advanced data analytics have the potential to transform ...

Label-free quality control and identification of human keratinocyte stem cells by deep learning-based automated cell tracking.

Stem cell-based products have clinical and industrial applications. Thus, there is a need to develop quality control methods to standardize stem cell ...