Latest AI and machine learning research in steroids for healthcare professionals.
Effective treatment of diabetic osteoporotic fractures (DOF) requires biomaterials capable of promoting vascularized bone regeneration. A biodegradable porous zinc (Zn) scaffold incorporating sustained-release Notoginsenoside R1 (NGR1), referred to as Zn-NGR1, was developed using powder metallurgy and impregnation techniques. Comprehensive characterization by scanning electron microscopy (SEM), en...
OBJECTIVE: This study aimed to develop and evaluate a deep learning model based on the Vision Transformer (ViT) architecture for the automatic classification of hip X-ray images into three categories: normal bone mass, osteopenia, and osteoporosis. The goal was to explore the model's potential for early screening and auxiliary diagnosis of osteoporosis. METHODS: A total of 3016 hip anteroposterior...
BACKGROUND: Osteoporosis (OP) is projected to be a major issue significantly impacting the well-being of middle-aged and old populations. Machine lear...
Glucocorticoid (GC) therapy has been a cornerstone of critical care; however, its full potential has been constrained by fixed-dose regimens and trial...
INTRODUCTION: Artificial intelligence (AI) is becoming increasingly integrated into clinical care in hand surgery. Its applications extend across diag...
B-cell-directed immunotherapy holds great promise for treating solid tumors, where barriers such as desmoplastic stroma and low immunogenicity have li...
Non-small cell lung cancer (NSCLC) presents persistent challenges in immunotherapy, as the clinical benefit of programmed cell death protein 1 (PD-1) ...
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, remains a major global health concern due to its high incidence and mort...
The immunosuppressive tumor microenvironment (TME) enables cancer cells to evade clinical immunotherapies. Neural networks are vital components of the...
Chimeric antigen receptor T-cell (CAR-T) therapy has achieved unprecedented success in hematological malignancies but faces formidable challenges in s...
BACKGROUND: Lung adenocarcinoma (LUAD) remains a major clinical challenge in assessment of clinical outcomes and therapeutic response. Although tumor-...
BACKGROUND: Osteoporosis and sarcopenia are age-related degenerative diseases that frequently co-occur in the older adults, yet their shared molecular...
BackgroundSystemic lupus erythematosus (SLE), an autoimmune disease, predominantly affects women and is associated with an increased risk of spontaneo...
BACKGROUND: Aggression, which is highly prevalent in patients with mood disorders, has been proven valuable in detecting the progression from hypomani...
To investigate the role of lipid metabolism abnormalities in the progression of osteoporosis (OP), clarify the impact of the key regulator angiopoieti...
Early-onset colorectal cancer (EOCRC), diagnosed in patients under 50, is particularly aggressive, yet lacks targeted therapeutic strategies. This stu...
Acylation modification plays a crucial role in modulating head and neck squamous cell carcinoma (HNSCC) progression, and their specific prognostic imp...
Cervical cancer (CC) is still a major gynecological tumor among women globally. The heterogeneity landscape and prognostic value of metabolic reprogra...
BACKGROUND: Rat models are widely used in preclinical osteoporosis research to study disease mechanisms and evaluate therapies. Current Micro-CT studi...
OBJECTIVE: The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyr...