Latest AI and machine learning research in steroids for healthcare professionals.
INTRODUCTION: Vancomycin is widely used for severe Gram‑positive infections in children, but vancomycin‑induced nephrotoxicity (VIN) limits its safe application. Existing prediction models rely primarily on traditional logistic regression with limited discriminative performance in pediatric populations, and machine learning (ML) approaches have not been systematically evaluated. AIM: This study ai...
PURPOSE: Delayed graft function (DGF) remains a significant complication following deceased donor kidney transplantation. This study aimed to develop and validate a multidimensional machine learning model for predicting DGF by integrating clinical data, machine perfusion parameters, donor scores, and histopathological scores. METHODS: A retrospective analysis was conducted on 961 deceased donor ki...
UNLABELLED: This study shows that an artificial intelligence tool can identify patterns of reduced bone mineral density in routine CT scans that would...
While apigenin shows therapeutic potential for bone-related disorders like osteoporosis and osteoarthritis, its mechanisms in regulating ligamentum fl...
Sarcopenia and osteoporosis are characterized by insufficient mass and function of skeletal muscle and bone, and often co-occur in older persons, a co...
BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by marked heterogeneity and an immunosuppressive microenvironment in which tumor-associate...
BACKGROUND: Ovarian cancer remains the deadliest gynecological malignancy, with neoadjuvant chemotherapy (NACT) often leaving residual fibroblast-enri...
With an almost 20-year experience with asthma biologics, it is now clear that a major impact of all available asthma biologics is the opportunity to r...
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening hematologic emergency that leads to increased complexities and mortality due to ...
Sex steroid hormones, including estradiol (E2), estrone (E1), follicle-stimulating hormone (FSH), and luteinizing hormone (LH), have been implicated i...
BACKGROUND: Adhesive capsulitis, commonly known as frozen shoulder, presents with pain and restricted movement. Treatments include physical therapy fo...
BACKGROUND: Sunitinib resistance remains a major clinical challenge in renal cell carcinoma, and the underlying molecular mechanisms are incompletely ...
BACKGROUND: Suspected invasive pulmonary aspergillosis (IPA) is increasingly treated in intensive care, including in patients without classical immuno...
OBJECTIVES: Osteoporosis and fragility fractures are clinically important complications of primary Sjögren's syndrome (pSS) that may accelerate functi...
Brain cancer is one of the most challenging malignancies and a major contributor to worldwide morbidity and mortality. Glioblastoma, the most aggressi...
OBJECTIVE: To evaluate the current evidence regarding airway and gut microbiome alterations in asthma pathogenesis and therapeutic response, and to ex...
INTRODUCTION: Intracranial aneurysms (IA) and osteoporosis (OP) are both common conditions among the elderly population. Observational studies suggest...
Synergizing radiotherapy (RT) with immune checkpoint inhibitors has emerged as a promising strategy for solid tumors. RT acts as a potent immunomodula...
Thymic epithelial tumors (TETs) are rare and heterogeneous malignancies whose aggressive epithelial states and microenvironmental organization remain ...
The adrenomedullin receptor signaling pathway plays a crucial role in tumor progression, yet its comprehensive implication in hepatocellular carcinoma...